IL45585A - 6,11-dihydrodibenz(b,e)oxepin-acetic acids and derivative - Google Patents
6,11-dihydrodibenz(b,e)oxepin-acetic acids and derivativeInfo
- Publication number
- IL45585A IL45585A IL7445585A IL4558574A IL45585A IL 45585 A IL45585 A IL 45585A IL 7445585 A IL7445585 A IL 7445585A IL 4558574 A IL4558574 A IL 4558574A IL 45585 A IL45585 A IL 45585A
- Authority
- IL
- Israel
- Prior art keywords
- oxepin
- dihydro
- acetic acid
- oxodibenz
- ethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39480173A | 1973-09-06 | 1973-09-06 | |
US05/459,774 US4585788A (en) | 1973-09-06 | 1974-04-10 | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IL45585A0 IL45585A0 (en) | 1974-11-29 |
IL45585A true IL45585A (en) | 1977-06-30 |
Family
ID=27014870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL7445585A IL45585A (en) | 1973-09-06 | 1974-09-03 | 6,11-dihydrodibenz(b,e)oxepin-acetic acids and derivative |
Country Status (17)
Country | Link |
---|---|
US (1) | US4585788A (da) |
JP (1) | JPS5058084A (da) |
AT (1) | AT342053B (da) |
AU (1) | AU499709B2 (da) |
CA (1) | CA1153384A (da) |
CH (2) | CH609960A5 (da) |
DE (1) | DE2442060A1 (da) |
DK (1) | DK470574A (da) |
FI (1) | FI66368C (da) |
FR (1) | FR2242976B1 (da) |
GB (1) | GB1481866A (da) |
IE (1) | IE39835B1 (da) |
IL (1) | IL45585A (da) |
NL (1) | NL7411565A (da) |
NO (1) | NO142397C (da) |
SE (1) | SE7411156L (da) |
YU (2) | YU239574A (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56156273A (en) | 1980-03-31 | 1981-12-02 | Dainippon Pharmaceut Co Ltd | Acetic derivative |
DE3125374A1 (de) * | 1981-06-27 | 1983-01-13 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von heteroaryl- und dibenzoxepinalkansaeuren |
US4515946A (en) * | 1981-12-23 | 1985-05-07 | Hoechst-Roussel Pharmaceuticals Inc. | 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives |
US4576960A (en) * | 1981-12-23 | 1986-03-18 | Hoechst Roussel Pharmaceuticals Incorporated | 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives |
US4526891A (en) * | 1983-03-10 | 1985-07-02 | Hoechst Roussel Pharmaceuticals Inc. | Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins |
EP0188802A3 (en) * | 1984-12-26 | 1986-08-20 | Kyowa Hakko Kogyo Co., Ltd. | Dibenz (b,e) oxepin derivative and antiallergic agent |
FR2580280B1 (fr) * | 1985-04-11 | 1987-05-22 | Synthelabo | Derives d'acide dibenzo(be)oxepinne-acetique, leur preparation et leur application en therapeutique |
JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
FR2608606B1 (fr) * | 1986-12-22 | 1989-03-10 | Synthelabo | Derives d'acide dibenzo(be)oxepinne-acetique, leur preparation et leur application en therapeutique |
US4882351A (en) * | 1987-10-14 | 1989-11-21 | Roussel Uclaf | Tricyclic compounds |
AU612437B2 (en) * | 1987-12-14 | 1991-07-11 | Kyowa Hakko Kogyo Co. Ltd. | Tricyclic compounds |
CA1338625C (en) * | 1988-06-09 | 1996-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5242931A (en) * | 1988-06-09 | 1993-09-07 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds as TXA2 antagonists |
KR920003928B1 (ko) * | 1988-09-20 | 1992-05-18 | 히사미쯔세이야꾸 가부시기가이샤 | 신규의 디벤즈[b,e]옥세핀유도체 |
TW209861B (da) * | 1989-08-25 | 1993-07-21 | Hoechst Roussel Pharma | |
US5840749A (en) * | 1989-08-25 | 1998-11-24 | Hoechst Marion Roussel, Inc. | N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues |
US5574173A (en) * | 1993-12-06 | 1996-11-12 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
US6989462B2 (en) * | 2003-03-25 | 2006-01-24 | Sanofi-Aventis Deutschland Gmbh | Synthesis of 2-chloromethyl-6-methylbenzoic ester |
US7687646B2 (en) * | 2006-03-28 | 2010-03-30 | Azad Pharmaceutical Ingredients, Ag | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof |
WO2008023810A1 (fr) * | 2006-08-21 | 2008-02-28 | Sumitomo Chemical Company, Limited | Ester méthylique de l'acide 2-(4-méthoxycarbonylméthylphénoxyméthyl) benzoïque et son procédé de fabrication |
JP5139016B2 (ja) * | 2006-10-02 | 2013-02-06 | 住友化学株式会社 | オキソジベンゾオキセピン酢酸第3級アルキルエステルの製造方法 |
CN101516865B (zh) * | 2006-10-02 | 2013-01-23 | 住友化学株式会社 | 氧代二苯并氧杂*乙酸的叔烷基酯 |
EP2666770A1 (en) | 2008-07-16 | 2013-11-27 | Crystal Pharma S.A.U | Process for obtaining olopatadine and intermediates |
CN106518833A (zh) * | 2015-09-15 | 2017-03-22 | 江苏吉贝尔药业股份有限公司 | 一种新的6,11-二氢-11-氧代二苯并[b,e]噁庚因-2-乙酸制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS47425Y1 (da) * | 1968-03-14 | 1972-01-10 | ||
JPS48389Y1 (da) * | 1968-10-15 | 1973-01-08 | ||
US3702852A (en) * | 1970-02-24 | 1972-11-14 | Squibb & Sons Inc | Carboxylated dibenzoxazepines and dibenzothiazepines |
US3758528A (en) * | 1970-03-13 | 1973-09-11 | Science Union & Cie | Tricyclic compounds |
US3714201A (en) * | 1970-11-24 | 1973-01-30 | Squibb & Sons Inc | 5,11-dihydrodibenzoxa(or thia) zepine derivatives |
-
1974
- 1974-04-10 US US05/459,774 patent/US4585788A/en not_active Expired - Lifetime
- 1974-08-30 NL NL7411565A patent/NL7411565A/xx not_active Application Discontinuation
- 1974-09-03 CH CH675378A patent/CH609960A5/xx not_active IP Right Cessation
- 1974-09-03 IL IL7445585A patent/IL45585A/en unknown
- 1974-09-03 CH CH1195574A patent/CH615172A5/de not_active IP Right Cessation
- 1974-09-03 DE DE2442060A patent/DE2442060A1/de not_active Withdrawn
- 1974-09-04 SE SE7411156A patent/SE7411156L/xx unknown
- 1974-09-04 AU AU72962/74A patent/AU499709B2/en not_active Expired
- 1974-09-04 FI FI2583/74A patent/FI66368C/fi active
- 1974-09-05 NO NO74743203A patent/NO142397C/no unknown
- 1974-09-05 AT AT716474A patent/AT342053B/de not_active IP Right Cessation
- 1974-09-05 DK DK470574A patent/DK470574A/da not_active Application Discontinuation
- 1974-09-05 CA CA000208542A patent/CA1153384A/en not_active Expired
- 1974-09-05 IE IE1847/74A patent/IE39835B1/xx unknown
- 1974-09-06 FR FR7430329A patent/FR2242976B1/fr not_active Expired
- 1974-09-06 JP JP49102876A patent/JPS5058084A/ja active Pending
- 1974-09-06 GB GB39112/74A patent/GB1481866A/en not_active Expired
- 1974-09-15 YU YU02395/74A patent/YU239574A/xx unknown
-
1980
- 1980-09-12 YU YU02338/80A patent/YU233880A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
YU233880A (en) | 1983-04-27 |
FI66368B (fi) | 1984-06-29 |
US4585788A (en) | 1986-04-29 |
DE2442060A1 (de) | 1975-05-07 |
NO142397B (no) | 1980-05-05 |
YU239574A (en) | 1982-06-18 |
AT342053B (de) | 1978-03-10 |
FI258374A (da) | 1975-03-07 |
NO743203L (da) | 1975-04-01 |
JPS5058084A (da) | 1975-05-20 |
AU7296274A (en) | 1976-04-15 |
FR2242976B1 (da) | 1978-07-21 |
FI66368C (fi) | 1984-10-10 |
FR2242976A1 (da) | 1975-04-04 |
IE39835L (en) | 1975-03-06 |
GB1481866A (en) | 1977-08-03 |
IE39835B1 (en) | 1979-01-17 |
DK470574A (da) | 1975-05-05 |
CA1153384A (en) | 1983-09-06 |
CH609960A5 (da) | 1979-03-30 |
AU499709B2 (en) | 1979-05-03 |
SE7411156L (da) | 1975-03-07 |
CH615172A5 (da) | 1980-01-15 |
ATA716474A (de) | 1977-07-15 |
IL45585A0 (en) | 1974-11-29 |
NO142397C (no) | 1980-08-13 |
NL7411565A (nl) | 1975-03-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL45585A (en) | 6,11-dihydrodibenz(b,e)oxepin-acetic acids and derivative | |
EP0021228B1 (en) | 4-substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same | |
JPS6089482A (ja) | 抗ウイルス剤として有用な(置換)フエニル−脂肪族−イソオキサゾ−ルおよびその製法 | |
US4537902A (en) | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase | |
US4247706A (en) | Dibenzothiepin derivatives and a process for producing the same | |
KR0173455B1 (ko) | 치환된 피롤화합물 | |
FR2647676A1 (fr) | Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase | |
US4500731A (en) | Derivatives of 4-phenyl-4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and therapeutic uses for them | |
AU2003294861B2 (en) | Indenoncarboxylic acids derivatives and their use for the treatment of and preventing diabetes and dyslipidaemia | |
US4362891A (en) | Alkanoic acid derivatives | |
US4205087A (en) | Acetic acid derivatives | |
US4473583A (en) | Compositions containing certain derivatives of 4-phenyl-4-oxobuten-2-oic acid and methods of treatment using them | |
US4116972A (en) | Anti-inflammatory 1-oxo-isoindoline derivatives and processes for their preparation | |
US4356188A (en) | 1-Naphthyl-acetic acid derivatives and their therapeutic applications | |
JPS584699B2 (ja) | 置換フエニル酢酸誘導体及びその製法 | |
US3963758A (en) | 2-(Benzofuroyl)phenyl acetic acids | |
CH628014A5 (en) | Gamma-aryl-gamma-oxoisovaleric acids having antiphlogistic and antalgic properties | |
US4537906A (en) | Substituted phenylalkenoic acids and esters | |
US4690945A (en) | Process for the preparation of 5'-substituted 2-(3'-thienyl)propionic acids | |
US4816591A (en) | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | |
US4529737A (en) | Analgesic and anti-inflammatory arylalkanoic acid phthalidyl esters and pharmaceutical compositions thereof | |
IL32089A (en) | P-(pyrryl-1)-phenyl alkanoic acids,their preparation and pharmaceutical compositions containing them | |
US4778925A (en) | New benzoic acid derivatives, as well as processes for their production and their use as pharmaceuticals | |
EP0159684B1 (en) | (6,11-dihydro-11-oxodibenz(b,e)oxepinyl)pentanoic acids and derivatives, a process and intermediates for their preparation and their use as medicaments | |
KR790001825B1 (ko) | 스틸벤 유도체의 제조법 |