IL45422A - Alpha-(3,4,5-trisubstituted benzyl)-acrylonitriles and propionitriles and their preparation - Google Patents

Alpha-(3,4,5-trisubstituted benzyl)-acrylonitriles and propionitriles and their preparation

Info

Publication number
IL45422A
IL45422A IL45422A IL4542271A IL45422A IL 45422 A IL45422 A IL 45422A IL 45422 A IL45422 A IL 45422A IL 4542271 A IL4542271 A IL 4542271A IL 45422 A IL45422 A IL 45422A
Authority
IL
Israel
Prior art keywords
compounds
formula
propionitriles
acrylonitriles
alpha
Prior art date
Application number
IL45422A
Other languages
English (en)
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL45422A publication Critical patent/IL45422A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL45422A 1970-10-22 1971-10-21 Alpha-(3,4,5-trisubstituted benzyl)-acrylonitriles and propionitriles and their preparation IL45422A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (de) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (1)

Publication Number Publication Date
IL45422A true IL45422A (en) 1976-03-31

Family

ID=27255400

Family Applications (2)

Application Number Title Priority Date Filing Date
IL45422A IL45422A (en) 1970-10-22 1971-10-21 Alpha-(3,4,5-trisubstituted benzyl)-acrylonitriles and propionitriles and their preparation
IL37984A IL37984A (en) 1970-10-22 1971-10-21 2,4-diamino-5-benzylpyrimidine derivatives,their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL37984A IL37984A (en) 1970-10-22 1971-10-21 2,4-diamino-5-benzylpyrimidine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
JP (2) JPS5536662B1 (de)
AR (3) AR192588A1 (de)
AT (1) AT319948B (de)
BE (1) BE774281A (de)
BG (4) BG20797A3 (de)
CA (1) CA967158A (de)
CH (3) CH582681A5 (de)
DD (1) DD100877A5 (de)
DK (1) DK132174C (de)
ES (1) ES396219A1 (de)
FI (1) FI56175C (de)
FR (1) FR2111769B1 (de)
GB (1) GB1375162A (de)
IE (1) IE37452B1 (de)
IL (2) IL45422A (de)
LU (1) LU64129A1 (de)
MC (1) MC894A1 (de)
NL (1) NL175178C (de)
SE (2) SE384505B (de)
ZM (1) ZM14971A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
JPS54154775A (en) * 1978-05-24 1979-12-06 Wellcome Found Benzylpyrimidine derivative
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
CA2559036C (en) 2004-03-26 2013-08-20 Dainippon Sumitomo Pharma Co., Ltd. 9-substituted 8-oxoadenine compound
US8138172B2 (en) 2006-07-05 2012-03-20 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of TLR7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
JP5480637B2 (ja) 2007-03-19 2014-04-23 アストラゼネカ・アクチエボラーグ Toll様受容体(tlr7)モジュレーターとしての9−置換−8−オキソ−アデニン化合物
US8063051B2 (en) 2007-03-19 2011-11-22 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7) modulators
JPWO2008114819A1 (ja) 2007-03-20 2010-07-08 大日本住友製薬株式会社 新規アデニン化合物
PE20091236A1 (es) 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
PE20091156A1 (es) 2007-12-17 2009-09-03 Astrazeneca Ab Sales de (3-{[[3-(6-amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il)propil](3-morfolin-4-ilpropil)amino]metil}fenil)acetato de metilo
MX2011012337A (es) 2009-05-21 2011-12-08 Dainippon Sumitomo Pharma Co Nuevos derivados de pirimidina y su uso en el tratamiento de cancer y de otras enfermedades.
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
ES2575688T3 (es) 2010-12-16 2016-06-30 Sumitomo Dainippon Pharma Co., Ltd. Derivado de imidazo[4,5-c]quinolin-1-ilo útil en terapia
US8895570B2 (en) 2010-12-17 2014-11-25 Astrazeneca Ab Purine derivatives
AU2013261267B2 (en) 2012-05-18 2017-06-29 Sumitomo Pharma Co., Ltd. Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (de) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
ZM14971A1 (en) 1972-07-21
GB1375162A (de) 1974-11-27
DK132174C (da) 1976-03-29
ES396219A1 (es) 1975-09-16
AR192803A1 (es) 1973-03-14
NL7114494A (de) 1972-04-25
CA967158A (en) 1975-05-06
FR2111769A1 (de) 1972-06-09
MC894A1 (fr) 1972-06-22
AT319948B (de) 1975-01-10
DD100877A5 (de) 1973-10-12
IL37984A (en) 1976-03-31
NL175178C (nl) 1984-10-01
AR192588A1 (es) 1973-02-28
LU64129A1 (de) 1972-06-28
CH582681A5 (de) 1976-12-15
JPS53135991A (en) 1978-11-28
JPS5536662B1 (de) 1980-09-22
BG20797A3 (bg) 1975-12-20
IL37984A0 (en) 1971-12-29
BG21406A3 (bg) 1976-05-20
NL175178B (nl) 1984-05-01
BG20364A3 (bg) 1975-11-05
SE409705B (sv) 1979-09-03
IE37452L (en) 1972-04-22
IE37452B1 (en) 1977-08-03
AR192802A1 (es) 1973-03-14
BG20365A3 (bg) 1975-11-05
FI56175B (fi) 1979-08-31
CH568301A5 (de) 1975-10-31
CH568302A5 (de) 1975-10-31
DK132174B (da) 1975-11-03
FR2111769B1 (de) 1974-10-18
BE774281A (fr) 1972-04-21
SE384505B (sv) 1976-05-10
FI56175C (fi) 1979-12-10

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