JPS53135991A - Method of producing 2*44diaminoo55 benzylpyrimidine - Google Patents

Method of producing 2*44diaminoo55 benzylpyrimidine

Info

Publication number
JPS53135991A
JPS53135991A JP15499477A JP15499477A JPS53135991A JP S53135991 A JPS53135991 A JP S53135991A JP 15499477 A JP15499477 A JP 15499477A JP 15499477 A JP15499477 A JP 15499477A JP S53135991 A JPS53135991 A JP S53135991A
Authority
JP
Japan
Prior art keywords
benzylpyrimidine
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15499477A
Other languages
English (en)
Inventor
Rosu Baabara
Suchiyuaato Arekisandaa
Pataason Toomasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of JPS53135991A publication Critical patent/JPS53135991A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
JP15499477A 1970-10-22 1977-12-22 Method of producing 2*44diaminoo55 benzylpyrimidine Pending JPS53135991A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB963871*[A GB1375162A (ja) 1970-10-22 1970-10-22
GB963871 1971-04-16
GB4749171 1971-10-12

Publications (1)

Publication Number Publication Date
JPS53135991A true JPS53135991A (en) 1978-11-28

Family

ID=27255400

Family Applications (2)

Application Number Title Priority Date Filing Date
JP8365271A Pending JPS5536662B1 (ja) 1970-10-22 1971-10-21
JP15499477A Pending JPS53135991A (en) 1970-10-22 1977-12-22 Method of producing 2*44diaminoo55 benzylpyrimidine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP8365271A Pending JPS5536662B1 (ja) 1970-10-22 1971-10-21

Country Status (20)

Country Link
JP (2) JPS5536662B1 (ja)
AR (3) AR192588A1 (ja)
AT (1) AT319948B (ja)
BE (1) BE774281A (ja)
BG (4) BG20365A3 (ja)
CA (1) CA967158A (ja)
CH (3) CH582681A5 (ja)
DD (1) DD100877A5 (ja)
DK (1) DK132174C (ja)
ES (1) ES396219A1 (ja)
FI (1) FI56175C (ja)
FR (1) FR2111769B1 (ja)
GB (1) GB1375162A (ja)
IE (1) IE37452B1 (ja)
IL (2) IL45422A (ja)
LU (1) LU64129A1 (ja)
MC (1) MC894A1 (ja)
NL (1) NL175178C (ja)
SE (2) SE384505B (ja)
ZM (1) ZM14971A1 (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792096A (fr) * 1971-12-01 1973-05-30 Hoffmann La Roche Nouvelles benzylpyrimidines
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides
FI791638A (fi) * 1978-05-24 1979-11-25 Wellcome Found Bensylpyrimidinkompositioner
JPS61156909A (ja) * 1984-12-27 1986-07-16 Matsushita Electric Ind Co Ltd カレント・ミラ−回路
JPS62145907A (ja) * 1985-12-20 1987-06-30 Hitachi Ltd トランジスタ回路
NZ549903A (en) 2004-03-26 2010-04-30 Astrazeneca Ab 9-substituted 8-oxoadenine compound
WO2008004948A1 (en) 2006-07-05 2008-01-10 Astrazeneca Ab 8-oxoadenine derivatives acting as modulators of tlr7
TW200831105A (en) 2006-12-14 2008-08-01 Astrazeneca Ab Novel compounds
WO2008114006A1 (en) 2007-03-19 2008-09-25 Astrazeneca Ab 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7) modulators
EP2132209B8 (en) 2007-03-19 2014-04-16 AstraZeneca AB 9-substituted-8-oxo-adenine compounds as toll-like receptor (tlr7 ) modulators
US8044056B2 (en) 2007-03-20 2011-10-25 Dainippon Sumitomo Pharma Co., Ltd. Adenine compound
PE20091236A1 (es) * 2007-11-22 2009-09-16 Astrazeneca Ab Derivados de pirimidina como immunomoduladores de tlr7
UY31531A1 (es) 2007-12-17 2009-08-03 Sales derivadas de 8-oxoadenina composiciones farmacéuticas que las contienen y su uso en terapia como moduladores de receptor tipo toll (tlr)
EA201101650A1 (ru) 2009-05-21 2012-07-30 Астразенека Аб Новые производные пиримидина и их применение в лечении злокачественных новообразований и последующих заболеваний
GB0908772D0 (en) 2009-05-21 2009-07-01 Astrazeneca Ab New salts 756
JP5978225B2 (ja) 2010-12-16 2016-08-24 大日本住友製薬株式会社 治療に有用なイミダゾ[4,5−c]キノリン−1−イル誘導体
ES2627433T3 (es) 2010-12-17 2017-07-28 Sumitomo Dainippon Pharma Co., Ltd. Derivados de purina
SG11201407115XA (en) 2012-05-18 2014-12-30 Sumitomo Dainippon Pharma Co Ltd Carboxylic acid compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE710100A (ja) * 1967-02-02 1968-07-30
JPS511716A (ja) * 1974-06-25 1976-01-08 Toray Industries Horiesuterumaruchifuiramentono seiho

Also Published As

Publication number Publication date
NL7114494A (ja) 1972-04-25
AR192588A1 (es) 1973-02-28
JPS5536662B1 (ja) 1980-09-22
GB1375162A (ja) 1974-11-27
IL45422A (en) 1976-03-31
DD100877A5 (ja) 1973-10-12
BG21406A3 (ja) 1976-05-20
NL175178B (nl) 1984-05-01
LU64129A1 (ja) 1972-06-28
ZM14971A1 (en) 1972-07-21
FI56175C (fi) 1979-12-10
AR192803A1 (es) 1973-03-14
AR192802A1 (es) 1973-03-14
DK132174B (da) 1975-11-03
CH582681A5 (ja) 1976-12-15
IL37984A (en) 1976-03-31
BG20365A3 (ja) 1975-11-05
BG20364A3 (ja) 1975-11-05
IE37452L (en) 1972-04-22
CH568301A5 (ja) 1975-10-31
SE409705B (sv) 1979-09-03
CH568302A5 (ja) 1975-10-31
IL37984A0 (en) 1971-12-29
MC894A1 (fr) 1972-06-22
FR2111769B1 (ja) 1974-10-18
FI56175B (fi) 1979-08-31
IE37452B1 (en) 1977-08-03
CA967158A (en) 1975-05-06
BE774281A (fr) 1972-04-21
BG20797A3 (ja) 1975-12-20
FR2111769A1 (ja) 1972-06-09
ES396219A1 (es) 1975-09-16
NL175178C (nl) 1984-10-01
DK132174C (da) 1976-03-29
AT319948B (de) 1975-01-10
SE384505B (sv) 1976-05-10

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