IL42430A0 - Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them - Google Patents

Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL42430A0
IL42430A0 IL42430A IL4243073A IL42430A0 IL 42430 A0 IL42430 A0 IL 42430A0 IL 42430 A IL42430 A IL 42430A IL 4243073 A IL4243073 A IL 4243073A IL 42430 A0 IL42430 A0 IL 42430A0
Authority
IL
Israel
Prior art keywords
pyridopyrrolobenzheterocycles
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
IL42430A
Other languages
English (en)
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of IL42430A0 publication Critical patent/IL42430A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL42430A 1972-06-19 1973-06-04 Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them IL42430A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376672A 1972-06-09 1972-06-09
US357528A US3914421A (en) 1972-06-19 1973-05-07 Pyridopyrrolobenzheterocycles for combatting depression

Publications (1)

Publication Number Publication Date
IL42430A0 true IL42430A0 (en) 1973-08-29

Family

ID=26950035

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42430A IL42430A0 (en) 1972-06-19 1973-06-04 Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them

Country Status (7)

Country Link
US (1) US3914421A (pl)
BE (1) BE801108A (pl)
DE (1) DE2330719A1 (pl)
FR (1) FR2189048B1 (pl)
IL (1) IL42430A0 (pl)
LU (1) LU67815A1 (pl)
NL (1) NL7308525A (pl)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013652A (en) * 1972-06-19 1977-03-22 Endo Laboratories, Inc. Pyridopyrrolobenzoxazine
US4183936A (en) * 1972-06-19 1980-01-15 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4115577A (en) * 1972-06-19 1978-09-19 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
DE2922756A1 (de) * 1978-06-05 1979-12-06 Sankyo Co Benzothiazocine, benzothiazocinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung
US4219550A (en) * 1978-11-09 1980-08-26 E. I. Du Pont De Nemours And Company Cis- and trans- octahydropyridopyrrolobenzheterocycles
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0380155A1 (en) * 1989-01-19 1990-08-01 Duphar International Research B.V 8,9-Annelated-1,2,3,4-tetrahydro-beta-carboline derivatives
US7071186B2 (en) 1999-06-15 2006-07-04 Bristol-Myers Squibb Pharma Co. Substituted heterocycle fused gamma-carbolines
US6713471B1 (en) 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
EP1189904B1 (en) 1999-06-15 2004-09-22 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
DE60139511D1 (de) 2000-12-20 2009-09-17 Bristol Myers Squibb Co Substituierte pyrrolochinoline und pyridochinoline als serotonin- agonisten und- antagonisten
WO2002059129A2 (en) * 2000-12-20 2002-08-01 Bristol-Myers Squibb Company Substituted tetracyclic pyridoindoles as serotonin agonists and antagonists
US6849619B2 (en) * 2000-12-20 2005-02-01 Bristol-Myers Squibb Company Substituted pyridoindoles as serotonin agonists and antagonists
JP4346307B2 (ja) 2000-12-20 2009-10-21 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー セロトニン受容体アゴニストおよびアンタゴニストとしての置換されたピラジノキノキサリン誘導体
EP1429776A2 (en) 2001-09-21 2004-06-23 PHARMACIA & UPJOHN COMPANY Tricyclic indole derivatives as 5-ht ligands
WO2004056324A2 (en) * 2002-12-19 2004-07-08 Bristol-Myers Squibb Company Substituted tricyclic gamma-carbolines as serotonin receptor agonists and antagonists
MX2009009773A (es) 2007-03-12 2009-12-16 Intra Cellular Therapies Inc Sintesis de gamma-carbolinas fusionadas con heterociclo substituido.
US8575186B2 (en) 2009-10-05 2013-11-05 Albany Molecular Research, Inc. Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
WO2012099952A2 (en) 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
ES2727815T3 (es) 2012-04-14 2019-10-18 Intra Cellular Therapies Inc Tratamiento del TEPT y de trastornos del control de impulsos
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
KR102372145B1 (ko) 2013-12-03 2022-03-07 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
AU2015240526A1 (en) 2014-04-04 2016-11-24 Intra-Cellular Therapies, Inc. Organic compounds
ES2961843T3 (es) 2014-04-04 2024-03-14 Intra Cellular Therapies Inc Gamma-carbolinas condensadas con heterociclo deuteradas como antagonistas de los receptores de 5-HT2A
DK3407888T3 (da) 2016-01-26 2021-04-06 Intra Cellular Therapies Inc Pyridopyrroloquinoxalinforbindelser, deres sammensætninger og anvendelser
MX2018011676A (es) 2016-03-25 2018-12-19 Intra Cellular Therapies Inc Compuestos organicos.
JP2019513143A (ja) 2016-03-28 2019-05-23 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規塩類および結晶
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
EP3436016B1 (en) 2016-03-28 2022-04-27 Intra-Cellular Therapies, Inc. Novel co-crystals
WO2018071233A1 (en) 2016-10-12 2018-04-19 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
US10906906B2 (en) 2016-12-29 2021-02-02 Intra-Cellular Therapies, Inc. Organic compounds
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
KR102398194B1 (ko) 2017-03-24 2022-05-18 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 조성물 및 방법
IL272252B2 (en) 2017-07-26 2024-03-01 Intra Cellular Therapies Inc Transformed histories of gamma-carbolines fused with heterocyclics, pharmaceutical preparations containing them and their use for treatment
WO2019023062A1 (en) 2017-07-26 2019-01-31 Intra-Cellular Therapies, Inc. ORGANIC COMPOUNDS
MX2020013335A (es) 2018-06-08 2021-05-27 Intra Cellular Therapies Inc Metodos novedosos.
WO2019241278A1 (en) 2018-06-11 2019-12-19 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
US10695345B2 (en) 2018-08-31 2020-06-30 Intra-Cellular Therapies, Inc. Pharmaceutical capsule compositions comprising lumateperone mono-tosylate
CN112584837A (zh) 2018-08-31 2021-03-30 细胞内治疗公司 新方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH307223A (de) * 1952-04-28 1955-05-15 Bayer Ag Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins.

Also Published As

Publication number Publication date
BE801108A (fr) 1973-10-15
FR2189048A1 (pl) 1974-01-25
DE2330719A1 (de) 1974-01-10
NL7308525A (pl) 1973-12-21
FR2189048B1 (pl) 1976-10-22
US3914421A (en) 1975-10-21
LU67815A1 (pl) 1973-09-26

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