BE801108A - Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant - Google Patents

Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
BE801108A
BE801108A BE132425A BE132425A BE801108A BE 801108 A BE801108 A BE 801108A BE 132425 A BE132425 A BE 132425A BE 132425 A BE132425 A BE 132425A BE 801108 A BE801108 A BE 801108A
Authority
BE
Belgium
Prior art keywords
pyridopyrrolobenzheterocyclic
compounds
preparation
new
pharmaceutical compositions
Prior art date
Application number
BE132425A
Other languages
English (en)
Inventor
P Rajagopalan
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of BE801108A publication Critical patent/BE801108A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE132425A 1972-06-19 1973-06-19 Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant BE801108A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376672A 1972-06-09 1972-06-09
US357528A US3914421A (en) 1972-06-19 1973-05-07 Pyridopyrrolobenzheterocycles for combatting depression

Publications (1)

Publication Number Publication Date
BE801108A true BE801108A (fr) 1973-10-15

Family

ID=26950035

Family Applications (1)

Application Number Title Priority Date Filing Date
BE132425A BE801108A (fr) 1972-06-19 1973-06-19 Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant

Country Status (7)

Country Link
US (1) US3914421A (fr)
BE (1) BE801108A (fr)
DE (1) DE2330719A1 (fr)
FR (1) FR2189048B1 (fr)
IL (1) IL42430A0 (fr)
LU (1) LU67815A1 (fr)
NL (1) NL7308525A (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115577A (en) * 1972-06-19 1978-09-19 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4013652A (en) * 1972-06-19 1977-03-22 Endo Laboratories, Inc. Pyridopyrrolobenzoxazine
US4183936A (en) * 1972-06-19 1980-01-15 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
FR2428035A1 (fr) * 1978-06-05 1980-01-04 Sankyo Co Derives de benzothiazocine et de benzothiazonine, et leur application therapeutique
US4219550A (en) * 1978-11-09 1980-08-26 E. I. Du Pont De Nemours And Company Cis- and trans- octahydropyridopyrrolobenzheterocycles
EP0357417A1 (fr) * 1988-09-01 1990-03-07 Glaxo Group Limited Dérivés de lactames
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0380155A1 (fr) * 1989-01-19 1990-08-01 Duphar International Research B.V Dérivés de 1,2,3,4-tétrahydro-bêta-carboline, 8,9-annelés
NZ516031A (en) 1999-06-15 2003-10-31 Bristol Myers Squibb Pharma Co Substituted heterocycle fused gamma-carbolines
US6713471B1 (en) 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
US7071186B2 (en) 1999-06-15 2006-07-04 Bristol-Myers Squibb Pharma Co. Substituted heterocycle fused gamma-carbolines
US6849619B2 (en) * 2000-12-20 2005-02-01 Bristol-Myers Squibb Company Substituted pyridoindoles as serotonin agonists and antagonists
PL366627A1 (en) 2000-12-20 2005-02-07 Bristol-Myers Squibb Company Substituted pyrroloquinolines and pyridoquinolines as serotonin agonists and antagonists
EE200300296A (et) * 2000-12-20 2003-12-15 Bristol-Myers Squibb Company Asendatud püridoindoolid kui serotoniini agonistid ja antagonistid ning nende kasutamine
CA2431970A1 (fr) 2000-12-20 2002-08-01 Bristol-Myers Squibb Pharma Company Derives de pyrazinoquinoxaline substituee en tant qu'agonistes et antagonistes des recepteurs de serotonine
AU2002336749A1 (en) * 2001-09-21 2003-04-01 Pharmacia And Upjohn Company Tricyclic indole derivatives as 5-ht ligands
WO2004056324A2 (fr) * 2002-12-19 2004-07-08 Bristol-Myers Squibb Company Gamma-carbolines tricycliques substituees utilisees comme agonistes et antagonistes du recepteur de la serotonine
KR101999300B1 (ko) 2007-03-12 2019-07-12 인트라-셀룰라 써래피스, 인코퍼레이티드. 치환된 헤테로환 융합 감마-카르볼린 합성
WO2011044134A1 (fr) 2009-10-05 2011-04-14 Albany Molecular Research, Inc. Dérivés d'épiminocycloalkyl(b)indole utilisés en tant que modulateurs du récepteur de la sérotonine de sous-type 6 (5-ht6) et leurs utilisations
WO2012099952A2 (fr) 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c]pyridines et analogues associés en tant que modulateurs du sous-type 6 de la sérotonine (5-ht6) pour traitement de l'obésité, du syndrome métabolique, de la cognition et de la schizophrénie
US9428506B2 (en) 2012-04-14 2016-08-30 Intra-Cellular Therapies, Inc. Substituted pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalines for the treatment of nervous system disorders
EP2968320B1 (fr) 2013-03-15 2020-11-11 Intra-Cellular Therapies, Inc. Composés organiques
IL305990A (en) 2013-12-03 2023-11-01 Intra Cellular Therapies Inc Compressed gamma-carboline heterocyclic compounds are modified for use in the treatment of type I and/or type II bipolar disorders
WO2015154030A1 (fr) 2014-04-04 2015-10-08 Intra-Cellular Therapies, Inc. Composés organiques
ES2961843T3 (es) 2014-04-04 2024-03-14 Intra Cellular Therapies Inc Gamma-carbolinas condensadas con heterociclo deuteradas como antagonistas de los receptores de 5-HT2A
CN108883111B (zh) 2016-01-26 2021-10-08 细胞内治疗公司 有机化合物
AU2017238842B2 (en) 2016-03-25 2019-06-20 Intra-Cellular Therapies, Inc. Organic compounds
JP2019513143A (ja) 2016-03-28 2019-05-23 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規塩類および結晶
US10682354B2 (en) 2016-03-28 2020-06-16 Intra-Cellular Therapies, Inc. Compositions and methods
EP3436016B1 (fr) 2016-03-28 2022-04-27 Intra-Cellular Therapies, Inc. Nouveaux co-cristaux
WO2018071233A1 (fr) 2016-10-12 2018-04-19 Intra-Cellular Therapies, Inc. Dispersions solides amorphes
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
WO2018126143A1 (fr) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Composés organiques
IL268970B2 (en) 2017-03-24 2023-12-01 Intra Cellular Therapies Inc Oral preparations of heterocyclic gamma carboline derivatives fused for absorption through mucous membranes
WO2019023063A1 (fr) 2017-07-26 2019-01-31 Intra-Cellular Therapies, Inc. Composés organiques
JP7223742B2 (ja) 2017-07-26 2023-02-16 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
WO2019237037A1 (fr) 2018-06-08 2019-12-12 Intra-Cellular Therapies, Inc. Nouvelles méthodes
EP3609891A4 (fr) 2018-06-11 2021-04-14 Intra-Cellular Therapies, Inc. Synthèse de gamma-carbolines fusionnées à hétérocycles substitués
KR20210052472A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
CN112584837A (zh) 2018-08-31 2021-03-30 细胞内治疗公司 新方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH307223A (de) * 1952-04-28 1955-05-15 Bayer Ag Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins.

Also Published As

Publication number Publication date
DE2330719A1 (de) 1974-01-10
LU67815A1 (fr) 1973-09-26
NL7308525A (fr) 1973-12-21
US3914421A (en) 1975-10-21
FR2189048A1 (fr) 1974-01-25
IL42430A0 (en) 1973-08-29
FR2189048B1 (fr) 1976-10-22

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