BE801108A - Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant - Google Patents

Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
BE801108A
BE801108A BE132425A BE132425A BE801108A BE 801108 A BE801108 A BE 801108A BE 132425 A BE132425 A BE 132425A BE 132425 A BE132425 A BE 132425A BE 801108 A BE801108 A BE 801108A
Authority
BE
Belgium
Prior art keywords
pyridopyrrolobenzheterocyclic
compounds
preparation
new
pharmaceutical compositions
Prior art date
Application number
BE132425A
Other languages
English (en)
French (fr)
Inventor
P Rajagopalan
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of BE801108A publication Critical patent/BE801108A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE132425A 1972-06-19 1973-06-19 Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant BE801108A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376672A 1972-06-19 1972-06-19
US357528A US3914421A (en) 1972-06-19 1973-05-07 Pyridopyrrolobenzheterocycles for combatting depression

Publications (1)

Publication Number Publication Date
BE801108A true BE801108A (fr) 1973-10-15

Family

ID=26950035

Family Applications (1)

Application Number Title Priority Date Filing Date
BE132425A BE801108A (fr) 1972-06-19 1973-06-19 Nouveaux composes pyridopyrrolobenzheterocycliques leur preparation et compositions pharmaceutiques les contenant

Country Status (7)

Country Link
US (1) US3914421A (pl)
BE (1) BE801108A (pl)
DE (1) DE2330719A1 (pl)
FR (1) FR2189048B1 (pl)
IL (1) IL42430A0 (pl)
LU (1) LU67815A1 (pl)
NL (1) NL7308525A (pl)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013652A (en) * 1972-06-19 1977-03-22 Endo Laboratories, Inc. Pyridopyrrolobenzoxazine
US4115577A (en) * 1972-06-19 1978-09-19 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4183936A (en) * 1972-06-19 1980-01-15 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
GB2022093B (en) * 1978-06-05 1982-09-15 Sankyo Co Benzothalzocines and benzothiazonines
US4219550A (en) * 1978-11-09 1980-08-26 E. I. Du Pont De Nemours And Company Cis- and trans- octahydropyridopyrrolobenzheterocycles
EP0357417A1 (en) * 1988-09-01 1990-03-07 Glaxo Group Limited Lactam derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0380155A1 (en) * 1989-01-19 1990-08-01 Duphar International Research B.V 8,9-Annelated-1,2,3,4-tetrahydro-beta-carboline derivatives
US6713471B1 (en) 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
US7071186B2 (en) 1999-06-15 2006-07-04 Bristol-Myers Squibb Pharma Co. Substituted heterocycle fused gamma-carbolines
BR0012086A (pt) 1999-06-15 2002-04-02 Bristol Myers Squibb Pharma Co Compostos derivados de gama-carbolinas fundidas com heterociclos substituìdos, composição farmacêutica e usos dos compostos
PL366233A1 (pl) * 2000-12-20 2005-01-24 Bristol-Myers Squibb Company Podstawione pirydoindole jako agoniści i antagoniści serotoniny
US6849619B2 (en) * 2000-12-20 2005-02-01 Bristol-Myers Squibb Company Substituted pyridoindoles as serotonin agonists and antagonists
RU2003121406A (ru) 2000-12-20 2004-12-27 Бристол-Маерс Сквибб Фарма Компани (Us) Производные замещенных пиразинохиноксалинов в качестве агонистов и антагонистов рецептора серотонина
PL366627A1 (pl) 2000-12-20 2005-02-07 Bristol-Myers Squibb Company Podstawione pirolochinoliny i pirydochinoliny jako agoniści i antagoniści serotoniny
CA2460126A1 (en) 2001-09-21 2003-03-27 Pharmacia & Upjohn Company Tricyclic indole derivatives as 5-ht ligands
EP1581221B1 (en) * 2002-12-19 2011-05-18 Bristol-Myers Squibb Company Substituted tricyclic gamma-carbolines as serotonin receptor agonists and antagonists
KR102065319B1 (ko) * 2007-03-12 2020-01-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 치환된 헤테로환 융합 감마-카르볼린 합성
WO2011044134A1 (en) 2009-10-05 2011-04-14 Albany Molecular Research, Inc. Epiminocycloalkyl(b)indole derivatives as serotonin sub-type 6 (5-ht6) modulators and uses thereof
CA2823955A1 (en) 2011-01-19 2012-07-26 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-ht6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
KR20140146192A (ko) 2012-04-14 2014-12-24 인트라-셀룰라 써래피스, 인코퍼레이티드. 유기 화합물
HUE053159T2 (hu) 2013-03-15 2021-06-28 Intra Cellular Therapies Inc Szerves vegyületek
CN114366741A (zh) 2013-12-03 2022-04-19 细胞内治疗公司 新方法
US10077267B2 (en) 2014-04-04 2018-09-18 Intra-Cellular Therapies, Inc. Organic compounds
US9745300B2 (en) 2014-04-04 2017-08-29 Intra-Cellular Therapies, Inc. Organic compounds
IL260653B2 (en) 2016-01-26 2023-03-01 Intra Cellular Therapies Inc Condensed gamma carbonyls are heterocyclically converted
ES2879888T3 (es) 2016-03-25 2021-11-23 Intra Cellular Therapies Inc Compuestos orgánicos y su uso en el tratamiento o prevención de trastornos del sistema nervioso central
JP6997718B2 (ja) 2016-03-28 2022-01-18 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規共結晶
WO2017172784A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel salts and crystals
WO2017172795A1 (en) 2016-03-28 2017-10-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
JP7013454B2 (ja) 2016-10-12 2022-02-15 イントラ－セルラー・セラピーズ・インコーポレイテッド アモルファス固体分散体
WO2018126140A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
US10906906B2 (en) 2016-12-29 2021-02-02 Intra-Cellular Therapies, Inc. Organic compounds
BR112019019875A2 (pt) 2017-03-24 2020-04-22 Intra Cellular Therapies Inc novas composições e métodos
IL272252B2 (en) 2017-07-26 2024-03-01 Intra Cellular Therapies Inc Transformed histories of gamma-carbolines fused with heterocyclics, pharmaceutical preparations containing them and their use for treatment
BR112020001666A2 (pt) 2017-07-26 2020-07-21 Intra-Cellular Therapies, Inc. compostos orgânicos
WO2019241278A1 (en) 2018-06-11 2019-12-19 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
BR112021003655A2 (pt) 2018-08-31 2021-05-18 Intra-Cellular Therapies, Inc. métodos novos
US10695345B2 (en) 2018-08-31 2020-06-30 Intra-Cellular Therapies, Inc. Pharmaceutical capsule compositions comprising lumateperone mono-tosylate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH307223A (de) * 1952-04-28 1955-05-15 Bayer Ag Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins.

Also Published As

Publication number Publication date
FR2189048A1 (pl) 1974-01-25
US3914421A (en) 1975-10-21
FR2189048B1 (pl) 1976-10-22
IL42430A0 (en) 1973-08-29
NL7308525A (pl) 1973-12-21
LU67815A1 (pl) 1973-09-26
DE2330719A1 (de) 1974-01-10

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