IL42430A0 - Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them - Google Patents

Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL42430A0
IL42430A0 IL42430A IL4243073A IL42430A0 IL 42430 A0 IL42430 A0 IL 42430A0 IL 42430 A IL42430 A IL 42430A IL 4243073 A IL4243073 A IL 4243073A IL 42430 A0 IL42430 A0 IL 42430A0
Authority
IL
Israel
Prior art keywords
pyridopyrrolobenzheterocycles
preparation
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
IL42430A
Other languages
English (en)
Original Assignee
Endo Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endo Lab filed Critical Endo Lab
Publication of IL42430A0 publication Critical patent/IL42430A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/18—Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL42430A 1972-06-19 1973-06-04 Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them IL42430A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26376672A 1972-06-19 1972-06-19
US357528A US3914421A (en) 1972-06-19 1973-05-07 Pyridopyrrolobenzheterocycles for combatting depression

Publications (1)

Publication Number Publication Date
IL42430A0 true IL42430A0 (en) 1973-08-29

Family

ID=26950035

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42430A IL42430A0 (en) 1972-06-19 1973-06-04 Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them

Country Status (7)

Country Link
US (1) US3914421A (en:Method)
BE (1) BE801108A (en:Method)
DE (1) DE2330719A1 (en:Method)
FR (1) FR2189048B1 (en:Method)
IL (1) IL42430A0 (en:Method)
LU (1) LU67815A1 (en:Method)
NL (1) NL7308525A (en:Method)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4183936A (en) * 1972-06-19 1980-01-15 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4115577A (en) * 1972-06-19 1978-09-19 Endo Laboratories, Inc. Pyridopyrrolobenzheterocycles
US4013652A (en) * 1972-06-19 1977-03-22 Endo Laboratories, Inc. Pyridopyrrolobenzoxazine
CH644602A5 (de) * 1978-06-05 1984-08-15 Sankyo Co Benzothiazocin- und benzothiazoninderivate, ihre herstellung und diese derivate enthaltende pharmazeutische praeparate.
US4219550A (en) * 1978-11-09 1980-08-26 E. I. Du Pont De Nemours And Company Cis- and trans- octahydropyridopyrrolobenzheterocycles
US4997831A (en) * 1988-09-01 1991-03-05 Glaxo Group Limited Lactam derivatives
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
EP0380155A1 (en) * 1989-01-19 1990-08-01 Duphar International Research B.V 8,9-Annelated-1,2,3,4-tetrahydro-beta-carboline derivatives
US7071186B2 (en) 1999-06-15 2006-07-04 Bristol-Myers Squibb Pharma Co. Substituted heterocycle fused gamma-carbolines
US6713471B1 (en) 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
WO2000077010A2 (en) 1999-06-15 2000-12-21 Du Pont Pharmaceuticals Company Substituted heterocycle fused gamma-carbolines
HUP0303432A3 (en) * 2000-12-20 2012-09-28 Bristol Myers Squibb Co Substituted pyridoindoles as serotonin agonists and antagonists and pharmaceutical compositions containing the compounds and their use
US6849619B2 (en) * 2000-12-20 2005-02-01 Bristol-Myers Squibb Company Substituted pyridoindoles as serotonin agonists and antagonists
RU2003121306A (ru) 2000-12-20 2005-03-10 Бристол-Маерс Сквибб Компани (Us) Бристол-Маерс Сквибб Компани (Us) Замещенные пирролохинолины и пиридохинолины в качестве агонистов и антагонистов серотонина
CA2431970A1 (en) 2000-12-20 2002-08-01 Bristol-Myers Squibb Pharma Company Substituted pyrazinoquinoxaline derivatives as serotonin receptor agonists and antagonists
MXPA04002615A (es) 2001-09-21 2004-07-08 Upjohn Co Compuestos del ligando 5-ht terapeuticos.
ES2364046T3 (es) * 2002-12-19 2011-08-23 Bristol-Myers Squibb Company Gamma-carbolinas tricíclicas sustituidas utilizadas como agonistas y antagonistas de los receptores de la serotonina.
AU2008226814C1 (en) 2007-03-12 2014-11-20 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
US8575186B2 (en) 2009-10-05 2013-11-05 Albany Molecular Research, Inc. Epiminocycloalkyl[b] indole derivatives as serotonin sub-type 6 (5-HT6) modulators and uses thereof
US9067949B2 (en) 2011-01-19 2015-06-30 Albany Molecular Research, Inc. Benzofuro[3,2-c] pyridines and related analogs as serotonin sub-type 6 (5-HT6) modulators for the treatment of obesity, metabolic syndrome, cognition and schizophrenia
JP6334511B2 (ja) 2012-04-14 2018-05-30 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規方法
PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
JP6475727B2 (ja) 2013-12-03 2019-02-27 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 新規方法
US9745300B2 (en) 2014-04-04 2017-08-29 Intra-Cellular Therapies, Inc. Organic compounds
MX2021014508A (es) 2014-04-04 2023-05-18 Intra Cellular Therapies Inc Gamma-carbolinas fusionadas con heterociclos sustituidas con deuterio.
PL3838274T3 (pl) 2016-01-26 2024-04-02 Intra-Cellular Therapies, Inc. Pochodna pirydo[3',4':4,5]pirolo[1,2,3-DE]chinoksaliny do zastosowania w leczeniu zaburzeń OUN
IL281050B2 (en) 2016-03-25 2023-04-01 Intra Cellular Therapies Inc A controlled or delayed release pharmaceutical preparation containing a deuterated compound
US11014925B2 (en) 2016-03-28 2021-05-25 Intra-Cellular Therapies, Inc. Co-crystals of 1-(4-fluoro-phenyl)-4-((6bR,1OaS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H,7H- pyrido[3′,4′:4,51_pyrrolo [1,2,3-delqcuinoxalin-8-yl)-butan-1-one with nicotinamide or isonicotinamide
EP3436083A4 (en) 2016-03-28 2019-11-27 Intra-Cellular Therapies, Inc. NOVEL COMPOSITIONS AND METHOD
US10654854B2 (en) 2016-03-28 2020-05-19 Intra-Cellular Therapies, Inc. Salts and crystals of ITI-007
CN110072518B (zh) 2016-10-12 2021-10-26 细胞内治疗公司 无定形固体分散体
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
WO2018126143A1 (en) 2016-12-29 2018-07-05 Intra-Cellular Therapies, Inc. Organic compounds
CN116327770A (zh) 2017-03-24 2023-06-27 细胞内治疗公司 新组合物和方法
US11427587B2 (en) 2017-07-26 2022-08-30 Intra-Cellular Therapies, Inc. Organic compounds
CN111093665A (zh) 2017-07-26 2020-05-01 细胞内治疗公司 有机化合物
BR112020019119A2 (pt) 2018-03-23 2021-01-12 Intra-Cellular Therapies, Inc. Compostos orgânicos
EP3628007B1 (en) 2018-06-06 2023-05-03 Intra-Cellular Therapies, Inc. Novel salts and crystals
ES3028377T3 (en) 2018-06-08 2025-06-19 Intra Cellular Therapies Inc Fused gamma-carbolines for acute treatment of anxiety or depression
WO2019241278A1 (en) 2018-06-11 2019-12-19 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines synthesis
WO2020047241A1 (en) 2018-08-29 2020-03-05 Intra-Cellular Therapies, Inc. Novel compositions and methods
KR20210052471A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
BR112021003838A2 (pt) 2018-08-31 2021-05-18 Intra-Cellular Therapies, Inc. métodos novos
KR20220029744A (ko) 2019-07-07 2022-03-08 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH307223A (de) * 1952-04-28 1955-05-15 Bayer Ag Verfahren zur Herstellung eines Derivates des Tetrahydro-y-carbolins.

Also Published As

Publication number Publication date
FR2189048B1 (en:Method) 1976-10-22
DE2330719A1 (de) 1974-01-10
NL7308525A (en:Method) 1973-12-21
US3914421A (en) 1975-10-21
BE801108A (fr) 1973-10-15
FR2189048A1 (en:Method) 1974-01-25
LU67815A1 (en:Method) 1973-09-26

Similar Documents

Publication Publication Date Title
IL42430A0 (en) Pyridopyrrolobenzheterocycles,their preparation and pharmaceutical compositions containing them
IL43762A (en) 11,11-alkylidene-steroids their preparation and pharmaceutical compositions containing them
IL42158A0 (en) Novel benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL43837A0 (en) New aminophenyl-ethanolamines and corresponding oxazolidines,their preparation and pharmaceutical compositions containing them
IL40184A0 (en) 5-cinnamoyl-benzofurans,their preparation and pharmaceutical compositions containing them
IL43001A0 (en) Novel 4-biphenylyl-alcohols,their preparation and pharmaceutical compositions containing them
IL42429A0 (en) 2-alkoxycephalosporins,their preparation and pharmaceutical compositions containing them
IL49286A0 (en) Novel 1-iodo-1-trans-alkenes,their preparation and pharmaceutical compositions containing them
IL43913A0 (en) Novel cephalosporins,their preparation and pharmaceutical compositions containing them
IL43283A0 (en) Indoloquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL41512A0 (en) New oxazoles,their preparation and pharmaceutical compositions containing them
IL43002A0 (en) Novel biphenylyl derivatives,their preparation and pharmaceutical compositions containing them
IL42790A0 (en) 4a-aryl-trans-decahydroisoquino-lines,their preparation and pharmaceutical compositions containing them
IL40747A0 (en) 1-phenyl-3-hydroxy-3-methyl-triazenes,their preparation and pharmaceutical compositions containing them
IL42613A0 (en) Amino-imidazo-and amino-pyrazolo-isoquinolines,their preparation and pharmaceutical compositions containing them
IL41463A0 (en) Novel benzylpyrimidines,their manufacture and pharmaceutical compositions containing them
IL36743A (en) Phenylaminoalkanes,their preparation and pharmaceutical compositions containing them
IL43736A0 (en) Novel biphenyl derivatives,their preparation and pharmaceutical compositions containing them
IL37588A0 (en) Pyrimidoisoquinolines,their preparation and pharmaceutical compositions containing them
IL41715A0 (en) Diphenylmethane derivatives,their preparation and pharmaceutical compositions containing them
IL42354A0 (en) Anhydrofuranose derivatives,their manufacture and pharmaceutical compositions containing them
IL43000A0 (en) Novel biphenylyl-furans,their preparation and pharmaceutical compositions containing them
IL42435A0 (en) Novel diaminoacridine derivatives,their preparation and pharmaceutical compositions containing them
IL41294A0 (en) 15-oxasteroids,their manufacture and pharmaceutical compositions containing them
IL43029A0 (en) Novel nucleosides,their preparation and pharmaceutical compositions containing them