IL41758A - Alpha-aminoalkyl 4-hydroxy-3-alkylsulfonyl-methylbenzyl alcohols - Google Patents
Alpha-aminoalkyl 4-hydroxy-3-alkylsulfonyl-methylbenzyl alcoholsInfo
- Publication number
- IL41758A IL41758A IL41758A IL4175873A IL41758A IL 41758 A IL41758 A IL 41758A IL 41758 A IL41758 A IL 41758A IL 4175873 A IL4175873 A IL 4175873A IL 41758 A IL41758 A IL 41758A
- Authority
- IL
- Israel
- Prior art keywords
- hydroxy
- chemical compound
- hydrogen
- methyl
- cycloalkyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 claims abstract 10
- 125000000217 alkyl group Chemical group 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- WVDDGKGOMKODPV-UHFFFAOYSA-N hydroxymethyl benzene Natural products OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims 5
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 2
- 235000019445 benzyl alcohol Nutrition 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 150000002431 hydrogen Chemical group 0.000 claims 2
- -1 (t-butylaminomethyl) -4-hydroxy-3- (methylsulfonylmethyl)benzyl Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- LAMHAMBOLINJML-UHFFFAOYSA-N 1-[3-(chloromethyl)-4-hydroxyphenyl]ethanone Chemical compound CC(=O)C1=CC=C(O)C(CCl)=C1 LAMHAMBOLINJML-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 125000004981 cycloalkylmethyl group Chemical group 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23617772A | 1972-03-20 | 1972-03-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL41758A0 IL41758A0 (en) | 1973-05-31 |
| IL41758A true IL41758A (en) | 1976-03-31 |
Family
ID=22888442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL41758A IL41758A (en) | 1972-03-20 | 1973-03-13 | Alpha-aminoalkyl 4-hydroxy-3-alkylsulfonyl-methylbenzyl alcohols |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5636188B2 (ja) |
| AR (1) | AR196924A1 (ja) |
| AU (1) | AU469666B2 (ja) |
| BE (1) | BE796894A (ja) |
| BR (1) | BR7301986D0 (ja) |
| CA (1) | CA1007662A (ja) |
| CH (1) | CH576435A5 (ja) |
| DE (1) | DE2313625C2 (ja) |
| DK (1) | DK145082C (ja) |
| ES (1) | ES412799A1 (ja) |
| FI (1) | FI58326C (ja) |
| FR (1) | FR2183681B1 (ja) |
| GB (2) | GB1386029A (ja) |
| HU (1) | HU166931B (ja) |
| IE (1) | IE38206B1 (ja) |
| IL (1) | IL41758A (ja) |
| IT (1) | IT1061426B (ja) |
| LU (1) | LU67220A1 (ja) |
| NL (1) | NL7303715A (ja) |
| PH (1) | PH9436A (ja) |
| SE (1) | SE403773B (ja) |
| ZA (1) | ZA731903B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3966770A (en) * | 1975-03-25 | 1976-06-29 | Smithkline Corporation | 4-Hydroxy-α-[(3,4-methylenedioxyphenyl)isopropylaminoethyl]-3-(methylsulfonylmethyl)benzyl alcohol |
| ATE89262T1 (de) * | 1987-03-26 | 1993-05-15 | Ciba Geigy Ag | Neue alpha-aminoacetophenone als photoinitiatoren. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE34545B1 (en) * | 1969-10-01 | 1975-06-11 | Continental Pharma | Amino-alcohols,their salts and process for preparing the same |
| ZA723611B (en) * | 1971-06-01 | 1973-03-28 | Smith Kline French Lab | N,n'-bis(2-(3-substituted-4-hydroxyphenyl)-ethyl or-2-hydroxyethyl)-polymethylene-diamines |
-
1973
- 1973-03-06 GB GB2471474A patent/GB1386029A/en not_active Expired
- 1973-03-06 GB GB1076873A patent/GB1386028A/en not_active Expired
- 1973-03-13 IL IL41758A patent/IL41758A/en unknown
- 1973-03-13 IE IE409/73A patent/IE38206B1/xx unknown
- 1973-03-14 SE SE7303544A patent/SE403773B/xx unknown
- 1973-03-14 FR FR7309051A patent/FR2183681B1/fr not_active Expired
- 1973-03-14 FI FI778/73A patent/FI58326C/fi active
- 1973-03-15 LU LU67220A patent/LU67220A1/xx unknown
- 1973-03-15 JP JP3048873A patent/JPS5636188B2/ja not_active Expired
- 1973-03-15 IT IT21683/73A patent/IT1061426B/it active
- 1973-03-15 CA CA166,212A patent/CA1007662A/en not_active Expired
- 1973-03-15 HU HUSI1298A patent/HU166931B/hu unknown
- 1973-03-15 AR AR247078A patent/AR196924A1/es active
- 1973-03-15 DK DK139673A patent/DK145082C/da active
- 1973-03-16 BE BE128895A patent/BE796894A/xx not_active IP Right Cessation
- 1973-03-16 NL NL7303715A patent/NL7303715A/xx unknown
- 1973-03-16 PH PH14433*UA patent/PH9436A/en unknown
- 1973-03-16 AU AU53410/73A patent/AU469666B2/en not_active Expired
- 1973-03-17 ES ES412799A patent/ES412799A1/es not_active Expired
- 1973-03-19 CH CH396473A patent/CH576435A5/xx not_active IP Right Cessation
- 1973-03-19 DE DE2313625A patent/DE2313625C2/de not_active Expired
- 1973-03-19 ZA ZA731903A patent/ZA731903B/xx unknown
- 1973-03-20 BR BR731986A patent/BR7301986D0/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE38206L (en) | 1973-09-20 |
| NL7303715A (ja) | 1973-09-24 |
| PH9436A (en) | 1975-11-26 |
| DE2313625A1 (de) | 1973-10-25 |
| HU166931B (ja) | 1975-06-28 |
| IL41758A0 (en) | 1973-05-31 |
| GB1386028A (en) | 1975-03-05 |
| FR2183681B1 (ja) | 1976-10-22 |
| IE38206B1 (en) | 1978-01-18 |
| JPS5636188B2 (ja) | 1981-08-22 |
| ES412799A1 (es) | 1976-06-01 |
| FI58326C (fi) | 1981-01-12 |
| FI58326B (fi) | 1980-09-30 |
| SE403773B (sv) | 1978-09-04 |
| AR196924A1 (es) | 1974-02-28 |
| ZA731903B (en) | 1974-01-30 |
| FR2183681A1 (ja) | 1973-12-21 |
| LU67220A1 (ja) | 1973-05-22 |
| CA1007662A (en) | 1977-03-29 |
| BR7301986D0 (pt) | 1974-07-25 |
| CH576435A5 (ja) | 1976-06-15 |
| IT1061426B (it) | 1983-02-28 |
| DK145082C (da) | 1983-03-21 |
| GB1386029A (en) | 1975-03-05 |
| DE2313625C2 (de) | 1986-03-13 |
| JPS4911846A (ja) | 1974-02-01 |
| AU469666B2 (en) | 1976-02-19 |
| BE796894A (fr) | 1973-09-17 |
| AU5341073A (en) | 1974-09-19 |
| DK145082B (da) | 1982-08-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU538424B2 (en) | Piperazino phenylindane | |
| GB1173227A (en) | Amino-Isoquinolines | |
| IL41758A (en) | Alpha-aminoalkyl 4-hydroxy-3-alkylsulfonyl-methylbenzyl alcohols | |
| GB1289240A (ja) | ||
| GB1174880A (en) | Derivatives of alpha-Piperazinophenylacetonitrile and process for manufacture of same | |
| ES363591A1 (es) | Un procedimiento para la produccion de derivados de fenile-tilamina. | |
| GB1431712A (en) | Benzomorphan derivatives | |
| GB1181295A (en) | Improvements in or relating to Naphthalene Derivatives and the Manufacture Thereof | |
| GB1245155A (en) | NOVEL 5-SUBSTITUTED-gamma-CARBOLINE DERIVATIVES AND THE SALTS THEREOF | |
| SE7408868L (ja) | ||
| GB1202110A (en) | Novel quinoline derivatives and their preparation | |
| GB1173809A (en) | N-Substituted Nor-Morphines | |
| IE35223L (en) | Bis-basic ethers of 2, 6- and 2, 7-dihydroxy-anthraquinones | |
| GB1503626A (en) | Substituted piperazine derivative its preparation and compositions containing it | |
| JPS5527133A (en) | Drug comprising organosilicon compound as main constituent | |
| GB1310779A (en) | N-pyridylalkyl-beta-alkoxy-beta-trifluoromethylphenalkylamines | |
| GB1317399A (en) | Pyridoindole derivatives | |
| IE39587B1 (en) | Antibacterial compositions | |
| GB1377610A (en) | 5-piperidine-4-spiro- oxazolidinones method for their preparation and applications thereof | |
| GB1280244A (en) | Serum triglyceride-lowering compositions | |
| GB1425560A (en) | 1-substituted-4-benzamido-piperidines and methods for their preparation | |
| IE32514B1 (en) | Synthesis of adamantyl compounds | |
| GB1243186A (en) | Improvements in or relating to mandelamidine derivatives | |
| GB1169807A (en) | p-Chlorobenzyl Compounds and their Serotonin Lowering Ability | |
| GB1427559A (en) | 2-substituted 6,7-benzomorphan derivatives and salts thereof |