IL35729A - 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL35729A
IL35729A IL35729A IL3572970A IL35729A IL 35729 A IL35729 A IL 35729A IL 35729 A IL35729 A IL 35729A IL 3572970 A IL3572970 A IL 3572970A IL 35729 A IL35729 A IL 35729A
Authority
IL
Israel
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
IL35729A
Other languages
English (en)
Other versions
IL35729A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL35729A0 publication Critical patent/IL35729A0/xx
Publication of IL35729A publication Critical patent/IL35729A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL35729A 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them IL35729A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (2)

Publication Number Publication Date
IL35729A0 IL35729A0 (en) 1971-01-28
IL35729A true IL35729A (en) 1974-01-14

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
IL35729A IL35729A (en) 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US3661908A (pm)
BE (1) BE759493A (pm)
BG (2) BG17799A3 (pm)
CA (1) CA926865A (pm)
CH (3) CH567029A5 (pm)
DK (1) DK128781B (pm)
FR (1) FR2073416B1 (pm)
GB (1) GB1321316A (pm)
IE (1) IE34765B1 (pm)
IL (1) IL35729A (pm)
NL (1) NL7017210A (pm)
NO (1) NO129954B (pm)
SE (1) SE377938B (pm)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
AU2007243457B2 (en) 2006-04-26 2012-02-23 F. Hoffmann-La Roche Ag Pharmaceutical compounds
WO2007127183A1 (en) * 2006-04-26 2007-11-08 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and pharmaceutical compositions containing them
DE602007007323D1 (de) 2006-04-26 2010-08-05 Hoffmann La Roche Thienoä3,2-düpyrimidin-derivat geeignet als pi3k inhibitor
ZA200904531B (en) * 2006-12-07 2010-09-29 Hoffmann La Roche Phosphoinositide 3-kinase inhibitor compounds and methods of use
CL2007003520A1 (es) * 2006-12-07 2008-08-22 Piramed Ltd Genentech Inc Compuestos derivados de heterociclos sustituidos con morfolina, inhibidores de la actividad pi3 quinasa; composicion farmaceutica que comprende a dichos compuestos; kit farmaceutico; y su uso para el tratamiento profilactico o terapeutico del cancer.
WO2008152390A1 (en) * 2007-06-12 2008-12-18 F.Hoffmann-La Roche Ag Thiazoliopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
CN101932587A (zh) * 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
CN101909631B (zh) 2007-10-25 2012-09-12 健泰科生物技术公司 制备噻吩并嘧啶化合物的方法
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CN102369011A (zh) 2009-03-12 2012-03-07 健泰科生物技术公司 用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
SG182247A1 (en) * 2009-05-27 2012-08-30 Hoffmann La Roche Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
US8173650B2 (en) * 2009-05-27 2012-05-08 Genentech, Inc. Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
MX345155B (es) * 2009-10-12 2017-01-18 F Hoffmann-La Roche Ag * Combinaciones de un inhibidor de pi3k y un inhibidor de mek.
RU2012148699A (ru) 2010-04-16 2014-05-27 Дженентек, Инк. Foxo3a как прогностический биомаркер для эффективности ингибитора пути киназы pi3k/акт
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
CA2901126C (en) 2013-02-25 2022-01-25 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant

Also Published As

Publication number Publication date
IL35729A0 (en) 1971-01-28
DK128781B (da) 1974-07-01
BG17800A3 (bg) 1973-12-25
BG17799A3 (bg) 1973-12-25
FR2073416B1 (pm) 1975-04-18
CH567029A5 (pm) 1975-09-30
NO129954B (pm) 1974-06-17
US3661908A (en) 1972-05-09
IE34765B1 (en) 1975-08-06
SE377938B (pm) 1975-08-04
CH559210A5 (pm) 1975-02-28
CA926865A (en) 1973-05-22
CH568324A5 (pm) 1975-10-31
FR2073416A1 (pm) 1971-10-01
GB1321316A (en) 1973-06-27
BE759493A (fr) 1971-05-25
NL7017210A (pm) 1971-05-28
IE34765L (en) 1971-05-26

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