IL323506A - Method for producing a cyclic peptide compound - Google Patents
Method for producing a cyclic peptide compoundInfo
- Publication number
- IL323506A IL323506A IL323506A IL32350625A IL323506A IL 323506 A IL323506 A IL 323506A IL 323506 A IL323506 A IL 323506A IL 32350625 A IL32350625 A IL 32350625A IL 323506 A IL323506 A IL 323506A
- Authority
- IL
- Israel
- Prior art keywords
- crystal
- group
- peptide compound
- formula
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
- C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/52—Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Crystallography & Structural Chemistry (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023069189 | 2023-04-20 | ||
| PCT/JP2024/015529 WO2024219480A1 (ja) | 2023-04-20 | 2024-04-19 | 環状ペプチド化合物の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL323506A true IL323506A (en) | 2025-11-01 |
Family
ID=93152939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL323506A IL323506A (en) | 2023-04-20 | 2025-09-21 | Method for producing a cyclic peptide compound |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP4678652A1 (https=) |
| JP (1) | JPWO2024219480A1 (https=) |
| KR (1) | KR20250174064A (https=) |
| CN (1) | CN120936619A (https=) |
| AU (1) | AU2024257451A1 (https=) |
| IL (1) | IL323506A (https=) |
| MX (1) | MX2025012255A (https=) |
| TW (1) | TW202506706A (https=) |
| WO (1) | WO2024219480A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| CN119751564B (zh) * | 2024-12-05 | 2025-11-11 | 浙江大学 | 一种环肽化合物合成方法及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9506372D0 (en) * | 1995-03-29 | 1995-05-17 | Fujisawa Pharmaceutical Co | New peptide compounds |
| KR20210139366A (ko) | 2019-03-15 | 2021-11-22 | 추가이 세이야쿠 가부시키가이샤 | 방향족 아미노산 유도체의 제조 방법 |
| JPWO2022138891A1 (https=) * | 2020-12-25 | 2022-06-30 | ||
| TW202309065A (zh) * | 2021-05-07 | 2023-03-01 | 日商中外製藥股份有限公司 | 包含n-取代胺基酸殘基之環狀化合物的製造方法 |
| AR125796A1 (es) | 2021-05-07 | 2023-08-16 | Chugai Pharmaceutical Co Ltd | Compuesto cíclico que tiene una acción inhibitoria selectiva en kras sobre hras y nras |
| AU2022270498A1 (en) * | 2021-05-07 | 2023-10-05 | Chugai Seiyaku Kabushiki Kaisha | Preparation containing cyclic peptide compound and method for producing same |
-
2024
- 2024-04-19 JP JP2025515295A patent/JPWO2024219480A1/ja active Pending
- 2024-04-19 AU AU2024257451A patent/AU2024257451A1/en active Pending
- 2024-04-19 CN CN202480025074.2A patent/CN120936619A/zh active Pending
- 2024-04-19 TW TW113114671A patent/TW202506706A/zh unknown
- 2024-04-19 KR KR1020257037736A patent/KR20250174064A/ko active Pending
- 2024-04-19 EP EP24792752.8A patent/EP4678652A1/en active Pending
- 2024-04-19 WO PCT/JP2024/015529 patent/WO2024219480A1/ja not_active Ceased
-
2025
- 2025-09-21 IL IL323506A patent/IL323506A/en unknown
- 2025-10-14 MX MX2025012255A patent/MX2025012255A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2024257451A1 (en) | 2025-10-09 |
| CN120936619A (zh) | 2025-11-11 |
| KR20250174064A (ko) | 2025-12-11 |
| WO2024219480A1 (ja) | 2024-10-24 |
| TW202506706A (zh) | 2025-02-16 |
| JPWO2024219480A1 (https=) | 2024-10-24 |
| EP4678652A1 (en) | 2026-01-14 |
| MX2025012255A (es) | 2025-11-03 |
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