JPWO2022138891A1 - - Google Patents
Info
- Publication number
- JPWO2022138891A1 JPWO2022138891A1 JP2022571664A JP2022571664A JPWO2022138891A1 JP WO2022138891 A1 JPWO2022138891 A1 JP WO2022138891A1 JP 2022571664 A JP2022571664 A JP 2022571664A JP 2022571664 A JP2022571664 A JP 2022571664A JP WO2022138891 A1 JPWO2022138891 A1 JP WO2022138891A1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020217157 | 2020-12-25 | ||
| JP2021078395 | 2021-05-06 | ||
| JP2021177528 | 2021-10-29 | ||
| PCT/JP2021/048093 WO2022138891A1 (ja) | 2020-12-25 | 2021-12-24 | Ｎ－置換－アミノ酸残基を含むペプチド化合物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2022138891A1 true JPWO2022138891A1 (https=) | 2022-06-30 |
| JPWO2022138891A5 JPWO2022138891A5 (https=) | 2025-01-06 |
Family
ID=82157997
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022571664A Pending JPWO2022138891A1 (https=) | 2020-12-25 | 2021-12-24 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240124517A1 (https=) |
| EP (1) | EP4269422A4 (https=) |
| JP (1) | JPWO2022138891A1 (https=) |
| KR (1) | KR20230124935A (https=) |
| TW (1) | TW202235429A (https=) |
| WO (1) | WO2022138891A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202446781A (zh) | 2011-12-28 | 2024-12-01 | 日商中外製藥股份有限公司 | 胜肽化合物之製造方法 |
| KR20250007021A (ko) | 2017-06-09 | 2025-01-13 | 추가이 세이야쿠 가부시키가이샤 | N-치환 아미노산을 포함하는 펩타이드의 합성 방법 |
| EP3878836B1 (en) | 2018-11-07 | 2025-07-23 | Chugai Seiyaku Kabushiki Kaisha | O-substituted serine derivative production method |
| EP4056580A4 (en) | 2019-11-07 | 2023-12-06 | Chugai Seiyaku Kabushiki Kaisha | METHOD FOR PRODUCING A PEPTIDE COMPOUND COMPRISING A STERICALLY HINDERED AMINO ACID |
| BR112022007535A2 (pt) | 2019-11-07 | 2022-07-12 | Chugai Pharmaceutical Co Ltd | Composto peptídico cíclico tendo ação inibitória de kras |
| US12312379B2 (en) | 2021-05-07 | 2025-05-27 | Chugai Seiyaku Kabushiki Kaisha | Methods for producing cyclic compounds comprising N-substituted amino acid residues |
| JP7823181B2 (ja) | 2022-05-06 | 2026-03-03 | 中外製薬株式会社 | Ｈｒａｓおよびｎｒａｓに対して選択的なｋｒａｓ阻害作用を有する環状化合物 |
| TW202430539A (zh) * | 2022-10-13 | 2024-08-01 | 日商中外製藥股份有限公司 | 包含ｎ－取代胺基酸殘基的環狀胜肽化合物的製造方法 |
| TW202430537A (zh) * | 2022-10-20 | 2024-08-01 | 日商中外製藥股份有限公司 | 環狀胜肽的結晶的製造方法 |
| JPWO2024096023A1 (https=) | 2022-11-01 | 2024-05-10 | ||
| WO2024143514A1 (ja) | 2022-12-28 | 2024-07-04 | 中外製薬株式会社 | 環状ペプチドの精製法及び製造法 |
| CN120936619A (zh) * | 2023-04-20 | 2025-11-11 | 中外制药株式会社 | 用于生产环肽化合物的方法 |
| TW202523345A (zh) | 2023-09-28 | 2025-06-16 | 日商中外製藥股份有限公司 | 使用混合酸酐法的胜肽化合物的製造方法 |
| TW202535901A (zh) | 2023-12-27 | 2025-09-16 | 日商中外製藥股份有限公司 | 使用獨立型縮合劑的胜肽化合物的製造方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006513980A (ja) * | 2002-08-06 | 2006-04-27 | アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | 結合分子 |
| JP2007332042A (ja) * | 2006-06-12 | 2007-12-27 | National Institute Of Advanced Industrial & Technology | ケージドペプチドの合成法 |
| JP2010529957A (ja) * | 2007-05-30 | 2010-09-02 | イーライ リリー アンド カンパニー | 環状ペプチドｃｘｃｒ４アンタゴニスト |
| JP2014162722A (ja) * | 2013-02-21 | 2014-09-08 | Chemical And Biopharmaceutical Labolatories Of Patra Sa | 側鎖結合を介する固相ペプチド合成 |
| WO2018225851A1 (ja) * | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | Ｎ－置換アミノ酸を含むペプチドの合成方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202446781A (zh) | 2011-12-28 | 2024-12-01 | 日商中外製藥股份有限公司 | 胜肽化合物之製造方法 |
| GB201622029D0 (en) | 2016-12-22 | 2017-02-08 | Nederlands Inst Voor Ecologie (Nioo-Knaw) See Scientia Terrae Vzw Nordic Semiconductor Asa | Voltage sampling circuits |
| CN110869544B (zh) | 2017-06-09 | 2024-03-08 | 中外制药株式会社 | 膜透过性高的环状肽化合物及包含其的文库 |
| WO2020122182A1 (ja) | 2018-12-12 | 2020-06-18 | 中外製薬株式会社 | 分子内水素結合可能な官能基を有するアミノ酸とそれらのアミノ酸を含むペプチド化合物、およびそれらの製造方法 |
-
2021
- 2021-12-24 WO PCT/JP2021/048093 patent/WO2022138891A1/ja not_active Ceased
- 2021-12-24 TW TW110148606A patent/TW202235429A/zh unknown
- 2021-12-24 EP EP21911028.5A patent/EP4269422A4/en active Pending
- 2021-12-24 JP JP2022571664A patent/JPWO2022138891A1/ja active Pending
- 2021-12-24 US US18/268,737 patent/US20240124517A1/en active Pending
- 2021-12-24 KR KR1020237021960A patent/KR20230124935A/ko active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006513980A (ja) * | 2002-08-06 | 2006-04-27 | アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | 結合分子 |
| JP2007332042A (ja) * | 2006-06-12 | 2007-12-27 | National Institute Of Advanced Industrial & Technology | ケージドペプチドの合成法 |
| JP2010529957A (ja) * | 2007-05-30 | 2010-09-02 | イーライ リリー アンド カンパニー | 環状ペプチドｃｘｃｒ４アンタゴニスト |
| JP2014162722A (ja) * | 2013-02-21 | 2014-09-08 | Chemical And Biopharmaceutical Labolatories Of Patra Sa | 側鎖結合を介する固相ペプチド合成 |
| WO2018225851A1 (ja) * | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | Ｎ－置換アミノ酸を含むペプチドの合成方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022138891A1 (ja) | 2022-06-30 |
| KR20230124935A (ko) | 2023-08-28 |
| EP4269422A4 (en) | 2024-11-27 |
| EP4269422A1 (en) | 2023-11-01 |
| TW202235429A (zh) | 2022-09-16 |
| US20240124517A1 (en) | 2024-04-18 |
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