MX2025012255A - Metodo para producir un compuesto de peptido ciclico - Google Patents

Metodo para producir un compuesto de peptido ciclico

Info

Publication number
MX2025012255A
MX2025012255A MX2025012255A MX2025012255A MX2025012255A MX 2025012255 A MX2025012255 A MX 2025012255A MX 2025012255 A MX2025012255 A MX 2025012255A MX 2025012255 A MX2025012255 A MX 2025012255A MX 2025012255 A MX2025012255 A MX 2025012255A
Authority
MX
Mexico
Prior art keywords
peptide compound
producing
cyclic peptide
cyclization
producing cyclic
Prior art date
Application number
MX2025012255A
Other languages
English (en)
Spanish (es)
Inventor
Takahiro Horibe
Junichi Shiina
Yinli Wang
Yuuki INOMATA
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2025012255A publication Critical patent/MX2025012255A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • C07K1/306Extraction; Separation; Purification by precipitation by crystallization
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/52Cyclic peptides containing at least one abnormal peptide link with only normal peptide links in the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
MX2025012255A 2023-04-20 2025-10-14 Metodo para producir un compuesto de peptido ciclico MX2025012255A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2023069189 2023-04-20
PCT/JP2024/015529 WO2024219480A1 (ja) 2023-04-20 2024-04-19 環状ペプチド化合物の製造方法

Publications (1)

Publication Number Publication Date
MX2025012255A true MX2025012255A (es) 2025-11-03

Family

ID=93152939

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2025012255A MX2025012255A (es) 2023-04-20 2025-10-14 Metodo para producir un compuesto de peptido ciclico

Country Status (9)

Country Link
EP (1) EP4678652A1 (https=)
JP (1) JPWO2024219480A1 (https=)
KR (1) KR20250174064A (https=)
CN (1) CN120936619A (https=)
AU (1) AU2024257451A1 (https=)
IL (1) IL323506A (https=)
MX (1) MX2025012255A (https=)
TW (1) TW202506706A (https=)
WO (1) WO2024219480A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
US20250375445A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer
CN119751564B (zh) * 2024-12-05 2025-11-11 浙江大学 一种环肽化合物合成方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506372D0 (en) * 1995-03-29 1995-05-17 Fujisawa Pharmaceutical Co New peptide compounds
KR20210139366A (ko) 2019-03-15 2021-11-22 추가이 세이야쿠 가부시키가이샤 방향족 아미노산 유도체의 제조 방법
JPWO2022138891A1 (https=) * 2020-12-25 2022-06-30
TW202309065A (zh) * 2021-05-07 2023-03-01 日商中外製藥股份有限公司 包含n-取代胺基酸殘基之環狀化合物的製造方法
AR125796A1 (es) 2021-05-07 2023-08-16 Chugai Pharmaceutical Co Ltd Compuesto cíclico que tiene una acción inhibitoria selectiva en kras sobre hras y nras
AU2022270498A1 (en) * 2021-05-07 2023-10-05 Chugai Seiyaku Kabushiki Kaisha Preparation containing cyclic peptide compound and method for producing same

Also Published As

Publication number Publication date
IL323506A (en) 2025-11-01
AU2024257451A1 (en) 2025-10-09
CN120936619A (zh) 2025-11-11
KR20250174064A (ko) 2025-12-11
WO2024219480A1 (ja) 2024-10-24
TW202506706A (zh) 2025-02-16
JPWO2024219480A1 (https=) 2024-10-24
EP4678652A1 (en) 2026-01-14

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