IL31990A - Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing same - Google Patents
Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing sameInfo
- Publication number
- IL31990A IL31990A IL31990A IL3199069A IL31990A IL 31990 A IL31990 A IL 31990A IL 31990 A IL31990 A IL 31990A IL 3199069 A IL3199069 A IL 3199069A IL 31990 A IL31990 A IL 31990A
- Authority
- IL
- Israel
- Prior art keywords
- pyridyl
- preparation
- pharmaceutical compositions
- compositions containing
- containing same
- Prior art date
Links
- ZAAIEOSUVDRLGD-UHFFFAOYSA-N 3-pyridin-2-yl-1,2,4-oxadiazole Chemical class O1C=NC(C=2N=CC=CC=2)=N1 ZAAIEOSUVDRLGD-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000796 | 1968-04-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL31990A0 IL31990A0 (en) | 1969-06-25 |
| IL31990A true IL31990A (en) | 1974-05-16 |
Family
ID=10994349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL31990A IL31990A (en) | 1968-04-26 | 1969-04-08 | Pyridyl 1,2,4-oxadiazole derivatives,process for the preparation thereof and pharmaceutical compositions containing same |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3647809A (pl) |
| JP (1) | JPS4824394B1 (pl) |
| AT (2) | AT292727B (pl) |
| BE (1) | BE732131A (pl) |
| BR (1) | BR6908381D0 (pl) |
| CA (1) | CA954858A (pl) |
| CH (2) | CH542232A (pl) |
| DE (1) | DE1920037A1 (pl) |
| FR (1) | FR2007529B1 (pl) |
| GB (1) | GB1271302A (pl) |
| IL (1) | IL31990A (pl) |
| NL (1) | NL6906401A (pl) |
| NO (1) | NO124253B (pl) |
| PL (1) | PL79435B1 (pl) |
| SE (1) | SE368576B (pl) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853893A (en) * | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
| HU177086B (en) * | 1975-06-09 | 1981-07-28 | Eszakmagyar Vegyimuevek | Herbicide and fungicide preparation containing substituted 1,2,4-oxadiazolidin-3-one derivatives |
| JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な１，２，４−オキサジアゾ−ル誘導体 |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US6660753B2 (en) * | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| EP1582519A3 (en) * | 1999-08-19 | 2005-12-21 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| JP3790472B2 (ja) * | 1999-08-19 | 2006-06-28 | エヌピーエス ファーマシューティカルズ インコーポレーテッド | ヘテロ多環式化合物および代謝型グルタミン酸受容体アンタゴニストとしてのその使用 |
| SI1379525T1 (sl) * | 2001-02-21 | 2007-12-31 | Astrazeneca Ab | Heteropoliciklične spojine in njihova uporaba kot antagonisti metabotropnih glutamatnih receptorjev |
| US7074809B2 (en) | 2002-08-09 | 2006-07-11 | Astrazeneca Ab | Compounds |
| AU2004229392A1 (en) * | 2003-04-09 | 2004-10-28 | Exelixis, Inc. | Tie-2 modulators and methods of use |
| JP2006528980A (ja) * | 2003-05-15 | 2006-12-28 | メルク エンド カムパニー インコーポレーテッド | Ｓ１ｐ受容体作働薬としての３−（２−アミノ−１−アザシクロ）−５−アリール−１，２，４−オキサジアゾール類 |
| US20060189661A1 (en) * | 2003-11-03 | 2006-08-24 | Wagenen Bradford V | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| WO2005060961A2 (en) * | 2003-12-18 | 2005-07-07 | Astrazeneca Ab | Treatment of transient lower esophageal sphincter relaxations (tlesrs) and gastro-esophageal reflux disease (gerd) |
| AU2004303604B2 (en) * | 2003-12-24 | 2011-03-24 | Prosidion Limited | Heterocyclic derivatives as GPCR receptor agonists |
| WO2005077368A2 (en) * | 2004-02-03 | 2005-08-25 | Astrazeneca Ab | Treatment of gastro-esophageal reflux disease (gerd) |
| KR20080000622A (ko) * | 2005-04-26 | 2008-01-02 | 뉴로서치 에이/에스 | 신규한 옥사디아졸 유도체 및 이의 의학적 용도 |
| IL169855A (en) * | 2005-07-25 | 2014-05-28 | Elta Systems Ltd | A system and method for locating a receiver location |
| ES2545178T3 (es) | 2005-07-26 | 2015-09-09 | Bial-Portela & Ca, S.A. | Derivados de nitrocatecol como inhibidores de la COMT |
| EP1845097A1 (en) * | 2006-04-10 | 2007-10-17 | Portela & Ca., S.A. | Oxadiazole derivatives as COMT inhibitors |
| CN101511827B (zh) * | 2006-09-07 | 2012-02-01 | 埃科特莱茵药品有限公司 | 作为免疫调制剂的吡啶-4-基衍生物 |
| CA2661315C (en) * | 2006-09-08 | 2015-11-24 | Actelion Pharmaceuticals Ltd | Pyridin-3-yl derivatives as immunomodulating agents |
| DK2481410T3 (en) | 2007-01-31 | 2016-10-24 | Bial - Portela & Ca S A | Nitrocatecholderivater as COMT inhibitors administered in a specific dosage regimen |
| SI2125797T1 (sl) * | 2007-03-16 | 2014-03-31 | Actelion Pharmaceuticals Ltd. | Derivati amino-piridina kot agonisti receptorja s1p1/edg1 |
| BRPI0815190A2 (pt) * | 2007-08-17 | 2015-03-31 | Actelion Pharmaceuticals Ltd | Composto derivado de piridina, composição farmacêutica que o compreende e uso do mesmo |
| MX2010009043A (es) * | 2008-02-28 | 2010-10-25 | Bial Portela & Ca Sa | Composicion farmaceutica para farmacos poco solubles. |
| EP2262799B1 (en) * | 2008-03-06 | 2012-07-04 | Actelion Pharmaceuticals Ltd. | Pyridine compounds |
| NZ588438A (en) * | 2008-03-07 | 2012-05-25 | Actelion Pharmaceuticals Ltd | Pyridin-2-yl oxadiazole derivatives as immunomodulating agents |
| CL2009000628A1 (es) | 2008-03-17 | 2010-04-09 | Bial Portela & Companhia S A | Forma cristalina de 5-[3-(2,5-dicloro-4,6-dimetil-1-oxi-piridin-3-il)-[1,2,4]oxadiazol-5-il]-3-nitrobenceno-1,2-diol, composicion farmaceutica que la comprende, proceso para obtenerla y su uso para tratar trastornos del animo, enfermedad de parkinson y trastornos parkinsonianos, alteraciones gastrointestinales, entre otros. |
| DK2291080T3 (en) | 2008-05-14 | 2015-12-07 | Scripps Research Inst | Novel modulator of sphingosinphosphatreceptorer |
| EP2396321B1 (en) | 2009-02-10 | 2015-05-06 | Monsanto Technology LLC | Compositions and methods for controlling nematodes |
| CN102438595B (zh) * | 2009-04-01 | 2016-04-27 | 巴尔-波特拉及康邦亚股份有限公司 | 包括硝基儿茶酚衍生物的药物制剂及其制备方法 |
| KR20210009441A (ko) | 2009-04-01 | 2021-01-26 | 바이알 - 포르텔라 앤드 씨에이 에스에이 | 니트로카테콜 유도체를 포함하는 제약 제제 및 그의 제조 방법 |
| EP2454255B1 (en) | 2009-07-16 | 2013-11-06 | Actelion Pharmaceuticals Ltd. | Pyridin-4-yl derivatives as s1p1/edg1 agonists |
| ES2544086T3 (es) | 2011-01-19 | 2015-08-27 | Actelion Pharmaceuticals Ltd. | Derivados de 2-metoxi-piridin-4-ilo |
| US20140045900A1 (en) | 2011-02-11 | 2014-02-13 | Bial-Portela & Ca, S.A. | Administration regime for nitrocatechols |
| EP2791134B1 (en) | 2011-12-13 | 2019-09-25 | BIAL - Portela & Cª S.A. | Chemical compound useful as intermediate for preparing a catechol-o-methyltransferase inhibitor |
| CA2901006A1 (en) * | 2013-02-15 | 2014-08-21 | Monsanto Technology Llc | 3,5-disubstituted-4,5-dihydro-1,2,4-oxadiazoles for controlling nematode pests |
| WO2016083863A1 (en) | 2014-11-28 | 2016-06-02 | Bial - Portela & Ca, S.A. | Medicaments for slowing parkinson's disease |
| PH12017502097B1 (en) | 2015-05-20 | 2023-05-05 | Idorsia Pharmaceuticals Ltd | Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL120029C (pl) * | 1959-09-29 | |||
| US3227725A (en) * | 1962-04-17 | 1966-01-04 | Union Carbide Corp | Certain 3,5-disubstituted 1,2,4-oxadiazole compounds |
-
1969
- 1969-04-08 IL IL31990A patent/IL31990A/xx unknown
- 1969-04-08 US US815520A patent/US3647809A/en not_active Expired - Lifetime
- 1969-04-14 GB GB09047/69A patent/GB1271302A/en not_active Expired
- 1969-04-18 AT AT375469A patent/AT292727B/de not_active IP Right Cessation
- 1969-04-18 AT AT815670A patent/AT292728B/de not_active IP Right Cessation
- 1969-04-19 DE DE19691920037 patent/DE1920037A1/de active Pending
- 1969-04-24 CH CH1476972A patent/CH542232A/de not_active IP Right Cessation
- 1969-04-24 CH CH627569A patent/CH540925A/de not_active IP Right Cessation
- 1969-04-24 FR FR696912994A patent/FR2007529B1/fr not_active Expired
- 1969-04-25 BR BR208381/69A patent/BR6908381D0/pt unknown
- 1969-04-25 JP JP44032259A patent/JPS4824394B1/ja active Pending
- 1969-04-25 NO NO1733/69A patent/NO124253B/no unknown
- 1969-04-25 NL NL6906401A patent/NL6906401A/xx unknown
- 1969-04-25 PL PL1969133199A patent/PL79435B1/pl unknown
- 1969-04-25 SE SE05909/69A patent/SE368576B/xx unknown
- 1969-04-25 CA CA049,755A patent/CA954858A/en not_active Expired
- 1969-04-25 BE BE732131D patent/BE732131A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT292727B (de) | 1971-09-10 |
| GB1271302A (en) | 1972-04-19 |
| JPS4824394B1 (pl) | 1973-07-20 |
| NO124253B (pl) | 1972-03-27 |
| PL79435B1 (en) | 1975-06-30 |
| AT292728B (de) | 1971-09-10 |
| CH540925A (de) | 1973-08-31 |
| BR6908381D0 (pt) | 1973-02-08 |
| FR2007529B1 (pl) | 1973-03-16 |
| CH542232A (de) | 1973-11-15 |
| SE368576B (pl) | 1974-07-08 |
| DE1920037A1 (de) | 1970-11-12 |
| IL31990A0 (en) | 1969-06-25 |
| BE732131A (pl) | 1969-10-01 |
| US3647809A (en) | 1972-03-07 |
| CA954858A (en) | 1974-09-17 |
| NL6906401A (pl) | 1969-10-28 |
| FR2007529A1 (pl) | 1970-01-09 |
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