IL312731A - Relaxin-2 fusion protein analogs and methods of using same - Google Patents

Relaxin-2 fusion protein analogs and methods of using same

Info

Publication number
IL312731A
IL312731A IL312731A IL31273124A IL312731A IL 312731 A IL312731 A IL 312731A IL 312731 A IL312731 A IL 312731A IL 31273124 A IL31273124 A IL 31273124A IL 312731 A IL312731 A IL 312731A
Authority
IL
Israel
Prior art keywords
seq
amino acid
acid sequence
position corresponding
use according
Prior art date
Application number
IL312731A
Other languages
English (en)
Hebrew (he)
Original Assignee
Tectonic Therapeutic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tectonic Therapeutic Inc filed Critical Tectonic Therapeutic Inc
Publication of IL312731A publication Critical patent/IL312731A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
IL312731A 2021-11-11 2022-11-11 Relaxin-2 fusion protein analogs and methods of using same IL312731A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163263917P 2021-11-11 2021-11-11
PCT/US2022/079681 WO2023086913A2 (en) 2021-11-11 2022-11-11 Relaxin-2 fusion protein analogs and methods of using same

Publications (1)

Publication Number Publication Date
IL312731A true IL312731A (en) 2024-07-01

Family

ID=86336636

Family Applications (1)

Application Number Title Priority Date Filing Date
IL312731A IL312731A (en) 2021-11-11 2022-11-11 Relaxin-2 fusion protein analogs and methods of using same

Country Status (10)

Country Link
US (1) US12509497B2 (https=)
EP (1) EP4429694A4 (https=)
JP (1) JP2024543455A (https=)
KR (1) KR20240110824A (https=)
CN (1) CN118510536A (https=)
AU (1) AU2022388751A1 (https=)
CA (1) CA3237801A1 (https=)
IL (1) IL312731A (https=)
MX (1) MX2024005654A (https=)
WO (1) WO2023086913A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118510536A (zh) 2021-11-11 2024-08-16 泰克托尼治疗股份有限公司 松弛素-2融合蛋白类似物及其使用方法
AU2024270919A1 (en) 2023-05-18 2026-01-15 Tectonic Operating Company, Inc. Relaxin-2 fusion protein analogs and methods of using same

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WO2013177529A1 (en) 2012-05-24 2013-11-28 Angion Biomedica Corp. Relaxin-like compounds and uses thereof
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AU2024270919A1 (en) * 2023-05-18 2026-01-15 Tectonic Operating Company, Inc. Relaxin-2 fusion protein analogs and methods of using same

Also Published As

Publication number Publication date
WO2023086913A3 (en) 2023-06-22
JP2024543455A (ja) 2024-11-21
KR20240110824A (ko) 2024-07-16
WO2023086913A2 (en) 2023-05-19
CN118510536A (zh) 2024-08-16
US12509497B2 (en) 2025-12-30
MX2024005654A (es) 2024-09-11
EP4429694A2 (en) 2024-09-18
CA3237801A1 (en) 2023-05-19
EP4429694A4 (en) 2025-10-01
AU2022388751A1 (en) 2024-05-30
US20230340058A1 (en) 2023-10-26

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