IL310625A - Methods for using EHMT2 inhibitors in the treatment or prevention of blood disorders - Google Patents

Methods for using EHMT2 inhibitors in the treatment or prevention of blood disorders

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Publication number
IL310625A
IL310625A IL310625A IL31062524A IL310625A IL 310625 A IL310625 A IL 310625A IL 310625 A IL310625 A IL 310625A IL 31062524 A IL31062524 A IL 31062524A IL 310625 A IL310625 A IL 310625A
Authority
IL
Israel
Prior art keywords
halo
optionally substituted
alkyl
independently
cyano
Prior art date
Application number
IL310625A
Other languages
English (en)
Hebrew (he)
Original Assignee
Epizyme Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epizyme Inc filed Critical Epizyme Inc
Publication of IL310625A publication Critical patent/IL310625A/en

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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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