IL307250A - Processes for preparing bicyclic ketone compounds - Google Patents

Processes for preparing bicyclic ketone compounds

Info

Publication number
IL307250A
IL307250A IL307250A IL30725023A IL307250A IL 307250 A IL307250 A IL 307250A IL 307250 A IL307250 A IL 307250A IL 30725023 A IL30725023 A IL 30725023A IL 307250 A IL307250 A IL 307250A
Authority
IL
Israel
Prior art keywords
processes
ketone compounds
bicyclic ketone
making bicyclic
making
Prior art date
Application number
IL307250A
Other languages
English (en)
Hebrew (he)
Inventor
Allen Y Hong
Nicholas Wong
Sean M Kelly
Lauren Elizabeth Sirois
Sara Schwegler
Xin Linghu
Francis Gosselin
Katarzyna Aleksandra Piechowicz
Carmela Molinaro
Dennis Wetzl
Original Assignee
Hoffmann La Roche
Genentech Inc
Allen Y Hong
Nicholas Wong
Sean M Kelly
Lauren Elizabeth Sirois
Sara Schwegler
Xin Linghu
Francis Gosselin
Katarzyna Aleksandra Piechowicz
Carmela Molinaro
Dennis Wetzl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Genentech Inc, Allen Y Hong, Nicholas Wong, Sean M Kelly, Lauren Elizabeth Sirois, Sara Schwegler, Xin Linghu, Francis Gosselin, Katarzyna Aleksandra Piechowicz, Carmela Molinaro, Dennis Wetzl filed Critical Hoffmann La Roche
Publication of IL307250A publication Critical patent/IL307250A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/50Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
IL307250A 2021-04-02 2022-04-01 Processes for preparing bicyclic ketone compounds IL307250A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163170422P 2021-04-02 2021-04-02
PCT/US2022/022997 WO2022212809A1 (en) 2021-04-02 2022-04-01 Processes for making bicyclic ketone compounds

Publications (1)

Publication Number Publication Date
IL307250A true IL307250A (en) 2023-11-01

Family

ID=81385014

Family Applications (1)

Application Number Title Priority Date Filing Date
IL307250A IL307250A (en) 2021-04-02 2022-04-01 Processes for preparing bicyclic ketone compounds

Country Status (13)

Country Link
US (1) US20240034739A1 (https=)
EP (1) EP4313986A1 (https=)
JP (1) JP2024513394A (https=)
KR (1) KR20230165238A (https=)
CN (1) CN117098762A (https=)
AR (1) AR125294A1 (https=)
AU (1) AU2022246900A1 (https=)
BR (1) BR112023020229A2 (https=)
CA (1) CA3214802A1 (https=)
IL (1) IL307250A (https=)
MX (1) MX2023011482A (https=)
TW (1) TW202304921A (https=)
WO (1) WO2022212809A1 (https=)

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3155107B2 (ja) 1993-01-12 2001-04-09 ダイセル化学工業株式会社 光学活性4−ハロ−3−ヒドロキシ酪酸エステルの製造方法
JPH08336393A (ja) 1995-04-13 1996-12-24 Mitsubishi Chem Corp 光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
JP3915015B2 (ja) 1995-08-22 2007-05-16 味の素株式会社 光学活性2−ヒドロキシ−4−アリール酪酸またはそのエステルの製造方法
CA2234913A1 (en) * 1995-10-18 1997-04-24 Paul E. Finke Cyclopentyl tachykinin receptor antagonists
US5891685A (en) 1996-06-03 1999-04-06 Mitsubishi Chemical Corporation Method for producing ester of (S)-γ-halogenated-β-hydroxybutyric acid
DE19857302C2 (de) 1998-12-14 2000-10-26 Forschungszentrum Juelich Gmbh Verfahren zur enantioselektiven Reduktion von 3,5-Dioxocarbonsäuren, deren Salze und Ester
JP4510351B2 (ja) 1999-12-03 2010-07-21 株式会社カネカ 新規カルボニル還元酵素、その遺伝子、およびその利用法
AU2007201854A1 (en) * 2000-10-17 2007-05-17 Merck Serono Sa Pharmaceutically active sulfanilide derivatives
MXPA03008437A (es) 2001-03-22 2004-01-29 Bristol Myers Squibb Co Reduccion estereoselectiva de acetofenona substituida.
JP4394647B2 (ja) 2003-12-02 2010-01-06 メルシャン株式会社 光学活性テトラヒドロチオフェン誘導体の製造方法、および、光学活性テトラヒドロチオフェン−3−オールの晶析方法
WO2006130657A2 (en) 2005-05-31 2006-12-07 Bristol-Myers Squibb Company Stereoselective reduction process for the preparation of pyrrolotriazine compounds
EP2115130B1 (en) 2007-02-08 2011-08-03 Codexis, Inc. Ketoreductases and uses thereof
JP2010070502A (ja) * 2008-09-19 2010-04-02 Daiichi Sankyo Co Ltd 抗真菌作用トリアゾロピリジン誘導体
CA2753696A1 (en) * 2009-02-26 2010-09-02 Noritaka Kitazawa Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors
TWI637951B (zh) 2013-02-15 2018-10-11 英商葛蘭素史克智慧財產發展有限公司 作為激酶抑制劑之雜環醯胺類
EP3317269B1 (en) * 2015-07-02 2022-09-21 F. Hoffmann-La Roche AG Bicyclic lactams as receptor-interacting protein-1 (rip1) kinase inhibitors for treating e.g. inflammatory diseases
US11071721B2 (en) * 2016-12-02 2021-07-27 Genentech, Inc. Bicyclic amide compounds and methods of use thereof
BR112020000771A2 (pt) * 2017-07-14 2020-07-14 F. Hoffmann-La Roche Ag compostos de cetona bicíclica e métodos de uso dos mesmos
RU2020114670A (ru) * 2017-10-11 2021-11-12 Ф. Хоффманн-Ля Рош Аг Бициклические соединения для применения в качестве ингибиторов rip1 киназы
CN113302193A (zh) * 2019-01-11 2021-08-24 豪夫迈·罗氏有限公司 双环吡咯并三唑酮化合物及其使用方法
CN111606890A (zh) * 2019-02-26 2020-09-01 微境生物医药科技(上海)有限公司 含丙烯酰基的核转运调节剂及其用途

Also Published As

Publication number Publication date
AR125294A1 (es) 2023-07-05
CA3214802A1 (en) 2022-10-06
MX2023011482A (es) 2023-10-03
BR112023020229A2 (pt) 2023-11-14
EP4313986A1 (en) 2024-02-07
AU2022246900A1 (en) 2023-09-14
CN117098762A (zh) 2023-11-21
KR20230165238A (ko) 2023-12-05
TW202304921A (zh) 2023-02-01
JP2024513394A (ja) 2024-03-25
AU2022246900A8 (en) 2023-09-21
US20240034739A1 (en) 2024-02-01
WO2022212809A1 (en) 2022-10-06

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