AU2022246900A8 - Processes for making bicyclic ketone compounds - Google Patents
Processes for making bicyclic ketone compounds Download PDFInfo
- Publication number
- AU2022246900A8 AU2022246900A8 AU2022246900A AU2022246900A AU2022246900A8 AU 2022246900 A8 AU2022246900 A8 AU 2022246900A8 AU 2022246900 A AU2022246900 A AU 2022246900A AU 2022246900 A AU2022246900 A AU 2022246900A AU 2022246900 A8 AU2022246900 A8 AU 2022246900A8
- Authority
- AU
- Australia
- Prior art keywords
- processes
- ketone compounds
- bicyclic ketone
- making bicyclic
- making
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- -1 bicyclic ketone compounds Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Processes are provided herein for the preparation of a bicyclic ketone compound of formula (I), or a stereoisomer thereof: or a pharmaceutically acceptable salt thereof, wherein R
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163170422P | 2021-04-02 | 2021-04-02 | |
US63/170,422 | 2021-04-02 | ||
PCT/US2022/022997 WO2022212809A1 (en) | 2021-04-02 | 2022-04-01 | Processes for making bicyclic ketone compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2022246900A1 AU2022246900A1 (en) | 2023-09-14 |
AU2022246900A8 true AU2022246900A8 (en) | 2023-09-21 |
Family
ID=81385014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2022246900A Pending AU2022246900A1 (en) | 2021-04-02 | 2022-04-01 | Processes for making bicyclic ketone compounds |
Country Status (12)
Country | Link |
---|---|
US (1) | US20240034739A1 (en) |
EP (1) | EP4313986A1 (en) |
JP (1) | JP2024513394A (en) |
KR (1) | KR20230165238A (en) |
CN (1) | CN117098762A (en) |
AR (1) | AR125294A1 (en) |
AU (1) | AU2022246900A1 (en) |
BR (1) | BR112023020229A2 (en) |
CA (1) | CA3214802A1 (en) |
IL (1) | IL307250A (en) |
TW (1) | TW202304921A (en) |
WO (1) | WO2022212809A1 (en) |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3155107B2 (en) | 1993-01-12 | 2001-04-09 | ダイセル化学工業株式会社 | Method for producing optically active 4-halo-3-hydroxybutyrate |
JPH08336393A (en) | 1995-04-13 | 1996-12-24 | Mitsubishi Chem Corp | Production of optically active gamma-substituted-beta-hydroxybutyric ester |
JP3915015B2 (en) | 1995-08-22 | 2007-05-16 | 味の素株式会社 | Process for producing optically active 2-hydroxy-4-arylbutyric acid or ester thereof |
US5891685A (en) | 1996-06-03 | 1999-04-06 | Mitsubishi Chemical Corporation | Method for producing ester of (S)-γ-halogenated-β-hydroxybutyric acid |
DE19857302C2 (en) | 1998-12-14 | 2000-10-26 | Forschungszentrum Juelich Gmbh | Process for the enantioselective reduction of 3,5-dioxocarboxylic acids, their salts and esters |
CZ20012792A3 (en) | 1999-12-03 | 2002-03-13 | Kaneka Corporation | Polypeptide, polynucleotide encoding polypeptide, expression vector, transformant and preparation process |
CZ20032496A3 (en) | 2001-03-22 | 2003-12-17 | Bristol-Myers Squibb Company | Stereoselective reduction process of substituted acetophenone |
US20080050787A1 (en) | 2003-12-02 | 2008-02-28 | Hazuki Nagai | Method for Manufacturing Optically Active Tetrahydrothiophene Derivative and Method for Crystallization of Optically Active Tetrahydrothiophene-3-Ol |
US7393667B2 (en) | 2005-05-31 | 2008-07-01 | Bristol-Myers Squibb Company | Stereoselective reduction process for the preparation of pyrrolotriazine compounds |
US7820421B2 (en) | 2007-02-08 | 2010-10-26 | Codexis, Inc. | Ketoreductases and uses thereof |
TWI648273B (en) | 2013-02-15 | 2019-01-21 | 英商葛蘭素史克智慧財產發展有限公司 | Heterocyclic amides as kinase inhibitors (III) |
CA2988601C (en) | 2015-07-02 | 2021-12-07 | F. Hoffmann-La Roche Ag | Bicyclic lactams and methods of use thereof |
TW201831478A (en) * | 2016-12-02 | 2018-09-01 | 瑞士商赫孚孟拉羅股份公司 | Bicyclic amide compounds and methods of use thereof |
AR112274A1 (en) | 2017-07-14 | 2019-10-09 | Hoffmann La Roche | BICYCLIC KETONE COMPOUNDS AND THEIR METHODS OF USE |
-
2022
- 2022-04-01 IL IL307250A patent/IL307250A/en unknown
- 2022-04-01 TW TW111112842A patent/TW202304921A/en unknown
- 2022-04-01 WO PCT/US2022/022997 patent/WO2022212809A1/en active Application Filing
- 2022-04-01 EP EP22718464.5A patent/EP4313986A1/en active Pending
- 2022-04-01 AU AU2022246900A patent/AU2022246900A1/en active Pending
- 2022-04-01 AR ARP220100830A patent/AR125294A1/en unknown
- 2022-04-01 KR KR1020237033599A patent/KR20230165238A/en unknown
- 2022-04-01 JP JP2023560507A patent/JP2024513394A/en active Pending
- 2022-04-01 BR BR112023020229A patent/BR112023020229A2/en unknown
- 2022-04-01 CN CN202280025356.3A patent/CN117098762A/en active Pending
- 2022-04-01 CA CA3214802A patent/CA3214802A1/en active Pending
-
2023
- 2023-10-02 US US18/479,596 patent/US20240034739A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2022246900A1 (en) | 2023-09-14 |
CN117098762A (en) | 2023-11-21 |
KR20230165238A (en) | 2023-12-05 |
IL307250A (en) | 2023-11-01 |
WO2022212809A1 (en) | 2022-10-06 |
BR112023020229A2 (en) | 2023-11-14 |
EP4313986A1 (en) | 2024-02-07 |
TW202304921A (en) | 2023-02-01 |
AR125294A1 (en) | 2023-07-05 |
JP2024513394A (en) | 2024-03-25 |
CA3214802A1 (en) | 2022-10-06 |
US20240034739A1 (en) | 2024-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TH | Corrigenda |
Free format text: IN VOL 57 , NO 36 , PAGE(S) 5210 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE - NAME INDEX UNDER THE NAME GENENTECH, INC., APPLICATION NO. 2022246900, UNDER INID (71) ADD CO-APPLICANT F. HOFFMANN-LA ROCHE AG. |