IL305337A - S1p modulator immediate release dosage regimen - Google Patents
S1p modulator immediate release dosage regimenInfo
- Publication number
- IL305337A IL305337A IL305337A IL30533723A IL305337A IL 305337 A IL305337 A IL 305337A IL 305337 A IL305337 A IL 305337A IL 30533723 A IL30533723 A IL 30533723A IL 305337 A IL305337 A IL 305337A
- Authority
- IL
- Israel
- Prior art keywords
- siponimod
- day
- dosage form
- patient
- treatment
- Prior art date
Links
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- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461977816P | 2014-04-10 | 2014-04-10 | |
| PCT/IB2015/052550 WO2015155709A1 (en) | 2014-04-10 | 2015-04-08 | S1p modulator immediate release dosage regimen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL305337A true IL305337A (en) | 2023-10-01 |
Family
ID=52988364
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL305337A IL305337A (en) | 2014-04-10 | 2015-04-08 | S1p modulator immediate release dosage regimen |
| IL247986A IL247986A0 (en) | 2014-04-10 | 2016-09-22 | A therapeutic regimen containing an immediate release dose of an s1p modulator |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL247986A IL247986A0 (en) | 2014-04-10 | 2016-09-22 | A therapeutic regimen containing an immediate release dose of an s1p modulator |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US20170027907A1 (enExample) |
| EP (3) | EP3831378A1 (enExample) |
| JP (1) | JP6674903B2 (enExample) |
| KR (2) | KR20160141841A (enExample) |
| CN (2) | CN116650467A (enExample) |
| AU (2) | AU2015246036A1 (enExample) |
| CA (1) | CA2943598C (enExample) |
| CL (1) | CL2016002562A1 (enExample) |
| IL (2) | IL305337A (enExample) |
| MX (1) | MX2016013245A (enExample) |
| PH (1) | PH12016501965A1 (enExample) |
| RU (2) | RU2715734C2 (enExample) |
| SG (1) | SG11201607894RA (enExample) |
| TW (1) | TW201622721A (enExample) |
| WO (1) | WO2015155709A1 (enExample) |
| ZA (1) | ZA201606519B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2699580T3 (enExample) | 2014-01-24 | 2018-02-24 | ||
| SG11201607894RA (en) * | 2014-04-10 | 2016-10-28 | Novartis Ag | S1p modulator immediate release dosage regimen |
| US11629124B2 (en) | 2017-03-09 | 2023-04-18 | Novartis Ag | Solid forms comprising an oxime ether compound, compositions and methods of use thereof |
| US11434200B2 (en) | 2017-03-09 | 2022-09-06 | Novartis Ag | Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof |
| US20200316021A1 (en) * | 2017-09-29 | 2020-10-08 | Novartis Ag | Dosing Regimen of Siponimod |
| US20200306222A1 (en) * | 2017-09-29 | 2020-10-01 | Novartis Ag | Dosing Regimen of Siponimod |
| SI3758708T1 (sl) | 2018-03-01 | 2025-04-30 | Astrazeneca Ab | Farmacevtski sestavki, ki vsebujejo (2S)-{(1S)-1-ciano-2-[4-(3-metil-2-okso-2,3-dihidro-1,3-benzoksazol-5-il)fenil]etil}-1,4-oksazepan-2-karboksamid |
| AU2019306532A1 (en) | 2018-07-17 | 2021-03-04 | Insmed Incorporated | Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides for treating Lupus Nephritis |
| CN109908095A (zh) * | 2019-04-08 | 2019-06-21 | 肇庆学院 | 一种西尼莫德片剂及制备方法 |
| KR20220093330A (ko) | 2019-10-31 | 2022-07-05 | 이도르시아 파마슈티컬스 리미티드 | Cxcr7 안타고니스트와 s1p1 수용체 조절인자의 조합 |
| US11135197B2 (en) | 2020-02-07 | 2021-10-05 | Argentum Pharmaceuticals Llc | Dosage regimen of an S1P receptor modulator |
| WO2024148308A1 (en) | 2023-01-06 | 2024-07-11 | Insmed Incorporated | Novel, reversible dpp1 inhibitors and uses thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104803902A (zh) * | 2008-12-18 | 2015-07-29 | 诺华股份有限公司 | 1-(4-{1-[(e)-4-环己基-3-三氟甲基-苄氧基亚氨基]-乙基}-2-乙基-苄基)-氮杂环丁烷-3-甲酸的半富马酸盐 |
| EP2379069B1 (en) * | 2008-12-22 | 2015-03-04 | Novartis AG | Dosage regimen of an s1p receptor agonist |
| KR101347919B1 (ko) * | 2008-12-22 | 2014-01-07 | 노파르티스 아게 | Ｓ１ｐ 수용체 효능제를 위한 투여 요법 |
| JP2013505983A (ja) * | 2009-09-29 | 2013-02-21 | ノバルティス アーゲー | Ｓ１ｐ受容体モジュレーターの投与計画 |
| PH12013501442B1 (en) * | 2011-01-07 | 2018-04-20 | Novartis Ag | Immunosuppressant formulations |
| WO2012095853A1 (en) | 2011-01-10 | 2012-07-19 | Novartis Pharma Ag | Modified release formulations comprising sip receptor modulators |
| US20150218090A1 (en) * | 2011-10-21 | 2015-08-06 | Novartis Ag | Dosage regimen for an s1p receptor modulator or agonist |
| SG11201607894RA (en) * | 2014-04-10 | 2016-10-28 | Novartis Ag | S1p modulator immediate release dosage regimen |
-
2015
- 2015-04-08 SG SG11201607894RA patent/SG11201607894RA/en unknown
- 2015-04-08 CN CN202310667400.7A patent/CN116650467A/zh active Pending
- 2015-04-08 AU AU2015246036A patent/AU2015246036A1/en not_active Abandoned
- 2015-04-08 JP JP2016561731A patent/JP6674903B2/ja active Active
- 2015-04-08 RU RU2016143979A patent/RU2715734C2/ru not_active Application Discontinuation
- 2015-04-08 KR KR1020167031062A patent/KR20160141841A/ko not_active Ceased
- 2015-04-08 EP EP20215763.2A patent/EP3831378A1/en not_active Withdrawn
- 2015-04-08 EP EP21212400.2A patent/EP4074312A1/en active Pending
- 2015-04-08 CN CN201580031360.0A patent/CN106456552A/zh active Pending
- 2015-04-08 US US15/300,989 patent/US20170027907A1/en not_active Abandoned
- 2015-04-08 RU RU2020107732A patent/RU2020107732A/ru unknown
- 2015-04-08 KR KR1020227039781A patent/KR20220156981A/ko not_active Ceased
- 2015-04-08 TW TW104111330A patent/TW201622721A/zh unknown
- 2015-04-08 IL IL305337A patent/IL305337A/en unknown
- 2015-04-08 WO PCT/IB2015/052550 patent/WO2015155709A1/en not_active Ceased
- 2015-04-08 EP EP15717256.0A patent/EP3129020A1/en not_active Withdrawn
- 2015-04-08 MX MX2016013245A patent/MX2016013245A/es unknown
- 2015-04-08 CA CA2943598A patent/CA2943598C/en active Active
-
2016
- 2016-09-21 ZA ZA2016/06519A patent/ZA201606519B/en unknown
- 2016-09-22 IL IL247986A patent/IL247986A0/en unknown
- 2016-10-04 PH PH12016501965A patent/PH12016501965A1/en unknown
- 2016-10-07 CL CL2016002562A patent/CL2016002562A1/es unknown
-
2018
- 2018-08-21 US US16/106,072 patent/US20190054065A1/en not_active Abandoned
-
2020
- 2020-05-12 AU AU2020203107A patent/AU2020203107B2/en active Active
- 2020-06-02 US US16/890,722 patent/US20220016076A1/en not_active Abandoned
-
2024
- 2024-10-23 US US18/924,230 patent/US20250041266A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015155709A1 (en) | 2015-10-15 |
| AU2015246036A1 (en) | 2016-10-13 |
| JP6674903B2 (ja) | 2020-04-01 |
| KR20220156981A (ko) | 2022-11-28 |
| CA2943598A1 (en) | 2015-10-15 |
| AU2020203107A1 (en) | 2020-05-28 |
| CL2016002562A1 (es) | 2017-07-28 |
| SG11201607894RA (en) | 2016-10-28 |
| CN116650467A (zh) | 2023-08-29 |
| IL247986A0 (en) | 2016-11-30 |
| RU2016143979A (ru) | 2018-05-14 |
| US20220016076A1 (en) | 2022-01-20 |
| RU2020107732A (ru) | 2020-03-30 |
| RU2016143979A3 (enExample) | 2018-11-12 |
| RU2715734C2 (ru) | 2020-03-03 |
| EP3129020A1 (en) | 2017-02-15 |
| PH12016501965A1 (en) | 2017-01-09 |
| ZA201606519B (en) | 2017-11-29 |
| TW201622721A (zh) | 2016-07-01 |
| US20170027907A1 (en) | 2017-02-02 |
| MX2016013245A (es) | 2017-01-16 |
| KR20160141841A (ko) | 2016-12-09 |
| CA2943598C (en) | 2023-03-07 |
| CN106456552A (zh) | 2017-02-22 |
| EP4074312A1 (en) | 2022-10-19 |
| JP2017510607A (ja) | 2017-04-13 |
| US20250041266A1 (en) | 2025-02-06 |
| AU2020203107B2 (en) | 2021-10-21 |
| US20190054065A1 (en) | 2019-02-21 |
| EP3831378A1 (en) | 2021-06-09 |
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