IL299207A - Methods of allergy treatment using anti-BET V 1 antibodies - Google Patents
Methods of allergy treatment using anti-BET V 1 antibodiesInfo
- Publication number
- IL299207A IL299207A IL299207A IL29920722A IL299207A IL 299207 A IL299207 A IL 299207A IL 299207 A IL299207 A IL 299207A IL 29920722 A IL29920722 A IL 29920722A IL 299207 A IL299207 A IL 299207A
- Authority
- IL
- Israel
- Prior art keywords
- seq
- amino acid
- acid sequence
- bet
- subject
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/16—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39575—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from other living beings excluding bacteria and viruses, e.g. protozoa, fungi, plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063047126P | 2020-07-01 | 2020-07-01 | |
| US202063129253P | 2020-12-22 | 2020-12-22 | |
| PCT/US2021/039945 WO2022006305A1 (en) | 2020-07-01 | 2021-06-30 | Methods of treating allergy using anti-bet v 1 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL299207A true IL299207A (en) | 2023-02-01 |
Family
ID=77168400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL299207A IL299207A (en) | 2020-07-01 | 2021-06-30 | Methods of allergy treatment using anti-BET V 1 antibodies |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11897945B2 (enExample) |
| EP (1) | EP4175986A1 (enExample) |
| JP (1) | JP7897809B2 (enExample) |
| KR (1) | KR20230030573A (enExample) |
| CN (1) | CN115698059A (enExample) |
| AU (1) | AU2021300129A1 (enExample) |
| BR (1) | BR112022026279A2 (enExample) |
| CA (1) | CA3177918A1 (enExample) |
| CL (1) | CL2022003744A1 (enExample) |
| IL (1) | IL299207A (enExample) |
| MX (1) | MX2022015677A (enExample) |
| WO (1) | WO2022006305A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL270894B2 (en) * | 2017-06-01 | 2023-04-01 | Regeneron Pharma | Human antibodies to bet v 1 and methods of using them |
| US11897945B2 (en) | 2020-07-01 | 2024-02-13 | Regeneron Pharmaceuticals, Inc. | Methods of treating allergy using anti-Bet v 1 antibodies |
| WO2024251358A1 (en) * | 2023-06-07 | 2024-12-12 | Mabylon Ag | Anti-allergen antibodies and uses thereof |
| WO2026125663A2 (en) * | 2024-12-11 | 2026-06-18 | Mabylon Ag | Anti-allergen antibodies and uses thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5411594A (en) | 1992-10-27 | 1994-05-24 | Biomay Produktions- Und Handelsgesellschaft M.B.H. | Molecule fragments (peptides) of the main allergens contained in the pollen of trees of the (fagales) order |
| WO1994014475A1 (en) | 1992-12-21 | 1994-07-07 | Tanox Biosystems, Inc. | ALLERGEN-SPECIFIC IgA MONOCLONAL ANTIBODIES AND RELATED PRODUCTS FOR ALLERGY TREATMENT |
| EP0619323A1 (en) | 1993-04-09 | 1994-10-12 | Schering-Plough | Human monoclonal antibodies and processes and materials for making such antibodies |
| GB0002386D0 (en) | 2000-02-02 | 2000-03-22 | Novartis Nutrition Ag | Therapeutic composition |
| US6849259B2 (en) | 2000-06-16 | 2005-02-01 | Symphogen A/S | Polyclonal antibody composition for treating allergy |
| US6596541B2 (en) | 2000-10-31 | 2003-07-22 | Regeneron Pharmaceuticals, Inc. | Methods of modifying eukaryotic cells |
| DK1219299T4 (da) | 2000-12-28 | 2011-02-14 | Biomay Ag | Allergivacciner og fremstilling deraf |
| US20040101920A1 (en) | 2002-11-01 | 2004-05-27 | Czeslaw Radziejewski | Modification assisted profiling (MAP) methodology |
| EP1740946B1 (en) | 2004-04-20 | 2013-11-06 | Genmab A/S | Human monoclonal antibodies against cd20 |
| ITMI20052517A1 (it) | 2005-12-29 | 2007-06-30 | Lofarma Spa | Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa |
| AT503297B1 (de) | 2006-05-18 | 2007-09-15 | Biomay Ag | Allergen-spezifische antikörper |
| WO2010089671A2 (en) * | 2009-02-09 | 2010-08-12 | Anergis S.A. | Contiguous overlapping peptides for treatment of birch pollen allergy |
| TWI655207B (zh) | 2013-07-30 | 2019-04-01 | 再生元醫藥公司 | 抗活化素ａ之抗體及其用途 |
| EP3036543B1 (en) | 2013-08-23 | 2019-06-19 | Regeneron Pharmaceuticals, Inc. | Diagnostic tests and methods for assessing safety, efficacy or outcome of allergen-specific immunotherapy (sit) |
| TWI756187B (zh) | 2015-10-09 | 2022-03-01 | 美商再生元醫藥公司 | 抗ｌａｇ３抗體及其用途 |
| IL270894B2 (en) * | 2017-06-01 | 2023-04-01 | Regeneron Pharma | Human antibodies to bet v 1 and methods of using them |
| CN108129558B (zh) * | 2017-12-21 | 2021-10-12 | 中国医学科学院北京协和医院 | 一种桦树花粉主要致敏蛋白Bet v 8的提取和分离纯化方法及应用 |
| TWI838389B (zh) | 2018-07-19 | 2024-04-11 | 美商再生元醫藥公司 | 雙特異性抗-BCMAｘ抗-CD3抗體及其用途 |
| US11897945B2 (en) | 2020-07-01 | 2024-02-13 | Regeneron Pharmaceuticals, Inc. | Methods of treating allergy using anti-Bet v 1 antibodies |
| CN121241065A (zh) * | 2023-03-31 | 2025-12-30 | 爱尔开-阿贝优公司 | 适用于治疗树木花粉过敏的过敏原结合抗体 |
| WO2025165851A1 (en) | 2024-01-30 | 2025-08-07 | Regeneron Pharmaceuticals, Inc. | Methods of treating allergy using anti-bet v 1 antibodies |
-
2021
- 2021-06-30 US US17/364,299 patent/US11897945B2/en active Active
- 2021-06-30 AU AU2021300129A patent/AU2021300129A1/en active Pending
- 2021-06-30 KR KR1020227043651A patent/KR20230030573A/ko active Pending
- 2021-06-30 MX MX2022015677A patent/MX2022015677A/es unknown
- 2021-06-30 JP JP2022579724A patent/JP7897809B2/ja active Active
- 2021-06-30 WO PCT/US2021/039945 patent/WO2022006305A1/en not_active Ceased
- 2021-06-30 IL IL299207A patent/IL299207A/en unknown
- 2021-06-30 CN CN202180043390.9A patent/CN115698059A/zh active Pending
- 2021-06-30 CA CA3177918A patent/CA3177918A1/en active Pending
- 2021-06-30 EP EP21749400.4A patent/EP4175986A1/en active Pending
- 2021-06-30 BR BR112022026279A patent/BR112022026279A2/pt unknown
-
2022
- 2022-12-23 CL CL2022003744A patent/CL2022003744A1/es unknown
-
2023
- 2023-12-19 US US18/545,795 patent/US12583914B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US12583914B2 (en) | 2026-03-24 |
| WO2022006305A1 (en) | 2022-01-06 |
| KR20230030573A (ko) | 2023-03-06 |
| CL2022003744A1 (es) | 2023-06-02 |
| JP7897809B2 (ja) | 2026-07-30 |
| US11897945B2 (en) | 2024-02-13 |
| JP2023531968A (ja) | 2023-07-26 |
| BR112022026279A2 (pt) | 2023-02-14 |
| MX2022015677A (es) | 2023-02-22 |
| EP4175986A1 (en) | 2023-05-10 |
| US20240209074A1 (en) | 2024-06-27 |
| CA3177918A1 (en) | 2022-01-06 |
| CN115698059A (zh) | 2023-02-03 |
| AU2021300129A1 (en) | 2022-12-08 |
| US20220002394A1 (en) | 2022-01-06 |
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