IL294443A - Lincrna-deficient non-human animals - Google Patents
Lincrna-deficient non-human animalsInfo
- Publication number
- IL294443A IL294443A IL294443A IL29444322A IL294443A IL 294443 A IL294443 A IL 294443A IL 294443 A IL294443 A IL 294443A IL 29444322 A IL29444322 A IL 29444322A IL 294443 A IL294443 A IL 294443A
- Authority
- IL
- Israel
- Prior art keywords
- cell
- expression
- incrna
- lincrna
- promoter
- Prior art date
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| WO2012018881A2 (en) | 2010-08-03 | 2012-02-09 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for the regulation of rna |
| WO2013134558A1 (en) | 2012-03-07 | 2013-09-12 | The Texas A & M University System | Cancer treatment targeting non-coding rna overexpression |
| JP6475172B2 (ja) | 2013-02-20 | 2019-02-27 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | ラットの遺伝子組換え |
| EP3456831B1 (en) | 2013-04-16 | 2021-07-14 | Regeneron Pharmaceuticals, Inc. | Targeted modification of rat genome |
| BR112017019620A2 (pt) * | 2015-03-16 | 2018-05-15 | Regeneron Pharmaceuticals, Inc. | ?roedor geneticamente modificado, célula ou tecido, métodos para produção de um roedor geneticamente modificado e de uma população de neurônios motores, métodos para seleção de um agente candidato para modular a disfunção neuronal motora e de um agente candidato para redução do estresse oxidativo em um neurônio motor, ácido nucleico, e, célula de roedor? |
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