IL28852A - Preparation 2 - Arylamino - 1, 3 - Diazaciclo alkanes (2) - Google Patents
Preparation 2 - Arylamino - 1, 3 - Diazaciclo alkanes (2)Info
- Publication number
- IL28852A IL28852A IL6728852A IL2885267A IL28852A IL 28852 A IL28852 A IL 28852A IL 6728852 A IL6728852 A IL 6728852A IL 2885267 A IL2885267 A IL 2885267A IL 28852 A IL28852 A IL 28852A
- Authority
- IL
- Israel
- Prior art keywords
- group
- formula
- compound
- general formula
- filtered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
- C07D239/12—Nitrogen atoms not forming part of a nitro radical
- C07D239/14—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE1966B0089635 DE1670162C3 (de) | 1966-10-31 | 1966-10-31 | Verfahren zur Herstellung von 2-substituierten Phenylamino-13-diazacycloalkenen-(2) und dessen Säureadditionssalzen |
DEB0094681 | 1967-09-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL28852A true IL28852A (en) | 1971-11-29 |
Family
ID=25968163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL6728852A IL28852A (en) | 1966-10-31 | 1967-10-30 | Preparation 2 - Arylamino - 1, 3 - Diazaciclo alkanes (2) |
Country Status (13)
Country | Link |
---|---|
US (1) | US3468887A (xx) |
BE (1) | BE705944A (xx) |
CH (1) | CH500987A (xx) |
DE (1) | DE1670274A1 (xx) |
DK (1) | DK124404B (xx) |
ES (1) | ES346635A1 (xx) |
FR (1) | FR7534M (xx) |
GB (1) | GB1180766A (xx) |
IL (1) | IL28852A (xx) |
NL (1) | NL6714808A (xx) |
PL (1) | PL69783B1 (xx) |
SE (1) | SE320375B (xx) |
YU (1) | YU32177B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4036972A (en) * | 1973-02-23 | 1977-07-19 | Boehringer Ingelheim Gmbh | 2-(N-thienylmethyl-phenylamino)-imidazolines-(2) and salts thereof |
US3931152A (en) * | 1974-01-29 | 1976-01-06 | American Cyanamid Company | 2-(1,3-Diazacycloalkenyl)-2-hydrazones of substituted chalcones |
US4125620A (en) | 1974-10-01 | 1978-11-14 | Boehringer Ingelheim Gmbh | 2-[(2',6'-Disubstituted-phenyl)-imino]-imidazolidines and salts thereof |
NL7711390A (nl) * | 1977-10-18 | 1979-04-20 | Philips Nv | Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen. |
MTP837B (en) * | 1977-11-07 | 1979-10-22 | Hoffman La Roche And Co Aktien | Derivatives 2 finino-imidazolidire |
DE2806775A1 (de) * | 1978-02-17 | 1979-08-30 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
DE2806811A1 (de) * | 1978-02-17 | 1979-08-23 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylimino- imidazolidine, deren saeureadditionssalze, diese enthaltene arzneimittel und verfahren zur herstellung derselben |
DE3168754D1 (en) * | 1980-07-09 | 1985-03-21 | Beecham Group Plc | Clonidine derivatives useful in the treatment of diarrhoea |
US4644007A (en) * | 1981-11-20 | 1987-02-17 | Alcon Laboratories, Inc. | 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods |
US4515800A (en) * | 1981-11-20 | 1985-05-07 | Icilio Cavero | Method of lowering intraocular pressure using phenylimino-imidazoles |
US4517199A (en) * | 1981-11-20 | 1985-05-14 | Alcon Laboratories, Inc. | Method for lowering intraocular pressure using phenylimino-imidazoles |
CA1201066A (en) * | 1981-11-20 | 1986-02-25 | Alcon Laboratories, Inc. | N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure |
US4461904A (en) * | 1981-11-20 | 1984-07-24 | Alcon Laboratories, Inc. | 2-(Trisubstituted phenylimino)-imidazolines |
US4587257A (en) * | 1984-12-14 | 1986-05-06 | Alcon Laboratories, Inc. | Control of ocular bleeding using clonidine derivatives |
US5212196A (en) * | 1986-10-21 | 1993-05-18 | Alcon Laboratories, Inc. | Control of post-surgical intraocular pressure using clonidine derivatives |
CA1334168C (en) * | 1988-04-26 | 1995-01-31 | Louis M. De Santis | Antiglaucoma compositions containing combinations of .alpha.-2 agonists and .beta. blockers |
GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
DE69311361T2 (de) * | 1992-10-13 | 1998-01-08 | Alcon Lab Inc | Zusammensetzungen zur behandlung von glaukoma die prostaglandine und clonidinderivate enthalten |
US5523316A (en) * | 1994-06-23 | 1996-06-04 | Alcon Laboratories, Inc. | Intraocular irrigating solution containing agent for controlling IOP |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA625631A (en) * | 1961-08-15 | Chas. Pfizer And Co. | Derivatives of diazacycloalkenes | |
US3147275A (en) * | 1964-09-01 | Nh-cha | ||
US2899426A (en) * | 1959-08-11 | Synthesis of l | ||
US2899434A (en) * | 1959-08-11 | Z-phenylamino-l | ||
US3190802A (en) * | 1961-10-09 | 1965-06-22 | Boehringer Sohn Ingelheim | Shaving composition and method of using same |
US3236857A (en) * | 1961-10-09 | 1966-02-22 | Boehringer Sohn Ingelheim | 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products |
-
1967
- 1967-09-27 DE DE19671670274 patent/DE1670274A1/de active Pending
- 1967-10-24 US US677755A patent/US3468887A/en not_active Expired - Lifetime
- 1967-10-30 IL IL6728852A patent/IL28852A/en unknown
- 1967-10-30 DK DK540067AA patent/DK124404B/da not_active IP Right Cessation
- 1967-10-30 PL PL67123313A patent/PL69783B1/pl unknown
- 1967-10-30 CH CH1517267A patent/CH500987A/de not_active IP Right Cessation
- 1967-10-31 NL NL6714808A patent/NL6714808A/xx unknown
- 1967-10-31 ES ES346635A patent/ES346635A1/es not_active Expired
- 1967-10-31 SE SE14913/67A patent/SE320375B/xx unknown
- 1967-10-31 GB GB49436/67A patent/GB1180766A/en not_active Expired
- 1967-10-31 BE BE705944A patent/BE705944A/xx not_active IP Right Cessation
- 1967-11-02 YU YU2134/67A patent/YU32177B/xx unknown
-
1968
- 1968-01-31 FR FR138179A patent/FR7534M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR7534M (xx) | 1969-12-22 |
BE705944A (xx) | 1968-04-30 |
CH500987A (de) | 1970-12-31 |
US3468887A (en) | 1969-09-23 |
PL69783B1 (xx) | 1973-08-31 |
ES346635A1 (es) | 1969-05-16 |
DK124404B (da) | 1972-10-16 |
YU213467A (en) | 1973-12-31 |
DE1670274A1 (de) | 1970-07-16 |
YU32177B (en) | 1974-06-30 |
GB1180766A (en) | 1970-02-11 |
SE320375B (xx) | 1970-02-09 |
NL6714808A (xx) | 1968-05-01 |
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