IL28427A - 3,1-Benzaoxazine-2 helices and a process for their preparation - Google Patents

3,1-Benzaoxazine-2 helices and a process for their preparation

Info

Publication number
IL28427A
IL28427A IL28427A IL2842767A IL28427A IL 28427 A IL28427 A IL 28427A IL 28427 A IL28427 A IL 28427A IL 2842767 A IL2842767 A IL 2842767A IL 28427 A IL28427 A IL 28427A
Authority
IL
Israel
Prior art keywords
benzoxazin
dimethyl
group
carbon atoms
hydrogen
Prior art date
Application number
IL28427A
Other languages
English (en)
Hebrew (he)
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of IL28427A publication Critical patent/IL28427A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL28427A 1966-08-03 1967-07-31 3,1-Benzaoxazine-2 helices and a process for their preparation IL28427A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1800566 1966-08-03
IT2105166 1966-08-03
IT1516667 1967-04-20

Publications (1)

Publication Number Publication Date
IL28427A true IL28427A (en) 1971-04-28

Family

ID=27272868

Family Applications (1)

Application Number Title Priority Date Filing Date
IL28427A IL28427A (en) 1966-08-03 1967-07-31 3,1-Benzaoxazine-2 helices and a process for their preparation

Country Status (13)

Country Link
US (1) US3526621A (fr)
BE (2) BE702201A (fr)
CH (1) CH478828A (fr)
DE (2) DE1695756C3 (fr)
DK (2) DK118877B (fr)
ES (2) ES343737A1 (fr)
FR (2) FR6494M (fr)
GB (1) GB1135899A (fr)
IL (1) IL28427A (fr)
NL (2) NL6710332A (fr)
NO (2) NO121275B (fr)
SE (2) SE331997B (fr)
YU (2) YU31634B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301283A (en) * 1979-09-27 1981-11-17 Sterling Drug Inc. Process for preparing 2-oxo-dihydrobenzo(d)(1,3)-oxazines
DE3026534A1 (de) * 1980-07-12 1982-03-18 C.H. Boehringer Sohn, 6507 Ingelheim 3,1-benzoxazin-2-one, ihre herstellung und verwendung
DE3217012A1 (de) * 1982-05-06 1983-11-10 Dr. Karl Thomae Gmbh, 7950 Biberach Benzoxazin-2-one, deren herstellung und diese verbindungen enthaltende arzneimittel
IL106507A (en) * 1992-08-07 1997-11-20 Merck & Co Inc Pharmaceutical compositions containing benzoxazinones and some novel compounds of this type
US5519021A (en) * 1992-08-07 1996-05-21 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
WO1995020389A1 (fr) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones en tant qu'inhibiteurs de transcriptase inverse du vih
US5874430A (en) * 1996-10-02 1999-02-23 Dupont Pharmaceuticals Company 4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same
EP1359147A1 (fr) * 1996-10-02 2003-11-05 Bristol-Myers Squibb Pharma Company 4,4-disubstitue-1,4-dihydro-2h-3,1-benzoxazine-2-ones utiles en tant qu'inhibiteurs de transcriptase inverse du VIH, intermediaires et procedes de fabrication correspondants
US5932726A (en) * 1996-12-16 1999-08-03 Dupont Pharmaceuticals Company Asymmetric synthesis of benzoxazinones
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6509334B1 (en) * 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
UA73119C2 (en) * 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
EP1756072A2 (fr) 2004-04-27 2007-02-28 Wyeth Purification de modulateurs de recepteur de progesterone

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3047573A (en) * 1962-07-31 N-alkylamido substituted
US2940971A (en) * 1960-06-14 Tetrahydrooxazenones
US1951807A (en) * 1931-04-17 1934-03-20 Holimann La Roche Inc 4-phenalkyl-3-keto-3.4-dihydro-1.4-benzoxazines and process for the manufacture of same
US2947745A (en) * 1958-08-11 1960-08-02 Smith Kline French Lab Substituted phenoxazine sedative agents
US3280120A (en) * 1964-03-09 1966-10-18 Rexall Drug Chemical Substituted benzoxazines, process therefor and intermediates

Also Published As

Publication number Publication date
DE1695756B2 (de) 1978-02-09
BE702201A (fr) 1968-02-02
NO121275B (fr) 1971-02-08
DE1695756A1 (de) 1972-03-02
DE1695780B2 (de) 1978-12-21
YU190067A (en) 1973-02-28
YU152667A (en) 1973-02-28
CH478828A (de) 1969-09-30
US3526621A (en) 1970-09-01
NL6710332A (fr) 1968-02-05
BE704583A (fr) 1968-04-02
NL6713047A (fr) 1968-10-21
SE337823B (fr) 1971-08-23
FR6494M (fr) 1968-11-25
ES343737A1 (es) 1968-10-16
DK111568B (da) 1968-09-16
DE1695780A1 (de) 1971-04-29
FR93909E (fr) 1969-06-06
DE1695780C3 (de) 1979-08-23
YU31636B (en) 1973-10-31
DK118877B (da) 1970-10-19
GB1135899A (en) 1968-12-04
DE1695756C3 (de) 1978-10-05
NO121045B (fr) 1971-01-11
ES345647A2 (es) 1968-11-16
YU31634B (en) 1973-10-31
SE331997B (fr) 1971-01-25

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