IL283998A - NK cells are derived from a mononuclear cell and methods - Google Patents

NK cells are derived from a mononuclear cell and methods

Info

Publication number
IL283998A
IL283998A IL283998A IL28399821A IL283998A IL 283998 A IL283998 A IL 283998A IL 283998 A IL283998 A IL 283998A IL 28399821 A IL28399821 A IL 28399821A IL 283998 A IL283998 A IL 283998A
Authority
IL
Israel
Prior art keywords
cells
methods
cell derived
mononuclear cell
mononuclear
Prior art date
Application number
IL283998A
Other languages
English (en)
Hebrew (he)
Original Assignee
Nantkwest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nantkwest Inc filed Critical Nantkwest Inc
Publication of IL283998A publication Critical patent/IL283998A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2315—Interleukin-15 (IL-15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/515—CD3, T-cell receptor complex
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
IL283998A 2019-07-08 2021-06-14 NK cells are derived from a mononuclear cell and methods IL283998A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/040867 WO2021006875A1 (en) 2019-07-08 2019-07-08 Mononuclear cell derived nk cells

Publications (1)

Publication Number Publication Date
IL283998A true IL283998A (en) 2021-07-29

Family

ID=74114919

Family Applications (1)

Application Number Title Priority Date Filing Date
IL283998A IL283998A (en) 2019-07-08 2021-06-14 NK cells are derived from a mononuclear cell and methods

Country Status (9)

Country Link
EP (1) EP3853354A4 (ja)
JP (2) JP7213976B2 (ja)
KR (1) KR20210080566A (ja)
CN (1) CN113166726A (ja)
AU (1) AU2019456283B2 (ja)
CA (1) CA3120695A1 (ja)
IL (1) IL283998A (ja)
SG (1) SG11202104339WA (ja)
WO (1) WO2021006875A1 (ja)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2411507T (pt) * 2009-03-26 2020-01-09 Cellprotect Nordic Pharmaceuticals Ab Expansão de células nk
CA2781969A1 (en) 2009-12-04 2011-06-09 Stem Cell & Regenerative Medicine International, Inc. Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
EP2539442A1 (en) 2010-02-24 2013-01-02 Ingo Schmidt-Wolf Method for the generation of a cik cell and nk cell population
KR102070098B1 (ko) 2010-09-21 2020-01-28 알토 바이오사이언스 코포레이션 다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법
EP2666466A4 (en) * 2011-01-21 2014-11-05 Biotherapy Inst Of Japan PROCESS FOR THE PRODUCTION OF BLOOD PREPARATION ENRICHED IN NK CELLS
ES2856825T3 (es) 2011-03-18 2021-09-28 Glycostem Therapeutics B V Generación de células NK y progenitores de células NK
ES2771248T3 (es) 2012-02-08 2020-07-06 Glycostem Therapeutics B V Diferenciación de células NK ex vivo de células hematopoyéticas CD34+
CN102988415B (zh) 2012-08-15 2014-11-19 中航（宁夏）生物有限责任公司 人异基因有核细胞工业化制备自然杀伤性细胞(nk)及注射液
WO2015154012A1 (en) * 2014-04-03 2015-10-08 Memorial Sloan-Kettering Cancer Center Clonogenic natural killer (nk) cell populations and methods of producing and using such populations
US11773364B2 (en) 2014-04-28 2023-10-03 Vivabiocell S.P.A. Automated cell culturing and harvesting device
KR101683614B1 (ko) * 2016-02-15 2016-12-07 신동혁 Nk세포배양용 배지첨가키트 및 상기 키트를 이용한 nk세포배양방법
EP3515471A4 (en) * 2016-09-23 2020-07-01 The Regents of The University of California SELF-MODIFIED LENTIVIRAL-MODIFIED IRRADIATED WHOLE CELL ANTI-TUMOR VACCINES TO EXPRESS CD80, IL-15 AND THE IL-15 ALPHA RECEPTOR
AU2017342560B2 (en) 2016-10-14 2022-03-17 Xencor, Inc. IL15/IL15Ralpha heterodimeric Fc-fusion proteins
EA201991632A1 (ru) * 2017-02-28 2020-03-12 Аффимед Гмбх Комбинация антитела против cd16a с цитокином
US11129883B2 (en) 2017-03-06 2021-09-28 Altor BioScience, LLC. IL-15-based fusions to IL-12 and IL-18
KR20200015469A (ko) * 2017-05-11 2020-02-12 난트케이웨스트, 인크. 항-egfr/고친화성 nk-세포 조성물 및 척색종 치료 방법
WO2018213828A1 (en) * 2017-05-19 2018-11-22 Case Western Reserve University Compositions and methods for expanding ex vivo natural killer cells and therapeutic uses thereof
CN108070556A (zh) * 2017-07-26 2018-05-25 深圳市北科生物科技有限公司 用于免疫细胞培养的方法和组合物
CN111655716B (zh) * 2017-08-28 2024-03-08 艾尔特生物科技公司 基于il-15的与il-7和il-21的融合体

Also Published As

Publication number Publication date
CN113166726A (zh) 2021-07-23
EP3853354A1 (en) 2021-07-28
JP2023040184A (ja) 2023-03-22
AU2019456283B2 (en) 2023-06-08
CA3120695A1 (en) 2021-01-14
AU2019456283A1 (en) 2021-05-20
EP3853354A4 (en) 2022-04-20
KR20210080566A (ko) 2021-06-30
WO2021006875A1 (en) 2021-01-14
JP2022513614A (ja) 2022-02-09
SG11202104339WA (en) 2021-05-28
JP7213976B2 (ja) 2023-01-27

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