EP3853354A4 - NK CELLS DERIVED FROM MONONUCLEAR CELLS - Google Patents
NK CELLS DERIVED FROM MONONUCLEAR CELLS Download PDFInfo
- Publication number
- EP3853354A4 EP3853354A4 EP19936966.1A EP19936966A EP3853354A4 EP 3853354 A4 EP3853354 A4 EP 3853354A4 EP 19936966 A EP19936966 A EP 19936966A EP 3853354 A4 EP3853354 A4 EP 3853354A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- cells
- cell derived
- mononuclear cell
- mononuclear
- derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000005087 mononuclear cell Anatomy 0.000 title 1
- 210000000822 natural killer cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2315—Interleukin-15 (IL-15)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/515—CD3, T-cell receptor complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2019/040867 WO2021006875A1 (en) | 2019-07-08 | 2019-07-08 | Mononuclear cell derived nk cells |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3853354A1 EP3853354A1 (en) | 2021-07-28 |
EP3853354A4 true EP3853354A4 (en) | 2022-04-20 |
Family
ID=74114919
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19936966.1A Pending EP3853354A4 (en) | 2019-07-08 | 2019-07-08 | NK CELLS DERIVED FROM MONONUCLEAR CELLS |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP3853354A4 (ja) |
JP (2) | JP7213976B2 (ja) |
KR (1) | KR20210080566A (ja) |
CN (1) | CN113166726A (ja) |
AU (1) | AU2019456283B2 (ja) |
CA (1) | CA3120695A1 (ja) |
IL (1) | IL283998A (ja) |
SG (1) | SG11202104339WA (ja) |
WO (1) | WO2021006875A1 (ja) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180355317A1 (en) * | 2016-02-15 | 2018-12-13 | Dong Hyuk Shin | Method of culturing nk cells and kits containing medium addtions therefore |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102428173B (zh) * | 2009-03-26 | 2014-07-30 | 细胞维护北欧制药公司 | Nk细胞的扩增 |
RU2012127811A (ru) | 2009-12-04 | 2014-01-10 | Стем Селл Энд Ридженерэйтив Медсин Интернэшнл, Инк. | Способ получения клеток-натуральных киллеров и дендритных клеток из человеческих эмбриональных гемангиобластов, полученных из стволовых клеток |
AU2010347018A1 (en) | 2010-02-24 | 2012-09-20 | Ingo Schmidt-Wolf | Method for the generation of a CIK cell and NK cell population |
DK3327040T3 (da) | 2010-09-21 | 2021-09-20 | Altor Bioscience Corp | Multimeriske opløselige il-15-fusionsmolekyler og fremgangsmåder til at fremstille og anvende samme |
US20130295671A1 (en) | 2011-01-21 | 2013-11-07 | Biotherapy Institute Of Japan | Method for producing nk cell-enriched blood preparation |
WO2012128622A1 (en) | 2011-03-18 | 2012-09-27 | Ipd-Therapeutics B.V. | Generation of nk cells and nk-cell progenitors |
PL2812011T3 (pl) | 2012-02-08 | 2020-06-29 | Glycostem Therapeutics B.V. | Różnicowanie komórek NK z komórek hematopoetycznych CD34<sup>+</sup> ex vivo |
CN102988415B (zh) | 2012-08-15 | 2014-11-19 | 中航(宁夏)生物有限责任公司 | 人异基因有核细胞工业化制备自然杀伤性细胞(nk)及注射液 |
US11773364B2 (en) | 2014-04-28 | 2023-10-03 | Vivabiocell S.P.A. | Automated cell culturing and harvesting device |
EP3515471A4 (en) * | 2016-09-23 | 2020-07-01 | The Regents of The University of California | SELF-MODIFIED LENTIVIRAL-MODIFIED IRRADIATED WHOLE CELL ANTI-TUMOR VACCINES TO EXPRESS CD80, IL-15 AND THE IL-15 ALPHA RECEPTOR |
WO2018071919A1 (en) | 2016-10-14 | 2018-04-19 | Xencor, Inc. | IL15/IL15Rα HETERODIMERIC FC-FUSION PROTEINS |
EP3589316A1 (en) * | 2017-02-28 | 2020-01-08 | Affimed GmbH | Combination of an anti-cd16a antibody with a cytokine |
CN110785435B (zh) | 2017-03-06 | 2024-01-23 | 艾尔特生物科技公司 | 与il-12和il-18的基于il-15的融合物 |
WO2018209208A1 (en) * | 2017-05-11 | 2018-11-15 | Nantkwest, Inc. | Anti-egfr/high affinity nk-cells compositions and methods for chordoma treatment |
-
2019
- 2019-07-08 AU AU2019456283A patent/AU2019456283B2/en active Active
- 2019-07-08 EP EP19936966.1A patent/EP3853354A4/en active Pending
- 2019-07-08 CA CA3120695A patent/CA3120695A1/en active Pending
- 2019-07-08 CN CN201980078702.2A patent/CN113166726A/zh active Pending
- 2019-07-08 SG SG11202104339WA patent/SG11202104339WA/en unknown
- 2019-07-08 KR KR1020217018216A patent/KR20210080566A/ko not_active Application Discontinuation
- 2019-07-08 JP JP2021527968A patent/JP7213976B2/ja active Active
- 2019-07-08 WO PCT/US2019/040867 patent/WO2021006875A1/en unknown
-
2021
- 2021-06-14 IL IL283998A patent/IL283998A/en unknown
-
2023
- 2023-01-10 JP JP2023001780A patent/JP2023040184A/ja active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20180355317A1 (en) * | 2016-02-15 | 2018-12-13 | Dong Hyuk Shin | Method of culturing nk cells and kits containing medium addtions therefore |
Non-Patent Citations (1)
Title |
---|
HONG-RAE LEE ET AL: "Expansion of cytotoxic natural killer cells using irradiated autologous peripheral blood mononuclear cells and anti-CD16 antibody", SCIENTIFIC REPORTS, vol. 7, no. 1, 11 September 2017 (2017-09-11), XP055762396, DOI: 10.1038/s41598-017-09259-1 * |
Also Published As
Publication number | Publication date |
---|---|
EP3853354A1 (en) | 2021-07-28 |
AU2019456283B2 (en) | 2023-06-08 |
WO2021006875A1 (en) | 2021-01-14 |
JP2023040184A (ja) | 2023-03-22 |
KR20210080566A (ko) | 2021-06-30 |
JP2022513614A (ja) | 2022-02-09 |
SG11202104339WA (en) | 2021-05-28 |
AU2019456283A1 (en) | 2021-05-20 |
CA3120695A1 (en) | 2021-01-14 |
JP7213976B2 (ja) | 2023-01-27 |
CN113166726A (zh) | 2021-07-23 |
IL283998A (en) | 2021-07-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20210421 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
RAP3 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: IMMUNITYBIO, INC. |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20220322 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 5/0783 20100101AFI20220316BHEP |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) |