SG11202104339WA - Mononuclear cell derived nk cells - Google Patents

Mononuclear cell derived nk cells

Info

Publication number
SG11202104339WA
SG11202104339WA SG11202104339WA SG11202104339WA SG11202104339WA SG 11202104339W A SG11202104339W A SG 11202104339WA SG 11202104339W A SG11202104339W A SG 11202104339WA SG 11202104339W A SG11202104339W A SG 11202104339WA SG 11202104339W A SG11202104339W A SG 11202104339WA
Authority
SG
Singapore
Prior art keywords
cells
cell derived
mononuclear cell
mononuclear
derived
Prior art date
Application number
SG11202104339WA
Other languages
English (en)
Inventor
Rohit Duggal
Ranjeet Sinha
Wenzhao Li
Jason Isaacson
Karl Marquez
Patrick Soon-Shiong
Original Assignee
Nantkwest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nantkwest Inc filed Critical Nantkwest Inc
Publication of SG11202104339WA publication Critical patent/SG11202104339WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0646Natural killers cells [NK], NKT cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/2315Interleukin-15 (IL-15)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/515CD3, T-cell receptor complex
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/599Cell markers; Cell surface determinants with CD designations not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG11202104339WA 2019-07-08 2019-07-08 Mononuclear cell derived nk cells SG11202104339WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/040867 WO2021006875A1 (en) 2019-07-08 2019-07-08 Mononuclear cell derived nk cells

Publications (1)

Publication Number Publication Date
SG11202104339WA true SG11202104339WA (en) 2021-05-28

Family

ID=74114919

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104339WA SG11202104339WA (en) 2019-07-08 2019-07-08 Mononuclear cell derived nk cells

Country Status (9)

Country Link
EP (1) EP3853354A4 (ja)
JP (2) JP7213976B2 (ja)
KR (1) KR20210080566A (ja)
CN (1) CN113166726A (ja)
AU (1) AU2019456283B2 (ja)
CA (1) CA3120695A1 (ja)
IL (1) IL283998A (ja)
SG (1) SG11202104339WA (ja)
WO (1) WO2021006875A1 (ja)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101881520B1 (ko) * 2009-03-26 2018-07-24 셀프로텍트 노딕 파머수티컬스 에이비 Nk 세포의 증식
CA2781969A1 (en) 2009-12-04 2011-06-09 Stem Cell & Regenerative Medicine International, Inc. Method of generating natural killer cells and dendritic cells from human embryonic stem cell-derived hemangioblasts
US20130059379A1 (en) 2010-02-24 2013-03-07 Ingo Schmidt-Wolf Method for the generation of a cik cell and nk cell population
ES2651170T3 (es) 2010-09-21 2018-01-24 Altor Bioscience Corporation Moléculas de fusión solubles multímeras de IL-15 y métodos para elaborar y usar las mismas
EP2666466A4 (en) * 2011-01-21 2014-11-05 Biotherapy Inst Of Japan PROCESS FOR THE PRODUCTION OF BLOOD PREPARATION ENRICHED IN NK CELLS
US11118165B2 (en) 2011-03-18 2021-09-14 Glycostem Therapeutics B.V. Generation of NK cells and NK-cell progenitors
WO2013119118A1 (en) 2012-02-08 2013-08-15 Ipd-Therapeutics B.V. Ex vivo nk cell differentiation from cd34+ hematopoietic cells
CN102988415B (zh) 2012-08-15 2014-11-19 中航(宁夏)生物有限责任公司 人异基因有核细胞工业化制备自然杀伤性细胞(nk)及注射液
CN106232801A (zh) 2014-04-28 2016-12-14 维瓦生物细胞股份公司 自动化细胞培养和收获装置
KR101683614B1 (ko) 2016-02-15 2016-12-07 신동혁 Nk세포배양용 배지첨가키트 및 상기 키트를 이용한 nk세포배양방법
WO2018058067A1 (en) * 2016-09-23 2018-03-29 The Regents Of The University Of California Autologous irradiated whole cell tumor vaccines lentivirally engineered to express cd80, il-15 and il-15 receptor alpha
AU2017342559B2 (en) 2016-10-14 2022-03-24 Xencor, Inc. Bispecific heterodimeric fusion proteins containing IL-15/IL-15Ralpha Fc-fusion proteins and PD-1 antibody fragments
JP2020510657A (ja) * 2017-02-28 2020-04-09 アッフィメッド・ゲー・エム・ベー・ハーAffimed Gmbh 抗cd16a抗体のサイトカインとの組み合わせ
CA3216726A1 (en) 2017-03-06 2018-09-13 Altor Bioscience Corporation Il-15-based fusions to il-12 and il-18
AU2018265534A1 (en) * 2017-05-11 2019-10-31 Nantkwest, Inc. Anti-EGFR/high affinity NK-cells compositions and methods for chordoma treatment

Also Published As

Publication number Publication date
KR20210080566A (ko) 2021-06-30
AU2019456283A1 (en) 2021-05-20
EP3853354A4 (en) 2022-04-20
CA3120695A1 (en) 2021-01-14
JP7213976B2 (ja) 2023-01-27
IL283998A (en) 2021-07-29
AU2019456283B2 (en) 2023-06-08
CN113166726A (zh) 2021-07-23
EP3853354A1 (en) 2021-07-28
JP2023040184A (ja) 2023-03-22
JP2022513614A (ja) 2022-02-09
WO2021006875A1 (en) 2021-01-14

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