IL28098A - Stable reagent mixtures containing polyhydric compounds - Google Patents
Stable reagent mixtures containing polyhydric compoundsInfo
- Publication number
- IL28098A IL28098A IL28098A IL2809867A IL28098A IL 28098 A IL28098 A IL 28098A IL 28098 A IL28098 A IL 28098A IL 2809867 A IL2809867 A IL 2809867A IL 28098 A IL28098 A IL 28098A
- Authority
- IL
- Israel
- Prior art keywords
- dry
- specimen
- reagent
- enzyme
- substance
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title claims 25
- 239000000203 mixture Substances 0.000 title claims 9
- 150000001875 compounds Chemical class 0.000 title 1
- 238000003556 assay Methods 0.000 claims 12
- 239000007788 liquid Substances 0.000 claims 12
- 239000000126 substance Substances 0.000 claims 12
- 239000007787 solid Substances 0.000 claims 10
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 8
- 102000004190 Enzymes Human genes 0.000 claims 8
- 108090000790 Enzymes Proteins 0.000 claims 8
- 229930195725 Mannitol Natural products 0.000 claims 8
- 239000005515 coenzyme Substances 0.000 claims 8
- 239000000594 mannitol Substances 0.000 claims 8
- 235000010355 mannitol Nutrition 0.000 claims 8
- 230000003287 optical effect Effects 0.000 claims 8
- 239000000872 buffer Substances 0.000 claims 7
- 239000000463 material Substances 0.000 claims 7
- 239000003381 stabilizer Substances 0.000 claims 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 7
- 239000004067 bulking agent Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 239000000758 substrate Substances 0.000 claims 6
- 102000013460 Malate Dehydrogenase Human genes 0.000 claims 5
- 108010026217 Malate Dehydrogenase Proteins 0.000 claims 5
- 239000000243 solution Substances 0.000 claims 5
- 102000003855 L-lactate dehydrogenase Human genes 0.000 claims 4
- 108700023483 L-lactate dehydrogenases Proteins 0.000 claims 4
- DAEPDZWVDSPTHF-UHFFFAOYSA-M sodium pyruvate Chemical compound [Na+].CC(=O)C([O-])=O DAEPDZWVDSPTHF-UHFFFAOYSA-M 0.000 claims 4
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 3
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 3
- 229910019142 PO4 Inorganic materials 0.000 claims 3
- 229960001484 edetic acid Drugs 0.000 claims 3
- 239000008103 glucose Substances 0.000 claims 3
- 239000008101 lactose Substances 0.000 claims 3
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 claims 3
- 235000021317 phosphate Nutrition 0.000 claims 3
- 239000000600 sorbitol Substances 0.000 claims 3
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical compound OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 claims 2
- 102100031126 6-phosphogluconolactonase Human genes 0.000 claims 2
- 108010029731 6-phosphogluconolactonase Proteins 0.000 claims 2
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 claims 2
- 241000220479 Acacia Species 0.000 claims 2
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 claims 2
- 108010018962 Glucosephosphate Dehydrogenase Proteins 0.000 claims 2
- 102000005548 Hexokinase Human genes 0.000 claims 2
- 108700040460 Hexokinases Proteins 0.000 claims 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 2
- 235000010643 Leucaena leucocephala Nutrition 0.000 claims 2
- HDVCHBLHEICPPP-UHFFFAOYSA-N O=P(=O)C1=CC=NC(P(=O)=O)=C1P(=O)=O Chemical class O=P(=O)C1=CC=NC(P(=O)=O)=C1P(=O)=O HDVCHBLHEICPPP-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 2
- 102000003929 Transaminases Human genes 0.000 claims 2
- 108090000340 Transaminases Proteins 0.000 claims 2
- 229910052783 alkali metal Inorganic materials 0.000 claims 2
- -1 alkali metal salts Chemical class 0.000 claims 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims 2
- 235000011130 ammonium sulphate Nutrition 0.000 claims 2
- 235000003704 aspartic acid Nutrition 0.000 claims 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims 2
- 230000002255 enzymatic effect Effects 0.000 claims 2
- 229930195712 glutamate Natural products 0.000 claims 2
- GKQWYZBANWAFMQ-UHFFFAOYSA-M lithium;2-hydroxypropanoate Chemical compound [Li+].CC(O)C([O-])=O GKQWYZBANWAFMQ-UHFFFAOYSA-M 0.000 claims 2
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 229940054269 sodium pyruvate Drugs 0.000 claims 2
- 230000000087 stabilizing effect Effects 0.000 claims 2
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 claims 1
- ACFIXJIJDZMPPO-NNYOXOHSSA-N NADPH Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](OP(O)(O)=O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 ACFIXJIJDZMPPO-NNYOXOHSSA-N 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 239000007983 Tris buffer Substances 0.000 claims 1
- HWXBTNAVRSUOJR-UHFFFAOYSA-N alpha-hydroxyglutaric acid Natural products OC(=O)C(O)CCC(O)=O HWXBTNAVRSUOJR-UHFFFAOYSA-N 0.000 claims 1
- 229940009533 alpha-ketoglutaric acid Drugs 0.000 claims 1
- 239000013060 biological fluid Substances 0.000 claims 1
- 239000000470 constituent Substances 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims 1
- 235000019796 monopotassium phosphate Nutrition 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 claims 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 claims 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical class OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/527—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/008—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions for determining co-enzymes or co-factors, e.g. NAD, ATP
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/50—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving creatine phosphokinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/52—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving transaminase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/58—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US561757A US3413198A (en) | 1966-06-30 | 1966-06-30 | Reagents and method for assaying biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL28098A true IL28098A (en) | 1976-02-29 |
Family
ID=24243318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL28098A IL28098A (en) | 1966-06-30 | 1967-06-01 | Stable reagent mixtures containing polyhydric compounds |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US3413198A (enExample) |
| BE (1) | BE700778A (enExample) |
| CH (1) | CH514841A (enExample) |
| DE (3) | DE1598321A1 (enExample) |
| GB (3) | GB1163409A (enExample) |
| IL (1) | IL28098A (enExample) |
| NL (1) | NL6708570A (enExample) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3523871A (en) * | 1966-07-20 | 1970-08-11 | Eisai Co Ltd | Stabilization of catalase |
| DE2050267C3 (de) * | 1970-10-13 | 1974-06-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von stabilen Zubereitungen von reduziertem Nicotinamidadenindinucleotid |
| BE786291A (fr) * | 1971-07-20 | 1973-01-15 | Technicon Instr | Compositions de diagnostic pour determination de la glutamate-oxalate-transaminase (got) et de la glutamate-pyruvate-transaminase (gpt) |
| US3928137A (en) * | 1971-10-20 | 1975-12-23 | Mallinckrodt Inc | Reagent formulation for uric acid assay |
| US3953295A (en) * | 1971-10-20 | 1976-04-27 | Mallinckrodt, Inc. | Reagent formulations for glucose assay |
| US3926735A (en) * | 1971-10-20 | 1975-12-16 | Mallinckrodt Inc | Alkaline phosphatase assay |
| CS164231B2 (enExample) * | 1972-09-28 | 1975-11-07 | ||
| US3953297A (en) * | 1973-02-26 | 1976-04-27 | Pierce Chemical Company | Determination of amylase |
| US3869348A (en) * | 1973-02-26 | 1975-03-04 | Pierce Chemical Co | Determination of amylase |
| US3941659A (en) * | 1974-07-11 | 1976-03-02 | Honeywell Inc. | Blood alcohol analyzer |
| US3982999A (en) * | 1974-07-26 | 1976-09-28 | Kharasch Jerome A | Complexing cresolase with copper chelating agents |
| US3926736A (en) * | 1974-08-30 | 1975-12-16 | Calbiochem | Enzymatic ethanol assay |
| US4067773A (en) * | 1975-09-02 | 1978-01-10 | William Zinsser & Co. | Enzyme-containing article for removing paper adhered to a surface |
| US4006061A (en) * | 1975-12-29 | 1977-02-01 | Monsanto Company | Lactate dehydrogenase determination method |
| CH625626A5 (en) * | 1976-03-25 | 1981-09-30 | Hoffmann La Roche | Process for the preparation of stable immunological reagents |
| US4105800A (en) * | 1976-07-26 | 1978-08-08 | Board Of Regents For Education Of The State Of Rhode Island | Immobilized enzyme method to assess fish quality |
| US4080263A (en) * | 1976-08-11 | 1978-03-21 | Boehringer Mannheim Gmbh | Process and reagent for the rapid quantitative determination of lactate or alanine |
| NL7610608A (nl) * | 1976-09-24 | 1978-03-29 | Akzo Nv | Werkwijze voor het stabiliseren van peroxidase- -bevattende composities. |
| US4127502A (en) * | 1977-06-10 | 1978-11-28 | Eastman Kodak Company | Stabilizers for reconstituted, lyophilized samples |
| SE7905852L (sv) * | 1979-07-04 | 1981-01-05 | Lkb Produkter Ab | Forfarande for bestemning av kreatinkinas |
| SE432112B (sv) * | 1979-07-12 | 1984-03-19 | Lkb Produkter Ab | Forfarande for bestemning av kreatinkinas i prover innehallande atp |
| US4465770A (en) * | 1979-09-11 | 1984-08-14 | Modrovich Ivan Endre | Stabilized enzymic solutions for determining urea |
| US4282316A (en) * | 1979-09-11 | 1981-08-04 | Modrovich Ivan Endre | Stabilized enzymic solutions for determining urea |
| US4378430A (en) * | 1979-09-11 | 1983-03-29 | Modrovich Ivan Endre | Method of forming stabilized urease solutions |
| US4394449A (en) * | 1980-02-13 | 1983-07-19 | Modrovich Ivan Endre | Stabilization of coenzymes in aqueous solution |
| US4425427A (en) | 1980-03-13 | 1984-01-10 | Vitafin N.V. | Simultaneous, kinetic, spectrophotometric analysis of blood serum for multiple components |
| US4321364A (en) * | 1980-04-17 | 1982-03-23 | Minister For Public Works For The State Of New South Wales | Preparation of soluble chromogenic substrates |
| JPS56169598A (en) * | 1980-05-26 | 1981-12-26 | Mitsubishi Petrochem Co Ltd | Measuring composition |
| CA1164340A (en) * | 1980-09-02 | 1984-03-27 | Alex A. Monte | Single test compositions for immunoassays |
| DE3044454C2 (de) * | 1980-11-26 | 1982-12-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisierte Enzymzubereitung |
| US4366243A (en) * | 1981-04-17 | 1982-12-28 | Miles Laboratories, Inc. | Stabilization of glucose oxidase apoenzyme |
| DK388982A (da) * | 1981-09-01 | 1983-03-02 | Sturge John & E Ltd | Stabiliserede lactaseoploesninger og fremgangsmaade til stabilisering deraf |
| JPS58209993A (ja) * | 1982-05-31 | 1983-12-07 | Mochida Pharmaceut Co Ltd | インタ−フエロンの産生方法 |
| DE3303098A1 (de) * | 1983-01-31 | 1984-08-02 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren und reagenz zur glucosebestimmung im haemolysierten blut |
| US4663295A (en) * | 1983-06-29 | 1987-05-05 | Ciba Corning Diagnostics Corp. | Estrogen-progesterone control reagents and methods for making same |
| US4734360A (en) * | 1983-07-12 | 1988-03-29 | Lifescan, Inc. | Colorimetric ethanol analysis method and test device |
| US4900666A (en) * | 1983-07-12 | 1990-02-13 | Lifescan, Inc. | Colorimetric ethanol analysis method and test device |
| US4810633A (en) * | 1984-06-04 | 1989-03-07 | Miles Inc. | Enzymatic ethanol test |
| FI78117C (fi) * | 1984-06-25 | 1989-06-12 | Suomen Sokeri Oy | Foerfarande foer framstaellning av ett stabilt glukosisomeraskoncentrat. |
| DK8502857A (enExample) * | 1984-06-25 | 1985-12-26 | ||
| JPS6188899A (ja) * | 1984-10-05 | 1986-05-07 | Unitika Ltd | クレアチンキナ−ゼ定量用試薬 |
| CH664975A5 (fr) * | 1985-03-15 | 1988-04-15 | Battelle Memorial Institute | Procede analytique pour la determination d'un coenzyme reduit. |
| DE3525648A1 (de) * | 1985-07-18 | 1987-01-29 | Bokel Heinz Hermann Dr | 1-oxa-2-oxo-2-r-3-aza-5-z-cyclopentanderivate |
| US5009994A (en) * | 1986-03-24 | 1991-04-23 | Em Diagnostic Systems, Inc. | Particles containing mannitol suitable for tabletting into diagnostic reagents |
| US4820627A (en) * | 1986-03-24 | 1989-04-11 | Em Diagnostic Systems, Inc. | Method of preparing particles suitable for tabletting into diagnostic reagents |
| US4755461A (en) * | 1986-04-17 | 1988-07-05 | Bio/Data Corporation | Tableted blood plasma microconcentrated thromboplastin coagulation reagent |
| US4935346A (en) | 1986-08-13 | 1990-06-19 | Lifescan, Inc. | Minimum procedure system for the determination of analytes |
| US4990445A (en) * | 1988-01-20 | 1991-02-05 | Beckman Instruments, Inc. | Stable reagent and kinetic assay for alpha-amylase |
| GB8826429D0 (en) * | 1988-11-11 | 1988-12-14 | Univ Leeds Ind Service Ltd | Enzyme stabilisation systems |
| GB8903593D0 (en) * | 1989-02-16 | 1989-04-05 | Pafra Ltd | Storage of materials |
| USRE38385E1 (en) * | 1989-02-16 | 2004-01-13 | Nektar Therapeutics | Storage of materials |
| DE4103220A1 (de) * | 1991-02-02 | 1992-08-06 | Boehringer Mannheim Gmbh | Verfahren zur stabilisierung von 1-methylhydantoinase, verwendung einer stabilisierten 1-methylhydantoinase zur bestimmung eines analyten, entsprechendes bestimmungsverfahren sowie hierfuer geeignete mittel |
| AU659645B2 (en) | 1991-06-26 | 1995-05-25 | Inhale Therapeutic Systems | Storage of materials |
| US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| US6309671B1 (en) | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
| US6458326B1 (en) | 1999-11-24 | 2002-10-01 | Home Diagnostics, Inc. | Protective test strip platform |
| US6525330B2 (en) | 2001-02-28 | 2003-02-25 | Home Diagnostics, Inc. | Method of strip insertion detection |
| US6541266B2 (en) | 2001-02-28 | 2003-04-01 | Home Diagnostics, Inc. | Method for determining concentration of an analyte in a test strip |
| US6562625B2 (en) | 2001-02-28 | 2003-05-13 | Home Diagnostics, Inc. | Distinguishing test types through spectral analysis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE683524C (de) * | 1934-07-08 | 1939-11-09 | Max Winckel Dr | Verfahren zur UEberfuehrung von Loesungen chemisch labiler Stoffe in Trockenform |
| US3072532A (en) * | 1958-11-04 | 1963-01-08 | Innerfield Irving | Administration of enzymic composition |
| US2990338A (en) * | 1959-11-24 | 1961-06-27 | Gibson Jacob John | Composition for determination of glucose in body fluids |
| US3133001A (en) * | 1959-11-26 | 1964-05-12 | Muset Pedro Puig | Stabilization of enzymes |
-
1966
- 1966-06-30 US US561757A patent/US3413198A/en not_active Expired - Lifetime
-
1967
- 1967-06-01 IL IL28098A patent/IL28098A/en unknown
- 1967-06-20 NL NL6708570A patent/NL6708570A/xx unknown
- 1967-06-28 GB GB29940/67A patent/GB1163409A/en not_active Expired
- 1967-06-28 GB GB29939/67A patent/GB1192046A/en not_active Expired
- 1967-06-28 GB GB29934/67A patent/GB1191697A/en not_active Expired
- 1967-06-28 CH CH913967A patent/CH514841A/de not_active IP Right Cessation
- 1967-06-30 DE DE19671598321 patent/DE1598321A1/de active Pending
- 1967-06-30 DE DE19671598326 patent/DE1598326A1/de active Pending
- 1967-06-30 DE DE1598325A patent/DE1598325B1/de active Granted
- 1967-06-30 BE BE700778D patent/BE700778A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1191697A (en) | 1970-05-13 |
| GB1163409A (en) | 1969-09-04 |
| DE1598325B1 (de) | 1973-01-11 |
| BE700778A (enExample) | 1968-01-02 |
| NL6708570A (enExample) | 1968-01-02 |
| CH514841A (de) | 1971-10-31 |
| GB1192046A (en) | 1970-05-13 |
| US3413198A (en) | 1968-11-26 |
| DE1598326A1 (de) | 1972-03-02 |
| DE1598321A1 (de) | 1972-02-24 |
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