IL27006A - N-benzimidazolyl carbamic acid esters and anthelmintic compositions containing them - Google Patents
N-benzimidazolyl carbamic acid esters and anthelmintic compositions containing themInfo
- Publication number
- IL27006A IL27006A IL27006A IL2700666A IL27006A IL 27006 A IL27006 A IL 27006A IL 27006 A IL27006 A IL 27006A IL 2700666 A IL2700666 A IL 2700666A IL 27006 A IL27006 A IL 27006A
- Authority
- IL
- Israel
- Prior art keywords
- acid esters
- compositions containing
- carbamic acid
- anthelmintic compositions
- benzimidazolyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38752464A | 1964-08-04 | 1964-08-04 | |
US51612065A | 1965-12-23 | 1965-12-23 | |
US56211766A | 1966-07-01 | 1966-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL27006A true IL27006A (en) | 1971-04-28 |
Family
ID=27409808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL27006A IL27006A (en) | 1964-08-04 | 1966-12-04 | N-benzimidazolyl carbamic acid esters and anthelmintic compositions containing them |
Country Status (15)
Country | Link |
---|---|
US (1) | US3574845A (de) |
BE (2) | BE666795A (de) |
BR (1) | BR6685587D0 (de) |
CH (1) | CH479590A (de) |
CY (1) | CY621A (de) |
DE (1) | DE1795799A1 (de) |
DK (1) | DK130586B (de) |
FI (1) | FI46962C (de) |
FR (3) | FR4648M (de) |
GB (3) | GB1096190A (de) |
IL (1) | IL27006A (de) |
IT (2) | IT1043764B (de) |
NL (1) | NL153535B (de) |
NO (1) | NO120582B (de) |
SE (1) | SE342819B (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3541213A (en) * | 1966-05-06 | 1970-11-17 | Du Pont | Fungicidal and mite ovicidal substituted 2-aminobenzimidazoles |
DK131821C (da) * | 1967-03-22 | 1976-03-08 | Smith Kline French Lab | Analogifremgangsmade til fremstilling af en 2-karbalkoksyaminobenzimidazol |
US3997553A (en) * | 1969-06-25 | 1976-12-14 | E. I. Du Pont De Nemours And Company | 2-Benzimidazolecarbamic acid esters by the cyanamide process |
US3694454A (en) * | 1970-07-17 | 1972-09-26 | Boehringer Sohn Ingelheim | 1-{8 1{40 -carboxylic acylamino-2{40 ,2{40 ,2{40 -trichloro)-ethyl{9 -2-(hydrocarbyloxycarbonyl-amino)-benzimidazoles |
US3852460A (en) * | 1971-01-06 | 1974-12-03 | C Littler | Acid salts of 2-benzimidazolecarbamic acid, alkyl esters as fungicides |
US3929821A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives |
CA1032171A (en) * | 1972-12-29 | 1978-05-30 | Colin C. Beard | 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3965113A (en) * | 1972-12-29 | 1976-06-22 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3929824A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3993769A (en) * | 1972-12-29 | 1976-11-23 | Syntex (U.S.A.) Inc. | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4046906A (en) * | 1973-04-21 | 1977-09-06 | Hoechst Aktiengesellschaft | Salts of alkyl 2-benzimidazole-carbamate |
US4258198A (en) * | 1973-05-29 | 1981-03-24 | Smithkline Corporation | 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles |
US3969526A (en) * | 1973-05-29 | 1976-07-13 | Smithkline Corporation | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles |
US3901901A (en) * | 1973-06-19 | 1975-08-26 | Syntex Inc | 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3962437A (en) * | 1973-06-19 | 1976-06-08 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
DE2348104A1 (de) * | 1973-09-25 | 1975-04-03 | Hoechst Ag | Anthelmintisch wirksame 2-carbalkoxyamino-benzimidazolyl-5(6)-amino-phenylaether und verfahren zu ihrer herstellung |
US3929823A (en) * | 1973-11-21 | 1975-12-30 | Syntex Inc | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
HU169503B (de) * | 1974-02-05 | 1976-12-28 | ||
US3915986A (en) * | 1974-06-19 | 1975-10-28 | Smithkline Corp | Methyl 5-propylthio-2-benzimidazolecarbamate |
DE2432631A1 (de) * | 1974-07-06 | 1976-01-22 | Hoechst Ag | 5-phenylsulfinyl-2-benzimidazol-carbaminsaeureester und verfahren zu ihrer herstellung |
DE2441201C2 (de) * | 1974-08-28 | 1986-08-07 | Hoechst Ag, 6230 Frankfurt | Anthelminthisch wirksame 2-Carbalkoxyamino-5(6)-phenyl-sulfonyloxy-benzimidazole und Verfahren zu ihrer Herstellung |
DE2441202C2 (de) * | 1974-08-28 | 1986-05-28 | Hoechst Ag, 6230 Frankfurt | 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonsäure-phenylester, Verfahren zu ihrer Herstellung und diese enthaltende anthelmintische Mittel |
US3993768A (en) * | 1974-11-25 | 1976-11-23 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4025638A (en) * | 1975-03-10 | 1977-05-24 | Smithkline Corporation | Methods and compositions using 5-cycloalkylthio- and oxy-2-carbalkoxy-aminobenzimidazole |
US4076828A (en) * | 1977-02-17 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles |
US4076827A (en) * | 1977-04-28 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles |
US4076825A (en) * | 1977-06-22 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles |
SE443977B (sv) * | 1977-05-10 | 1986-03-17 | Chinoin Gyogyszer Es Vegyeszet | Forfarande for framstellning av 5(6)-tio-bensimidazolderivat |
US4152522A (en) * | 1978-01-03 | 1979-05-01 | Ethyl Corporation | Process for the preparation of 2-benzimidazole carbamates |
US4136174A (en) * | 1978-01-18 | 1979-01-23 | E. R. Squibb & Sons, Inc. | Benzimidazolecarbamates and method |
US4156006A (en) * | 1978-01-09 | 1979-05-22 | E. R. Squibb & Sons, Inc. | Vinyl sulfide derivatives of benzimidazoles |
US4154846A (en) * | 1978-06-16 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates |
US4174400A (en) * | 1978-09-13 | 1979-11-13 | Merck & Co., Inc. | Anthelmintic benzimidazoles |
DE2840927A1 (de) * | 1978-09-20 | 1980-04-10 | Bayer Ag | 3,4-dihydroisochinoline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
US4487936A (en) * | 1979-12-04 | 1984-12-11 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Preparation of alkylthiobenzimidazoles |
US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
US4656276A (en) * | 1980-08-07 | 1987-04-07 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4661593A (en) * | 1980-08-07 | 1987-04-28 | Angus Chemcial Company | Quinoxaline adducts useful as anthelmintics |
US4348389A (en) * | 1980-08-07 | 1982-09-07 | International Minerals & Chemical Corp. | Quinoxaline adducts useful as anthelmintics |
US4720548A (en) * | 1980-08-07 | 1988-01-19 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4629790A (en) * | 1980-08-07 | 1986-12-16 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4658028A (en) * | 1980-08-07 | 1987-04-14 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
GB9124002D0 (en) * | 1991-11-12 | 1992-01-02 | Pfizer Ltd | Benzimidazole anthelmintic agents |
US6262093B1 (en) | 1995-04-12 | 2001-07-17 | The Proctor & Gamble Company | Methods of treating cancer with benzimidazoles |
US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
US6506783B1 (en) | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
US6423734B1 (en) * | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
US6608096B1 (en) * | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
US6462062B1 (en) * | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
US6380232B1 (en) | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
US7893271B2 (en) * | 2005-07-28 | 2011-02-22 | Intervet International B.V. | Benzimidazole carbamates and (thio) carbamates, and the synthesis and use thereof |
EP2032046B1 (de) * | 2006-06-12 | 2015-11-04 | Smith & Nephew, Inc. | Systeme und vorrichtungen zur schienbeingeweberesektion |
CA2660647C (en) | 2006-06-14 | 2015-07-28 | Intervet International B.V. | A suspension comprising benzimidazole carbamate and a polysorbate |
CN108884054B (zh) | 2015-11-30 | 2022-08-02 | 儿童医学中心公司 | 用于治疗增殖性疾病的化合物 |
JP2023519882A (ja) | 2020-03-27 | 2023-05-15 | ソム、イノベーション、バイオテック、ソシエダッド、アノニマ | シヌクレイノパチーの治療に有用な化合物 |
-
1965
- 1965-07-13 BE BE666795D patent/BE666795A/xx unknown
- 1965-07-30 GB GB32818/65A patent/GB1096190A/en not_active Expired
- 1965-08-04 FR FR27162A patent/FR4648M/fr not_active Expired
-
1966
- 1966-07-01 US US562117A patent/US3574845A/en not_active Expired - Lifetime
- 1966-07-06 GB GB30428/66A patent/GB1114069A/en not_active Expired
- 1966-12-04 IL IL27006A patent/IL27006A/xx unknown
- 1966-12-08 DK DK636566AA patent/DK130586B/da unknown
- 1966-12-19 GB GB56839/66A patent/GB1123317A/en not_active Expired
- 1966-12-19 CH CH1816466A patent/CH479590A/de not_active IP Right Cessation
- 1966-12-20 FI FI663382A patent/FI46962C/fi active
- 1966-12-21 BR BR185587/66A patent/BR6685587D0/pt unknown
- 1966-12-22 BE BE691611D patent/BE691611A/xx not_active IP Right Cessation
- 1966-12-22 DE DE19661795799 patent/DE1795799A1/de active Pending
- 1966-12-22 FR FR88435A patent/FR5840M/fr not_active Expired
- 1966-12-22 NO NO166120A patent/NO120582B/no unknown
- 1966-12-22 IT IT31439/66A patent/IT1043764B/it active
- 1966-12-22 SE SE17580/66A patent/SE342819B/xx unknown
- 1966-12-22 FR FR88441A patent/FR1510235A/fr not_active Expired
- 1966-12-23 NL NL666618109A patent/NL153535B/xx not_active IP Right Cessation
-
1967
- 1967-05-26 IT IT16552/67A patent/IT1056714B/it active
-
1971
- 1971-11-19 CY CY62171A patent/CY621A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US3574845A (en) | 1971-04-13 |
FI46962B (de) | 1973-05-02 |
BE666795A (de) | 1966-01-13 |
IT1043764B (it) | 1980-02-29 |
GB1096190A (en) | 1967-12-20 |
DK130586C (de) | 1975-08-18 |
GB1114069A (en) | 1968-05-15 |
FR5840M (de) | 1968-03-04 |
DK130586B (da) | 1975-03-10 |
DE1795799A1 (de) | 1975-10-02 |
BR6685587D0 (pt) | 1973-12-27 |
FR1510235A (fr) | 1968-01-19 |
BE691611A (fr) | 1967-06-22 |
DE1620439B2 (de) | 1975-12-18 |
CY621A (en) | 1971-11-19 |
CH479590A (de) | 1969-10-15 |
FR4648M (de) | 1966-12-05 |
IT1056714B (it) | 1982-02-20 |
GB1123317A (en) | 1968-08-14 |
NL153535B (nl) | 1977-06-15 |
DE1620439A1 (de) | 1970-04-23 |
FI46962C (fi) | 1973-08-10 |
NO120582B (de) | 1970-11-09 |
SE342819B (de) | 1972-02-21 |
NL6618109A (de) | 1967-06-26 |
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