FR1510235A - Esters d'acides benzimidazolyl carbamiques et leur procédé de préparation - Google Patents
Esters d'acides benzimidazolyl carbamiques et leur procédé de préparationInfo
- Publication number
- FR1510235A FR1510235A FR88441A FR88441A FR1510235A FR 1510235 A FR1510235 A FR 1510235A FR 88441 A FR88441 A FR 88441A FR 88441 A FR88441 A FR 88441A FR 1510235 A FR1510235 A FR 1510235A
- Authority
- FR
- France
- Prior art keywords
- esters
- preparation
- carbamic acids
- benzimidazolyl
- benzimidazolyl carbamic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38752464A | 1964-08-04 | 1964-08-04 | |
US51612065A | 1965-12-23 | 1965-12-23 | |
US56211766A | 1966-07-01 | 1966-07-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
FR1510235A true FR1510235A (fr) | 1968-01-19 |
Family
ID=27409808
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR27162A Expired FR4648M (fr) | 1964-08-04 | 1965-08-04 | |
FR88441A Expired FR1510235A (fr) | 1964-08-04 | 1966-12-22 | Esters d'acides benzimidazolyl carbamiques et leur procédé de préparation |
FR88435A Expired FR5840M (fr) | 1964-08-04 | 1966-12-22 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR27162A Expired FR4648M (fr) | 1964-08-04 | 1965-08-04 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR88435A Expired FR5840M (fr) | 1964-08-04 | 1966-12-22 |
Country Status (15)
Country | Link |
---|---|
US (1) | US3574845A (fr) |
BE (2) | BE666795A (fr) |
BR (1) | BR6685587D0 (fr) |
CH (1) | CH479590A (fr) |
CY (1) | CY621A (fr) |
DE (1) | DE1795799A1 (fr) |
DK (1) | DK130586B (fr) |
FI (1) | FI46962C (fr) |
FR (3) | FR4648M (fr) |
GB (3) | GB1096190A (fr) |
IL (1) | IL27006A (fr) |
IT (2) | IT1043764B (fr) |
NL (1) | NL153535B (fr) |
NO (1) | NO120582B (fr) |
SE (1) | SE342819B (fr) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3541213A (en) * | 1966-05-06 | 1970-11-17 | Du Pont | Fungicidal and mite ovicidal substituted 2-aminobenzimidazoles |
DK131821C (da) * | 1967-03-22 | 1976-03-08 | Smith Kline French Lab | Analogifremgangsmade til fremstilling af en 2-karbalkoksyaminobenzimidazol |
US3997553A (en) * | 1969-06-25 | 1976-12-14 | E. I. Du Pont De Nemours And Company | 2-Benzimidazolecarbamic acid esters by the cyanamide process |
US3694454A (en) * | 1970-07-17 | 1972-09-26 | Boehringer Sohn Ingelheim | 1-{8 1{40 -carboxylic acylamino-2{40 ,2{40 ,2{40 -trichloro)-ethyl{9 -2-(hydrocarbyloxycarbonyl-amino)-benzimidazoles |
US3852460A (en) * | 1971-01-06 | 1974-12-03 | C Littler | Acid salts of 2-benzimidazolecarbamic acid, alkyl esters as fungicides |
CA1032171A (fr) * | 1972-12-29 | 1978-05-30 | Colin C. Beard | Noyau benzene 5-6 substitue par des derives benzimidazole -2- carbamate a action authelonintique |
US3965113A (en) * | 1972-12-29 | 1976-06-22 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3929824A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3929821A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives |
US3993769A (en) * | 1972-12-29 | 1976-11-23 | Syntex (U.S.A.) Inc. | 1,5(6)-Disubstituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4046906A (en) * | 1973-04-21 | 1977-09-06 | Hoechst Aktiengesellschaft | Salts of alkyl 2-benzimidazole-carbamate |
US3969526A (en) * | 1973-05-29 | 1976-07-13 | Smithkline Corporation | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles |
US4258198A (en) * | 1973-05-29 | 1981-03-24 | Smithkline Corporation | 5-Cycloalkyl thio- and oxy-2-carbalkoxyaminobenzimidazoles |
US3962437A (en) * | 1973-06-19 | 1976-06-08 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3901901A (en) * | 1973-06-19 | 1975-08-26 | Syntex Inc | 5(6)-benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
DE2348104A1 (de) * | 1973-09-25 | 1975-04-03 | Hoechst Ag | Anthelmintisch wirksame 2-carbalkoxyamino-benzimidazolyl-5(6)-amino-phenylaether und verfahren zu ihrer herstellung |
US3929823A (en) * | 1973-11-21 | 1975-12-30 | Syntex Inc | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
HU169503B (fr) * | 1974-02-05 | 1976-12-28 | ||
US3915986A (en) * | 1974-06-19 | 1975-10-28 | Smithkline Corp | Methyl 5-propylthio-2-benzimidazolecarbamate |
DE2432631A1 (de) * | 1974-07-06 | 1976-01-22 | Hoechst Ag | 5-phenylsulfinyl-2-benzimidazol-carbaminsaeureester und verfahren zu ihrer herstellung |
DE2441201C2 (de) * | 1974-08-28 | 1986-08-07 | Hoechst Ag, 6230 Frankfurt | Anthelminthisch wirksame 2-Carbalkoxyamino-5(6)-phenyl-sulfonyloxy-benzimidazole und Verfahren zu ihrer Herstellung |
DE2441202C2 (de) * | 1974-08-28 | 1986-05-28 | Hoechst Ag, 6230 Frankfurt | 2-Carbalkoxyamino-benzimidazolyl-5(6)-sulfonsäure-phenylester, Verfahren zu ihrer Herstellung und diese enthaltende anthelmintische Mittel |
US3993768A (en) * | 1974-11-25 | 1976-11-23 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US4025638A (en) * | 1975-03-10 | 1977-05-24 | Smithkline Corporation | Methods and compositions using 5-cycloalkylthio- and oxy-2-carbalkoxy-aminobenzimidazole |
US4076825A (en) * | 1977-06-22 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles |
US4076828A (en) * | 1977-02-17 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles |
US4076827A (en) * | 1977-04-28 | 1978-02-28 | E. R. Squibb & Sons, Inc. | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles |
SE443977B (sv) * | 1977-05-10 | 1986-03-17 | Chinoin Gyogyszer Es Vegyeszet | Forfarande for framstellning av 5(6)-tio-bensimidazolderivat |
US4152522A (en) * | 1978-01-03 | 1979-05-01 | Ethyl Corporation | Process for the preparation of 2-benzimidazole carbamates |
US4136174A (en) * | 1978-01-18 | 1979-01-23 | E. R. Squibb & Sons, Inc. | Benzimidazolecarbamates and method |
US4156006A (en) * | 1978-01-09 | 1979-05-22 | E. R. Squibb & Sons, Inc. | Vinyl sulfide derivatives of benzimidazoles |
US4154846A (en) * | 1978-06-16 | 1979-05-15 | E. R. Squibb & Sons, Inc. | Substituted thio-, sulfinyl-, and sulfonyl-alkyl benzimidazole carbamates |
US4174400A (en) * | 1978-09-13 | 1979-11-13 | Merck & Co., Inc. | Anthelmintic benzimidazoles |
DE2840927A1 (de) * | 1978-09-20 | 1980-04-10 | Bayer Ag | 3,4-dihydroisochinoline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
US4487936A (en) * | 1979-12-04 | 1984-12-11 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Preparation of alkylthiobenzimidazoles |
US4299837A (en) | 1979-12-05 | 1981-11-10 | Montedison S.P.A. | Anthelmintic benzimidazole-carbamates |
US4656276A (en) * | 1980-08-07 | 1987-04-07 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4629790A (en) * | 1980-08-07 | 1986-12-16 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4658028A (en) * | 1980-08-07 | 1987-04-14 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4720548A (en) * | 1980-08-07 | 1988-01-19 | Angus Chemical Company | Quinoxaline adducts useful as anthelmintics |
US4661593A (en) * | 1980-08-07 | 1987-04-28 | Angus Chemcial Company | Quinoxaline adducts useful as anthelmintics |
US4348389A (en) * | 1980-08-07 | 1982-09-07 | International Minerals & Chemical Corp. | Quinoxaline adducts useful as anthelmintics |
GB9124002D0 (en) * | 1991-11-12 | 1992-01-02 | Pfizer Ltd | Benzimidazole anthelmintic agents |
US6262093B1 (en) | 1995-04-12 | 2001-07-17 | The Proctor & Gamble Company | Methods of treating cancer with benzimidazoles |
US6479526B1 (en) | 1995-04-12 | 2002-11-12 | The Procter & Gamble Company | Pharmaceutical composition for inhibiting the growth of viruses and cancers |
US6506783B1 (en) * | 1997-05-16 | 2003-01-14 | The Procter & Gamble Company | Cancer treatments and pharmaceutical compositions therefor |
US6423734B1 (en) * | 1999-08-13 | 2002-07-23 | The Procter & Gamble Company | Method of preventing cancer |
US6462062B1 (en) * | 2000-09-26 | 2002-10-08 | The Procter & Gamble Company | Compounds and methods for use thereof in the treatment of cancer or viral infections |
US6380232B1 (en) | 2000-09-26 | 2002-04-30 | The Procter & Gamble Company | Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof |
US6608096B1 (en) * | 2000-09-26 | 2003-08-19 | University Of Arizona Foundation | Compounds and methods for use thereof in the treatment of cancer or viral infections |
PL1913009T3 (pl) * | 2005-07-28 | 2010-10-29 | Intervet Int Bv | Nowe (tio)karbaminiany benzimidazolu o działaniu przeciwpasożytniczym i sposób ich wytwarzania |
WO2008091358A1 (fr) * | 2006-06-12 | 2008-07-31 | Smith And Nephew Inc | Systèmes, procédés et dispositifs pour une résection tibiale |
EP2037914B1 (fr) | 2006-06-14 | 2013-10-23 | Intervet International BV | Une suspension comprenant un carbamate de benzimidazole et un polysorbate |
CA3043549C (fr) | 2015-11-30 | 2023-11-21 | Children's Medical Center Corporation | Composes pour traiter des maladies proliferatives |
US20230147129A1 (en) | 2020-03-27 | 2023-05-11 | Som Innovation Biotech, S.A. | Compounds for use in the treatment of synucleinopathies |
-
1965
- 1965-07-13 BE BE666795D patent/BE666795A/xx unknown
- 1965-07-30 GB GB32818/65A patent/GB1096190A/en not_active Expired
- 1965-08-04 FR FR27162A patent/FR4648M/fr not_active Expired
-
1966
- 1966-07-01 US US562117A patent/US3574845A/en not_active Expired - Lifetime
- 1966-07-06 GB GB30428/66A patent/GB1114069A/en not_active Expired
- 1966-12-04 IL IL27006A patent/IL27006A/xx unknown
- 1966-12-08 DK DK636566AA patent/DK130586B/da unknown
- 1966-12-19 CH CH1816466A patent/CH479590A/de not_active IP Right Cessation
- 1966-12-19 GB GB56839/66A patent/GB1123317A/en not_active Expired
- 1966-12-20 FI FI663382A patent/FI46962C/fi active
- 1966-12-21 BR BR185587/66A patent/BR6685587D0/pt unknown
- 1966-12-22 BE BE691611D patent/BE691611A/fr not_active IP Right Cessation
- 1966-12-22 DE DE19661795799 patent/DE1795799A1/de active Pending
- 1966-12-22 NO NO166120A patent/NO120582B/no unknown
- 1966-12-22 IT IT31439/66A patent/IT1043764B/it active
- 1966-12-22 FR FR88441A patent/FR1510235A/fr not_active Expired
- 1966-12-22 FR FR88435A patent/FR5840M/fr not_active Expired
- 1966-12-22 SE SE17580/66A patent/SE342819B/xx unknown
- 1966-12-23 NL NL666618109A patent/NL153535B/xx not_active IP Right Cessation
-
1967
- 1967-05-26 IT IT16552/67A patent/IT1056714B/it active
-
1971
- 1971-11-19 CY CY62171A patent/CY621A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CY621A (en) | 1971-11-19 |
IL27006A (en) | 1971-04-28 |
NL6618109A (fr) | 1967-06-26 |
BE666795A (fr) | 1966-01-13 |
IT1043764B (it) | 1980-02-29 |
GB1096190A (en) | 1967-12-20 |
DK130586B (da) | 1975-03-10 |
NL153535B (nl) | 1977-06-15 |
FR5840M (fr) | 1968-03-04 |
GB1123317A (en) | 1968-08-14 |
IT1056714B (it) | 1982-02-20 |
FI46962B (fr) | 1973-05-02 |
BE691611A (fr) | 1967-06-22 |
FR4648M (fr) | 1966-12-05 |
DK130586C (fr) | 1975-08-18 |
GB1114069A (en) | 1968-05-15 |
US3574845A (en) | 1971-04-13 |
SE342819B (fr) | 1972-02-21 |
DE1795799A1 (de) | 1975-10-02 |
FI46962C (fi) | 1973-08-10 |
CH479590A (de) | 1969-10-15 |
NO120582B (fr) | 1970-11-09 |
DE1620439A1 (de) | 1970-04-23 |
BR6685587D0 (pt) | 1973-12-27 |
DE1620439B2 (de) | 1975-12-18 |
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