FR1504439A - Esters d'acides alpha-(3-indolyl) aliphatiques inférieurs et leur procédé de fabrication - Google Patents

Esters d'acides alpha-(3-indolyl) aliphatiques inférieurs et leur procédé de fabrication

Info

Publication number
FR1504439A
FR1504439A FR42443A FR42443A FR1504439A FR 1504439 A FR1504439 A FR 1504439A FR 42443 A FR42443 A FR 42443A FR 42443 A FR42443 A FR 42443A FR 1504439 A FR1504439 A FR 1504439A
Authority
FR
France
Prior art keywords
indolyl
esters
manufacture
aliphatic acids
lower alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR42443A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of FR1504439A publication Critical patent/FR1504439A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR42443A 1964-12-31 1965-12-15 Esters d'acides alpha-(3-indolyl) aliphatiques inférieurs et leur procédé de fabrication Expired FR1504439A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US422567A US3271394A (en) 1964-12-31 1964-12-31 Alpha-indolyl-3-acetic acid esters

Publications (1)

Publication Number Publication Date
FR1504439A true FR1504439A (fr) 1967-12-08

Family

ID=23675442

Family Applications (2)

Application Number Title Priority Date Filing Date
FR42443A Expired FR1504439A (fr) 1964-12-31 1965-12-15 Esters d'acides alpha-(3-indolyl) aliphatiques inférieurs et leur procédé de fabrication
FR53371A Expired FR5919M (fr) 1964-12-31 1966-03-14

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR53371A Expired FR5919M (fr) 1964-12-31 1966-03-14

Country Status (7)

Country Link
US (1) US3271394A (fr)
BR (1) BR6575773D0 (fr)
CH (1) CH481103A (fr)
DE (1) DE1595972A1 (fr)
FR (2) FR1504439A (fr)
GB (1) GB1126636A (fr)
NL (1) NL6517257A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE313567B (fr) * 1966-07-13 1969-08-18 Sumitomo Chemical Co
US3535334A (en) * 1966-12-07 1970-10-20 Sumitomo Chemical Co 1-piperonoyl-3-indolyl aliphatic acid derivatives
JPS52156862A (en) * 1976-06-22 1977-12-27 Hisamitsu Pharmaceut Co Inc Novel indoleacetic acid ester derivatives
US4778787A (en) * 1985-12-20 1988-10-18 Trustees Of Boston University Method for treatment of angina and myocardial infarctions with omental lipids
JP2002504933A (ja) * 1997-06-30 2002-02-12 タイム ブロック インコーポレイテッド 皮膚の老化及び傷の治療に用いられる細胞移動剤
US20070161698A1 (en) * 2003-05-30 2007-07-12 Microbia, Inc. Modulators of CRTH2 Activity
CA2530808A1 (fr) * 2003-07-01 2005-01-13 Microbia, Inc. Inhibiteurs cox-2 et faah
WO2005037227A2 (fr) * 2003-10-16 2005-04-28 Microbia, Inc. Inhibiteurs selectifs de la cox-2
US20050234030A1 (en) * 2004-04-20 2005-10-20 Wilmin Bartolini Modulators of CRTH2, COX-2 and FAAH
US20050234244A1 (en) * 2004-04-20 2005-10-20 Wilmin Bartolini Synthesis of COX-2 and FAAH inhibitors
CN111960986A (zh) * 2019-05-19 2020-11-20 河南东泰制药有限公司 一种阿西美辛的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren

Also Published As

Publication number Publication date
US3271394A (en) 1966-09-06
BR6575773D0 (pt) 1973-12-27
NL6517257A (fr) 1966-07-04
FR5919M (fr) 1968-04-01
CH481103A (de) 1969-11-15
DE1595972A1 (de) 1970-02-19
GB1126636A (en) 1968-09-11

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