IL265560B - Pharmaceutical composition comprising mineralocorticoid receptor antagonist and use thereof - Google Patents
Pharmaceutical composition comprising mineralocorticoid receptor antagonist and use thereofInfo
- Publication number
- IL265560B IL265560B IL265560A IL26556019A IL265560B IL 265560 B IL265560 B IL 265560B IL 265560 A IL265560 A IL 265560A IL 26556019 A IL26556019 A IL 26556019A IL 265560 B IL265560 B IL 265560B
- Authority
- IL
- Israel
- Prior art keywords
- compound
- pharmaceutical composition
- optionally
- ranges
- daily dose
- Prior art date
Links
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Pharmacology & Pharmacy (AREA)
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- Engineering & Computer Science (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
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- Molecular Biology (AREA)
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Applications Claiming Priority (2)
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| CN201610849142 | 2016-09-24 | ||
| PCT/CN2017/102969 WO2018054357A1 (zh) | 2016-09-24 | 2017-09-22 | 含盐皮质激素受体拮抗剂的药物组合物及其用途 |
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| IL265560A IL265560A (en) | 2019-05-30 |
| IL265560B true IL265560B (en) | 2022-07-01 |
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| IL265560A IL265560B (en) | 2016-09-24 | 2017-09-22 | Pharmaceutical composition comprising mineralocorticoid receptor antagonist and use thereof |
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| PE (1) | PE20190608A1 (enExample) |
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| WO (1) | WO2018054357A1 (enExample) |
| ZA (1) | ZA201901740B (enExample) |
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| UA123464C2 (uk) | 2016-09-24 | 2021-04-07 | Кейбіпі Байосайєнсіз Ко., Лтд. | Фармацевтична композиція, яка містить антагоніст мінералокортикоїдних рецепторів, та її застосування |
| CN113425683B (zh) * | 2021-08-19 | 2022-09-20 | 谢彩华 | 一种三氮脒缓释注射剂及其制备方法 |
| CN116492336B (zh) * | 2023-04-04 | 2024-07-05 | 迪沙药业集团有限公司 | 一种坎地沙坦酯药物组合物 |
| CN120168468B (zh) * | 2025-03-05 | 2025-10-17 | 苏州天马医药集团天吉生物制药有限公司 | 一种非奈利酮制剂及其制备方法 |
Citations (2)
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| EP2607363A1 (en) * | 2010-08-18 | 2013-06-26 | KBP Biosciences Co., Ltd. | Fused ring compound for use as mineralocorticoid receptor antagonist |
| EP2937348A1 (en) * | 2012-12-22 | 2015-10-28 | KBP Biosciences Co., Ltd. | Crystal form of compound used as mineralocorticoid receptor antagonist and preparation method therefor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| HUP0700395A2 (en) | 2007-06-07 | 2009-03-02 | Sanofi Aventis | Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates |
| TWI431010B (zh) * | 2007-12-19 | 2014-03-21 | Lilly Co Eli | 礦皮質素受體拮抗劑及使用方法 |
| KR20210124532A (ko) * | 2010-02-25 | 2021-10-14 | 브리스톨-마이어스 스퀴브 홀딩스 아일랜드 언리미티드 컴퍼니 | 아픽사반 제제 |
| CA2814371C (en) * | 2010-10-29 | 2019-03-19 | Algiax Pharmaceuticals Gmbh | Use of malononitrilamides in neuropathic pain |
| UA123464C2 (uk) | 2016-09-24 | 2021-04-07 | Кейбіпі Байосайєнсіз Ко., Лтд. | Фармацевтична композиція, яка містить антагоніст мінералокортикоїдних рецепторів, та її застосування |
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2017
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- 2017-09-22 BR BR112019005214A patent/BR112019005214A2/pt not_active Application Discontinuation
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- 2017-09-22 IL IL265560A patent/IL265560B/en unknown
- 2017-09-22 RU RU2019110341A patent/RU2725153C1/ru active
- 2017-09-22 WO PCT/CN2017/102969 patent/WO2018054357A1/zh not_active Ceased
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- 2017-09-22 PE PE2019000668A patent/PE20190608A1/es unknown
- 2017-09-22 KR KR1020197009917A patent/KR102226516B1/ko not_active Expired - Fee Related
- 2017-09-25 TW TW109132042A patent/TWI780488B/zh active
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2019
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2021
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2023
- 2023-09-26 US US18/372,968 patent/US20240016796A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2607363A1 (en) * | 2010-08-18 | 2013-06-26 | KBP Biosciences Co., Ltd. | Fused ring compound for use as mineralocorticoid receptor antagonist |
| EP2937348A1 (en) * | 2012-12-22 | 2015-10-28 | KBP Biosciences Co., Ltd. | Crystal form of compound used as mineralocorticoid receptor antagonist and preparation method therefor |
Non-Patent Citations (2)
| Title |
|---|
| DOMENIC A. SICA,, HYPERKALEMIA RISK IN CHRONIC KIDNEY DISEASE : DETERRENT TO THE USE OF ALDOSTERONE RECEPTOR ANTAGONISM OR NOT, 1 May 2009 (2009-05-01) * |
| NAIR AB AND JACOB S,, A SIMPLE PRACTICE GUIDE FOR DOSE CONVERSION BETWEEN ANIMALS AND HUMAN, 31 May 2016 (2016-05-31) * |
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