HK1258622A1 - 含鹽皮質激素受體拮抗劑的藥物組合物及其用途 - Google Patents

含鹽皮質激素受體拮抗劑的藥物組合物及其用途

Info

Publication number
HK1258622A1
HK1258622A1 HK19100983.8A HK19100983A HK1258622A1 HK 1258622 A1 HK1258622 A1 HK 1258622A1 HK 19100983 A HK19100983 A HK 19100983A HK 1258622 A1 HK1258622 A1 HK 1258622A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical composition
receptor antagonist
mineralocorticoid receptor
mineralocorticoid
antagonist
Prior art date
Application number
HK19100983.8A
Other languages
English (en)
Inventor
Zhenhua Huang
Xiaocui Guo
Original Assignee
山東亨利醫藥科技有限責任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 山東亨利醫藥科技有限責任公司 filed Critical 山東亨利醫藥科技有限責任公司
Publication of HK1258622A1 publication Critical patent/HK1258622A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HK19100983.8A 2016-09-24 2019-01-21 含鹽皮質激素受體拮抗劑的藥物組合物及其用途 HK1258622A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610849142 2016-09-24
PCT/CN2017/102969 WO2018054357A1 (zh) 2016-09-24 2017-09-22 含盐皮质激素受体拮抗剂的药物组合物及其用途

Publications (1)

Publication Number Publication Date
HK1258622A1 true HK1258622A1 (zh) 2019-11-15

Family

ID=61689352

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19100983.8A HK1258622A1 (zh) 2016-09-24 2019-01-21 含鹽皮質激素受體拮抗劑的藥物組合物及其用途

Country Status (30)

Country Link
US (2) US11806344B2 (zh)
EP (1) EP3517113A4 (zh)
JP (2) JP7090599B2 (zh)
KR (1) KR102226516B1 (zh)
CN (1) CN109069502B (zh)
AU (1) AU2017329549B2 (zh)
BR (1) BR112019005214A2 (zh)
CA (1) CA3037588C (zh)
CL (1) CL2019000753A1 (zh)
CO (1) CO2019003808A2 (zh)
CR (2) CR20190203A (zh)
CU (1) CU24569B1 (zh)
DO (1) DOP2019000072A (zh)
EA (1) EA201990668A1 (zh)
EC (1) ECSP19027578A (zh)
HK (1) HK1258622A1 (zh)
IL (1) IL265560B (zh)
MA (1) MA45202B1 (zh)
MX (1) MX2019003339A (zh)
MY (1) MY195054A (zh)
NZ (1) NZ751901A (zh)
PE (1) PE20190608A1 (zh)
PH (1) PH12019500516A1 (zh)
RU (2) RU2725153C1 (zh)
SG (1) SG10201912389WA (zh)
TN (1) TN2019000063A1 (zh)
TW (2) TWI715806B (zh)
UA (1) UA123464C2 (zh)
WO (1) WO2018054357A1 (zh)
ZA (1) ZA201901740B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY195054A (en) 2016-09-24 2023-01-05 Kbp Biosciences Co Ltd Pharmaceutical Composition Comprising Mineralocorticoid Receptor Antagonist and use Thereof
CN113425683B (zh) * 2021-08-19 2022-09-20 谢彩华 一种三氮脒缓释注射剂及其制备方法
CN116492336B (zh) * 2023-04-04 2024-07-05 迪沙药业集团有限公司 一种坎地沙坦酯药物组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0700395A2 (en) 2007-06-07 2009-03-02 Sanofi Aventis Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates
PE20091057A1 (es) * 2007-12-19 2009-07-20 Lilly Co Eli Antagonistas del receptor mineralcorticoide y metodos de uso
JP5846647B2 (ja) * 2010-02-25 2016-01-20 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ アピキサバン製剤
CN102372710A (zh) * 2010-08-18 2012-03-14 山东轩竹医药科技有限公司 作为盐皮质激素受体拮抗剂的并环类化合物
DK2632451T3 (en) * 2010-10-29 2017-12-18 Algiax Pharmaceuticals Gmbh USE OF MALONNITRILAMIDS IN NEUROPATHIC PAIN
EP3954688A1 (en) * 2012-12-22 2022-02-16 Kbp Biosciences Pte. Ltd. Crystal forms of compound used as mineralocorticoid receptor antagonist and methods for their preparation
MY195054A (en) 2016-09-24 2023-01-05 Kbp Biosciences Co Ltd Pharmaceutical Composition Comprising Mineralocorticoid Receptor Antagonist and use Thereof

Also Published As

Publication number Publication date
PH12019500516A1 (en) 2020-02-24
ECSP19027578A (es) 2019-07-31
US20190201390A1 (en) 2019-07-04
TW201813645A (zh) 2018-04-16
TWI780488B (zh) 2022-10-11
MA45202B1 (fr) 2022-04-29
CN109069502B (zh) 2021-08-06
NZ751901A (en) 2021-07-30
CR20190203A (es) 2019-06-26
EA201990668A1 (ru) 2019-10-31
US20240016796A1 (en) 2024-01-18
ZA201901740B (en) 2019-10-30
MA45202A1 (fr) 2020-11-30
UA123464C2 (uk) 2021-04-07
TW202100156A (zh) 2021-01-01
TN2019000063A1 (en) 2020-07-15
WO2018054357A1 (zh) 2018-03-29
KR102226516B1 (ko) 2021-03-12
CL2019000753A1 (es) 2019-07-19
AU2017329549A1 (en) 2019-04-11
JP7090599B2 (ja) 2022-06-24
AU2017329549B2 (en) 2020-05-14
JP2019532939A (ja) 2019-11-14
CU24569B1 (es) 2022-01-13
JP2022037044A (ja) 2022-03-08
TWI715806B (zh) 2021-01-11
CU20190023A7 (es) 2019-11-04
MX2019003339A (es) 2019-06-03
IL265560A (en) 2019-05-30
CN109069502A (zh) 2018-12-21
EP3517113A4 (en) 2020-07-08
CR20240015A (es) 2024-04-05
EP3517113A1 (en) 2019-07-31
DOP2019000072A (es) 2019-06-16
RU2020120876A (ru) 2020-08-26
US11806344B2 (en) 2023-11-07
IL265560B (en) 2022-07-01
CA3037588C (en) 2022-07-12
SG10201912389WA (en) 2020-02-27
BR112019005214A2 (pt) 2019-06-11
PE20190608A1 (es) 2019-04-23
RU2020120876A3 (zh) 2020-12-28
MY195054A (en) 2023-01-05
RU2725153C1 (ru) 2020-06-30
RU2750667C2 (ru) 2021-06-30
CA3037588A1 (en) 2018-03-29
CO2019003808A2 (es) 2019-04-30
KR20190057323A (ko) 2019-05-28

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