IL260846A - - Google Patents

Info

Publication number
IL260846A
IL260846A IL26084618A IL26084618A IL260846A IL 260846 A IL260846 A IL 260846A IL 26084618 A IL26084618 A IL 26084618A IL 26084618 A IL26084618 A IL 26084618A IL 260846 A IL260846 A IL 260846A
Authority
IL
Israel
Application number
IL26084618A
Other languages
English (en)
Other versions
IL260846B2 (en
IL260846B (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of IL260846A publication Critical patent/IL260846A/en
Publication of IL260846B publication Critical patent/IL260846B/en
Publication of IL260846B2 publication Critical patent/IL260846B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
IL260846A 2016-01-29 2018-07-29 Antigen binding proteins that bind pd-l1 IL260846B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662288912P 2016-01-29 2016-01-29
PCT/US2017/015429 WO2017132562A1 (en) 2016-01-29 2017-01-27 Antigen binding proteins that bind pd-l1

Publications (3)

Publication Number Publication Date
IL260846A true IL260846A (https=) 2018-09-20
IL260846B IL260846B (en) 2022-10-01
IL260846B2 IL260846B2 (en) 2023-02-01

Family

ID=59386438

Family Applications (1)

Application Number Title Priority Date Filing Date
IL260846A IL260846B2 (en) 2016-01-29 2018-07-29 Antigen binding proteins that bind pd-l1

Country Status (17)

Country Link
US (4) US10118963B2 (https=)
EP (1) EP3408400B1 (https=)
JP (3) JP6883590B2 (https=)
KR (2) KR20260041830A (https=)
CN (2) CN116333124A (https=)
AU (1) AU2017212717B2 (https=)
BR (1) BR112018015480A2 (https=)
CA (1) CA3013051A1 (https=)
CL (1) CL2018002034A1 (https=)
EA (1) EA037855B1 (https=)
ES (1) ES2986360T3 (https=)
IL (1) IL260846B2 (https=)
MX (2) MX2018009228A (https=)
PH (1) PH12018501611A1 (https=)
SG (1) SG11201806496SA (https=)
TW (1) TWI760323B (https=)
WO (1) WO2017132562A1 (https=)

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HK1204557A1 (en) * 2012-05-31 2015-11-27 Sorrento Therapeutics, Inc. Antigen binding proteins that bind pd-l1
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
EA037855B1 (ru) 2016-01-29 2021-05-27 Сорренто Терапьютикс, Инк. Полностью человеческое антитело класса igg, связывающееся с эпитопом pd-l1
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
EP3534947A1 (en) 2016-11-03 2019-09-11 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses & methods
CN119899267A (zh) * 2018-03-22 2025-04-29 赛因格先进生物技术弗朗哥塞尔瓦托有限责任公司 拮抗性pd-1、pd-l1和lag-3结合蛋白
AU2018418224B2 (en) 2018-04-09 2025-04-17 Oricell Therapeutics Co., Ltd. Anti-PD-L1 antibody and use thereof
WO2019227490A1 (en) 2018-06-01 2019-12-05 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and methods for imaging
KR20210056288A (ko) * 2018-06-01 2021-05-18 타유 후아시아 바이오테크 메디컬 그룹 컴퍼니 리미티드 질환 또는 병태를 치료하기 위한 조성물 및 그의 용도
US12391758B2 (en) 2018-08-20 2025-08-19 1Globe Biomedical Co., Ltd. Anti-PD-L1 cancer immunotherapy antibodies
EP3893902B1 (en) * 2018-12-11 2024-10-23 Sanford Burnham Prebys Medical Discovery Institute Inhibitors of pd-l1 activity or expression for use in the treatment of serrated colorectal cancer
WO2020151572A1 (en) 2019-01-23 2020-07-30 Tayu Huaxia Biotech Medical Group Co., Ltd. Anti-pd-l1 diabodies and the use thereof
WO2020215020A1 (en) * 2019-04-18 2020-10-22 Qlsf Biotherapeutics Inc. Humanized anti-pd-l1 antibodies
WO2021037007A1 (zh) * 2019-08-29 2021-03-04 荣昌生物制药(烟台)股份有限公司 抗pd-l1抗体及其应用
MX2023000005A (es) * 2020-06-26 2023-03-06 Sorrento Therapeutics Inc Virus del herpes simple (vhs) oncolíticos que expresan proteínas de fusión inmunomoduladoras.
EP4208204A1 (en) 2020-09-02 2023-07-12 Mayo Foundation for Medical Education and Research Antibody-nanoparticle complexes and methods for making and using the same
JP2023552694A (ja) 2020-11-16 2023-12-19 イミューンオンシア セラピューティクス インコーポレイテッド 免疫抗がん剤に対する治療反応性を予測するためのバイオマーカーおよびその用途
MX2023012995A (es) 2021-05-07 2023-12-14 Immuneoncia Therapeutics Inc Anticuerpo biespecífico que se enlaza específicamente a cd47 y pd-l1.
US20240279339A1 (en) 2021-06-09 2024-08-22 Vivasor, Inc. Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device
CA3267341A1 (en) * 2022-09-19 2024-03-28 Sonoma Biotherapeutics, Inc. Specific chimeric antigen receptors for a citrullinated antigen to target regulatory T lymphocytes for the treatment of hidradenitis suppurativa
WO2024160721A1 (en) 2023-01-30 2024-08-08 Kymab Limited Antibodies
TW202544031A (zh) * 2024-02-29 2025-11-16 南韓商柳韓洋行股份有限公司 抗tigit/抗pd-l1雙特異性抗體及其用途
IL323020A (en) * 2024-04-13 2026-03-01 Immuneoncia Therapeutics Inc Neoadjuvant immunotherapy with a PD-L1 inhibitor for cancer treatment
KR20250165706A (ko) 2024-04-13 2025-11-27 주식회사 이뮨온시아 암 치료를 위한 pd-l1 저해제를 이용한 신보조요법

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Also Published As

Publication number Publication date
MX2022011659A (es) 2022-10-13
CN109715821B (zh) 2022-09-06
JP2019507183A (ja) 2019-03-14
US20190092861A1 (en) 2019-03-28
ES2986360T3 (es) 2024-11-11
MX2018009228A (es) 2019-07-08
CN116333124A (zh) 2023-06-27
JP6883590B2 (ja) 2021-06-09
US20210147539A1 (en) 2021-05-20
JP2021102633A (ja) 2021-07-15
EA201891709A1 (ru) 2019-01-31
TWI760323B (zh) 2022-04-11
BR112018015480A2 (pt) 2019-05-21
PH12018501611A1 (en) 2019-04-08
US10118963B2 (en) 2018-11-06
TW201736400A (zh) 2017-10-16
KR20190026642A (ko) 2019-03-13
WO2017132562A1 (en) 2017-08-03
IL260846B2 (en) 2023-02-01
JP2022095910A (ja) 2022-06-28
US20240190959A1 (en) 2024-06-13
EA037855B1 (ru) 2021-05-27
CN109715821A (zh) 2019-05-03
US11919952B2 (en) 2024-03-05
WO2017132562A8 (en) 2017-09-08
AU2017212717B2 (en) 2023-11-16
KR20260041830A (ko) 2026-03-27
EP3408400C0 (en) 2024-06-26
KR102927822B1 (ko) 2026-02-13
AU2017212717A1 (en) 2018-09-06
EP3408400A1 (en) 2018-12-05
EP3408400A4 (en) 2019-11-27
NZ745357A (en) 2025-08-29
US20170218066A1 (en) 2017-08-03
CL2018002034A1 (es) 2019-03-15
IL260846B (en) 2022-10-01
SG11201806496SA (en) 2018-08-30
JP7140867B2 (ja) 2022-09-21
EP3408400B1 (en) 2024-06-26
US10919964B2 (en) 2021-02-16
CA3013051A1 (en) 2017-08-03

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