IL260846A - - Google Patents

Info

Publication number
IL260846A
IL260846A IL26084618A IL26084618A IL260846A IL 260846 A IL260846 A IL 260846A IL 26084618 A IL26084618 A IL 26084618A IL 26084618 A IL26084618 A IL 26084618A IL 260846 A IL260846 A IL 260846A
Authority
IL
Israel
Application number
IL26084618A
Other languages
English (en)
Other versions
IL260846B (en
IL260846B2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of IL260846A publication Critical patent/IL260846A/en
Publication of IL260846B publication Critical patent/IL260846B/en
Publication of IL260846B2 publication Critical patent/IL260846B2/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
IL260846A 2016-01-29 2018-07-29 Antigen binding proteins that bind pd-l1 IL260846B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662288912P 2016-01-29 2016-01-29
PCT/US2017/015429 WO2017132562A1 (en) 2016-01-29 2017-01-27 Antigen binding proteins that bind pd-l1

Publications (3)

Publication Number Publication Date
IL260846A true IL260846A (https=) 2018-09-20
IL260846B IL260846B (en) 2022-10-01
IL260846B2 IL260846B2 (en) 2023-02-01

Family

ID=59386438

Family Applications (1)

Application Number Title Priority Date Filing Date
IL260846A IL260846B2 (en) 2016-01-29 2018-07-29 Antigen binding proteins that bind pd-l1

Country Status (17)

Country Link
US (4) US10118963B2 (https=)
EP (1) EP3408400B1 (https=)
JP (3) JP6883590B2 (https=)
KR (2) KR102927822B1 (https=)
CN (2) CN109715821B (https=)
AU (1) AU2017212717B2 (https=)
BR (1) BR112018015480A2 (https=)
CA (1) CA3013051A1 (https=)
CL (1) CL2018002034A1 (https=)
EA (1) EA037855B1 (https=)
ES (1) ES2986360T3 (https=)
IL (1) IL260846B2 (https=)
MX (2) MX2018009228A (https=)
PH (1) PH12018501611A1 (https=)
SG (1) SG11201806496SA (https=)
TW (1) TWI760323B (https=)
WO (1) WO2017132562A1 (https=)

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KR20220084444A (ko) 2012-05-31 2022-06-21 소렌토 쎄라퓨틱스, 인코포레이티드 Pd-l1에 결합하는 항원 결합 단백질
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
WO2017132562A1 (en) * 2016-01-29 2017-08-03 Heyue Zhou Antigen binding proteins that bind pd-l1
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
RU2769282C2 (ru) 2016-06-20 2022-03-30 Кимаб Лимитед Анти-PD-L1 и IL-2 цитокины
EP3534947A1 (en) 2016-11-03 2019-09-11 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses & methods
MX2020009550A (es) * 2018-03-22 2020-11-11 Keires Ag Proteinas de union a antigeno antagonistas.
MX2020010653A (es) 2018-04-09 2020-10-28 Origincell Therapeutics Co Ltd Anticuerpo anti-muerte programada-ligando 1 y su uso.
EP3818085A4 (en) * 2018-06-01 2022-03-09 Tayu Huaxia Biotech Medical Group Co., Ltd. COMPOSITIONS AND THEIR USES FOR THE TREATMENT OF DISEASES OR DISORDERS
WO2019227490A1 (en) 2018-06-01 2019-12-05 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and methods for imaging
MX2021002077A (es) * 2018-08-20 2021-05-27 1Globe Biomedical Co Ltd Nuevas composiciones de anticuerpos para la inmunoterapia contra el cáncer.
US20220177561A1 (en) * 2018-12-11 2022-06-09 Sanford Burnham Prebys Medical Discovery Institute Models and Methods Useful for the Treatment of Serrated Colorectal Cancer
CN113795511B (zh) 2019-01-23 2024-07-23 大有华夏生物医药集团有限公司 抗pd-l1双抗体及其用途
JP7725066B2 (ja) * 2019-04-18 2025-08-19 キューエルエスエフ バイオセラピューティック インコーポレイテッド ヒト化抗pd-l1抗体
KR20220012856A (ko) * 2019-08-29 2022-02-04 레메젠 코, 리미티드 항 pd―l1 항체 및 그의 용도
JP2023532279A (ja) * 2020-06-26 2023-07-27 ソレント・セラピューティクス・インコーポレイテッド 免疫調節性融合タンパク質を発現する腫瘍溶解性単純ヘルペスウイルス(hsv)
EP4208204A1 (en) 2020-09-02 2023-07-12 Mayo Foundation for Medical Education and Research Antibody-nanoparticle complexes and methods for making and using the same
TWI907564B (zh) 2020-11-16 2025-12-11 南韓商益免安協公司 用於預測對免疫抗癌劑的治療反應的生物標誌物及其用途
CA3219221A1 (en) * 2021-05-07 2022-11-10 Immuneoncia Therapeutics, Inc. Bispecific antibody specifically binding to cd47 and pd-l1
WO2022261262A1 (en) 2021-06-09 2022-12-15 Sorrento Therapeutics, Inc. Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device
US20260083777A1 (en) * 2022-09-19 2026-03-26 Sonoma Biotherapeutics, Inc. Citrullinated antigen-specific chimeric antigen receptors for targeting regulatory t cells to treat hidradenitis suppurativa
CN120813375A (zh) 2023-01-30 2025-10-17 凯玛布有限公司 抗体
WO2025183487A1 (en) * 2024-02-29 2025-09-04 Yuhan Corporation Anti-tigit/anti-pd-l1 bispecific antibody and use thereof
CN121175334A (zh) 2024-04-13 2025-12-19 益免安协公司 在治疗癌症中的使用pd-l1抑制剂的新辅助免疫疗法

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Also Published As

Publication number Publication date
PH12018501611A1 (en) 2019-04-08
US20170218066A1 (en) 2017-08-03
CN116333124A (zh) 2023-06-27
TW201736400A (zh) 2017-10-16
BR112018015480A2 (pt) 2019-05-21
JP7140867B2 (ja) 2022-09-21
JP2022095910A (ja) 2022-06-28
CN109715821A (zh) 2019-05-03
CA3013051A1 (en) 2017-08-03
EA201891709A1 (ru) 2019-01-31
US11919952B2 (en) 2024-03-05
JP6883590B2 (ja) 2021-06-09
EA037855B1 (ru) 2021-05-27
AU2017212717B2 (en) 2023-11-16
US20210147539A1 (en) 2021-05-20
SG11201806496SA (en) 2018-08-30
JP2021102633A (ja) 2021-07-15
US20240190959A1 (en) 2024-06-13
CN109715821B (zh) 2022-09-06
CL2018002034A1 (es) 2019-03-15
TWI760323B (zh) 2022-04-11
EP3408400B1 (en) 2024-06-26
ES2986360T3 (es) 2024-11-11
NZ745357A (en) 2025-08-29
AU2017212717A1 (en) 2018-09-06
EP3408400C0 (en) 2024-06-26
US10919964B2 (en) 2021-02-16
JP2019507183A (ja) 2019-03-14
WO2017132562A8 (en) 2017-09-08
EP3408400A4 (en) 2019-11-27
US10118963B2 (en) 2018-11-06
KR20190026642A (ko) 2019-03-13
WO2017132562A1 (en) 2017-08-03
EP3408400A1 (en) 2018-12-05
KR102927822B1 (ko) 2026-02-13
IL260846B (en) 2022-10-01
US20190092861A1 (en) 2019-03-28
MX2018009228A (es) 2019-07-08
KR20260041830A (ko) 2026-03-27
IL260846B2 (en) 2023-02-01
MX2022011659A (es) 2022-10-13

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