IL247531B - The history of ksuz, their preparation and uses - Google Patents

The history of ksuz, their preparation and uses

Info

Publication number
IL247531B
IL247531B IL247531A IL24753116A IL247531B IL 247531 B IL247531 B IL 247531B IL 247531 A IL247531 A IL 247531A IL 24753116 A IL24753116 A IL 24753116A IL 247531 B IL247531 B IL 247531B
Authority
IL
Israel
Prior art keywords
preparation
hexose derivatives
hexose
derivatives
Prior art date
Application number
IL247531A
Other languages
English (en)
Hebrew (he)
Other versions
IL247531A0 (en
Original Assignee
Faculdade De Ciencias Da Univ De Lisboa
Instituto De Tecnologia Quim E Biologica Antonio Xavier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Faculdade De Ciencias Da Univ De Lisboa, Instituto De Tecnologia Quim E Biologica Antonio Xavier filed Critical Faculdade De Ciencias Da Univ De Lisboa
Publication of IL247531A0 publication Critical patent/IL247531A0/en
Publication of IL247531B publication Critical patent/IL247531B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Saccharide Compounds (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL247531A 2014-03-14 2016-08-29 The history of ksuz, their preparation and uses IL247531B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461953392P 2014-03-14 2014-03-14
PCT/PT2015/050001 WO2015137838A1 (en) 2014-03-14 2015-03-13 Hexose derivatives, preparation and uses thereof

Publications (2)

Publication Number Publication Date
IL247531A0 IL247531A0 (en) 2016-11-30
IL247531B true IL247531B (en) 2021-04-29

Family

ID=53264710

Family Applications (1)

Application Number Title Priority Date Filing Date
IL247531A IL247531B (en) 2014-03-14 2016-08-29 The history of ksuz, their preparation and uses

Country Status (12)

Country Link
US (2) US11708387B2 (https=)
EP (1) EP3116886A1 (https=)
JP (2) JP7067867B2 (https=)
KR (3) KR102651029B1 (https=)
CN (2) CN106573952A (https=)
BR (1) BR112016021231B1 (https=)
CA (1) CA2942635C (https=)
IL (1) IL247531B (https=)
MX (1) MX386787B (https=)
RU (1) RU2731563C2 (https=)
SG (2) SG10201807891UA (https=)
WO (1) WO2015137838A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102651029B1 (ko) * 2014-03-14 2024-03-25 파쿠우다지 지 씨엔씨아스 다 우니베르시다지 지 리스보아 헥소스 유도체, 그의 제제 및 용도
FR3061013B1 (fr) * 2016-12-22 2020-04-17 Greenpharma Composition contenant le digeneaside, son procede d'obtention et son utilisation cosmetique, veterinaire ou nutraceutique
US12098162B2 (en) * 2017-11-13 2024-09-24 Extremochem, Lda Neutral glycosylated amides and dianionic glucuronidated acids as stabilizers for biological molecules
CN116251110B (zh) * 2022-11-18 2025-02-14 广东药科大学 β-D-吡喃葡萄糖基-乳酸及其衍生物在制备治疗代谢性疾病、炎症药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060099567A1 (en) * 2004-04-08 2006-05-11 Biomatrica, Inc. Integration of sample storage and sample management for life science
DE102004031588A1 (de) * 2004-06-30 2006-02-09 Symrise Gmbh & Co. Kg Verwendung von Äpfelsäureglucosiden als Geschmacksstoffe
PT103442A (pt) * 2006-02-24 2007-08-31 Stab Vida Investigacao E Servi Derivados sintéticos de manosil-glicerato para a estabilização e/ou preservação de biomateriais
PT103441A (pt) 2006-02-24 2007-08-24 Stab Vida Investigacao E Servi Utilização de solutos compatíveis para melhorar o desempenho de técnicas utilizando materiais biológicos imobilizados
DE102010038496A1 (de) 2010-07-27 2012-02-02 Henkel Ag & Co. Kgaa Stabilisierte flüssige enzymhaltige Tensidzubereitung
DE102011118027A1 (de) * 2011-09-12 2013-03-14 Henkel Ag & Co. Kgaa Verfahren zur Anpassung eines Hydrolytischen Enzyms an eine das hydrolytische Enzym stabilisierende Komponente
KR102651029B1 (ko) 2014-03-14 2024-03-25 파쿠우다지 지 씨엔씨아스 다 우니베르시다지 지 리스보아 헥소스 유도체, 그의 제제 및 용도
JP2020097767A (ja) 2018-12-18 2020-06-25 株式会社東芝 表面処理剤、これを用いた積層体、及び無電解めっき製品

Also Published As

Publication number Publication date
SG11201607530XA (en) 2016-10-28
BR112016021231B1 (pt) 2021-07-27
KR102401853B1 (ko) 2022-05-25
US12590117B2 (en) 2026-03-31
JP7077361B2 (ja) 2022-05-30
US20230357301A1 (en) 2023-11-09
IL247531A0 (en) 2016-11-30
CA2942635A1 (en) 2015-09-17
KR20220153571A (ko) 2022-11-18
KR20240045328A (ko) 2024-04-05
JP2017516838A (ja) 2017-06-22
SG10201807891UA (en) 2018-10-30
EP3116886A1 (en) 2017-01-18
MX386787B (es) 2025-03-19
US20180170955A1 (en) 2018-06-21
JP2020183383A (ja) 2020-11-12
CA2942635C (en) 2022-12-06
RU2016140337A3 (https=) 2018-10-30
CN106573952A (zh) 2017-04-19
KR20160145584A (ko) 2016-12-20
BR112016021231A2 (en) 2018-07-10
KR102651029B1 (ko) 2024-03-25
CN115448964A (zh) 2022-12-09
US11708387B2 (en) 2023-07-25
KR102828884B1 (ko) 2025-07-02
JP7067867B2 (ja) 2022-05-16
MX2016011808A (es) 2017-05-09
RU2016140337A (ru) 2018-04-17
RU2731563C2 (ru) 2020-09-04
WO2015137838A1 (en) 2015-09-17

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Legal Events

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FF Patent granted