IL244731B - From a repeated day of microtecovirimate monohydrate - Google Patents

From a repeated day of microtecovirimate monohydrate

Info

Publication number
IL244731B
IL244731B IL244731A IL24473116A IL244731B IL 244731 B IL244731 B IL 244731B IL 244731 A IL244731 A IL 244731A IL 24473116 A IL24473116 A IL 24473116A IL 244731 B IL244731 B IL 244731B
Authority
IL
Israel
Prior art keywords
rehydration
micronized
tecovirimat
monohydrate
tecovirimat monohydrate
Prior art date
Application number
IL244731A
Other languages
English (en)
Hebrew (he)
Other versions
IL244731A0 (en
Original Assignee
Siga Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siga Tech Inc filed Critical Siga Tech Inc
Publication of IL244731A0 publication Critical patent/IL244731A0/en
Publication of IL244731B publication Critical patent/IL244731B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035Isoindoles, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL244731A 2013-11-19 2016-03-23 From a repeated day of microtecovirimate monohydrate IL244731B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361906119P 2013-11-19 2013-11-19
PCT/US2014/065674 WO2015077143A1 (en) 2013-11-19 2014-11-14 Rehydration of micronized tecovirimat monohydrate

Publications (2)

Publication Number Publication Date
IL244731A0 IL244731A0 (en) 2016-04-21
IL244731B true IL244731B (en) 2021-05-31

Family

ID=53180052

Family Applications (2)

Application Number Title Priority Date Filing Date
IL244731A IL244731B (en) 2013-11-19 2016-03-23 From a repeated day of microtecovirimate monohydrate
IL282098A IL282098B2 (en) 2013-11-19 2021-04-06 From a repeated day of microtecovirimate monohydrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL282098A IL282098B2 (en) 2013-11-19 2021-04-06 From a repeated day of microtecovirimate monohydrate

Country Status (8)

Country Link
US (2) US10406103B2 (enExample)
EP (1) EP3043793B1 (enExample)
JP (1) JP6594303B2 (enExample)
CN (1) CN105636585B (enExample)
AU (2) AU2014353235B2 (enExample)
CA (1) CA2930461C (enExample)
IL (2) IL244731B (enExample)
WO (1) WO2015077143A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020252284A1 (en) * 2019-06-13 2020-12-17 Imbucanna, Inc Compressible cannabinoid pharmaceutical composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
US7687641B2 (en) * 2003-06-20 2010-03-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
US7737168B2 (en) * 2003-06-20 2010-06-15 Siga Technologies, Inc. Compounds, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
UA97349C2 (uk) * 2005-09-08 2012-02-10 Х. Луннбэк А/С Стійкі тверді склади сертиндолу
CA2685153C (en) * 2007-04-23 2014-12-16 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
CN101445478B (zh) 2008-08-22 2011-04-06 中国人民解放军军事医学科学院生物工程研究所 含一个结晶水的化合物st-246及其晶体与制备方法
JP2011041888A (ja) * 2009-08-20 2011-03-03 Nippon Soda Co Ltd ジェットミル粉砕条件の最適化方法
EP2549871B1 (en) * 2010-03-23 2018-08-22 Siga Technologies, Inc. Polymorphic form st-246 and methods of preparation
SG10202105262QA (en) * 2010-08-05 2021-06-29 Siga Technologies Inc St-246 liquid formulations and methods

Also Published As

Publication number Publication date
IL282098A (en) 2021-05-31
CN105636585B (zh) 2020-02-07
EP3043793A1 (en) 2016-07-20
JP2016537318A (ja) 2016-12-01
EP3043793B1 (en) 2021-01-06
CN105636585A (zh) 2016-06-01
CA2930461C (en) 2022-08-16
AU2014353235A1 (en) 2016-04-21
JP6594303B2 (ja) 2019-10-23
CA2930461A1 (en) 2015-05-28
IL282098B1 (en) 2023-01-01
AU2019208252B2 (en) 2020-03-19
WO2015077143A1 (en) 2015-05-28
AU2014353235B2 (en) 2019-05-09
US10716759B2 (en) 2020-07-21
IL244731A0 (en) 2016-04-21
US10406103B2 (en) 2019-09-10
US20160235676A1 (en) 2016-08-18
IL282098B2 (en) 2023-05-01
EP3043793A4 (en) 2017-05-10
US20190380966A1 (en) 2019-12-19
AU2019208252A1 (en) 2019-08-15

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Legal Events

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FF Patent granted