PL3071575T3 - Wytwarzanie normorfinanów - Google Patents

Wytwarzanie normorfinanów

Info

Publication number
PL3071575T3
PL3071575T3 PL14862986T PL14862986T PL3071575T3 PL 3071575 T3 PL3071575 T3 PL 3071575T3 PL 14862986 T PL14862986 T PL 14862986T PL 14862986 T PL14862986 T PL 14862986T PL 3071575 T3 PL3071575 T3 PL 3071575T3
Authority
PL
Poland
Prior art keywords
normorphinans
preparation
Prior art date
Application number
PL14862986T
Other languages
English (en)
Inventor
John Brandt
Subo Liao
Edmund C. Hudson
Esa T. Jarvi
Peter X. Wang
Michael Schaefer
Original Assignee
SpecGx LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SpecGx LLC filed Critical SpecGx LLC
Publication of PL3071575T3 publication Critical patent/PL3071575T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL14862986T 2013-11-18 2014-11-18 Wytwarzanie normorfinanów PL3071575T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361905312P 2013-11-18 2013-11-18
PCT/US2014/066152 WO2015074049A1 (en) 2013-11-18 2014-11-18 Preparation of normorphinans
EP14862986.8A EP3071575B1 (en) 2013-11-18 2014-11-18 Preparation of normorphinans

Publications (1)

Publication Number Publication Date
PL3071575T3 true PL3071575T3 (pl) 2020-06-01

Family

ID=53058181

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14862986T PL3071575T3 (pl) 2013-11-18 2014-11-18 Wytwarzanie normorfinanów

Country Status (10)

Country Link
US (1) US9127009B2 (pl)
EP (1) EP3071575B1 (pl)
JP (1) JP6389252B2 (pl)
AU (1) AU2014348256B2 (pl)
BR (1) BR112016010098A2 (pl)
CA (1) CA2928205C (pl)
ES (1) ES2770591T3 (pl)
MX (1) MX371334B (pl)
PL (1) PL3071575T3 (pl)
WO (1) WO2015074049A1 (pl)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002006275A1 (en) * 2000-07-17 2002-01-24 Smithkline Beecham P.L.C. Novel processes for the preparation of 4-phenylpiperidine derivatives
WO2002081477A1 (en) * 2001-03-30 2002-10-17 Toray Industries, Inc. 7-substituted morphinane derivatives and medicinal use thereof
GB2471802B (en) * 2006-05-25 2011-02-16 Alpharma Chemical process
MX370608B (es) * 2007-05-01 2019-12-18 Concert Pharmaceuticals Inc Compuestos de morfinano.
US8101757B2 (en) 2007-12-17 2012-01-24 Mallinckrodt Llc Processes for the preparation of normorphinan salts
EP2222677A1 (en) * 2007-12-17 2010-09-01 Mallinckrodt Inc. N-demethylation of n-methyl morphinans
JP2011516464A (ja) 2008-03-31 2011-05-26 サン・ファーマシューティカル・インダストリーズ・リミテッド モルフィナン類似体の改良された調製方法
PL2453895T3 (pl) * 2009-07-16 2018-10-31 Mallinckrodt Llc (+)-morfinany jako antagonisty receptora toll-like 9 i ich zastosowania terapeutyczne
PL2601195T3 (pl) * 2010-08-04 2014-10-31 Mallinckrodt Llc Tandemowy sposób wytwarzania n-alkilomorfinanów
ES2470315T3 (es) * 2010-08-04 2014-06-23 Mallinckrodt Llc N-desmetilaci�n de 6-ceto morfinanos

Also Published As

Publication number Publication date
MX2016005624A (es) 2016-08-19
AU2014348256A1 (en) 2016-05-19
EP3071575A1 (en) 2016-09-28
BR112016010098A2 (pt) 2021-07-06
US9127009B2 (en) 2015-09-08
ES2770591T3 (es) 2020-07-02
MX371334B (es) 2020-01-27
CA2928205A1 (en) 2015-05-21
CA2928205C (en) 2020-04-21
EP3071575A4 (en) 2017-04-19
JP6389252B2 (ja) 2018-09-12
WO2015074049A1 (en) 2015-05-21
JP2016537334A (ja) 2016-12-01
US20150141649A1 (en) 2015-05-21
AU2014348256B2 (en) 2018-06-07
EP3071575B1 (en) 2019-11-13

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