AU2014353235B2 - Rehydration of micronized tecovirimat monohydrate - Google Patents

Rehydration of micronized tecovirimat monohydrate Download PDF

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Publication number
AU2014353235B2
AU2014353235B2 AU2014353235A AU2014353235A AU2014353235B2 AU 2014353235 B2 AU2014353235 B2 AU 2014353235B2 AU 2014353235 A AU2014353235 A AU 2014353235A AU 2014353235 A AU2014353235 A AU 2014353235A AU 2014353235 B2 AU2014353235 B2 AU 2014353235B2
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AU
Australia
Prior art keywords
particles
moisture
monohydrate
micronized
polymorph form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014353235A
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English (en)
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AU2014353235A1 (en
Inventor
Dennis E. Hruby
Steven PRIEBE
Matthew Reeves
N K Peter SAMUEL
Ying Tan
Shantakumar R. Tyavanagimatt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siga Technologies Inc
Original Assignee
Siga Technologies Inc
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Publication date
Application filed by Siga Technologies Inc filed Critical Siga Technologies Inc
Publication of AU2014353235A1 publication Critical patent/AU2014353235A1/en
Application granted granted Critical
Publication of AU2014353235B2 publication Critical patent/AU2014353235B2/en
Priority to AU2019208252A priority Critical patent/AU2019208252B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2014353235A 2013-11-19 2014-11-14 Rehydration of micronized tecovirimat monohydrate Active AU2014353235B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2019208252A AU2019208252B2 (en) 2013-11-19 2019-07-26 Rehydration of micronized tecovirimat monohydrate

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361906119P 2013-11-19 2013-11-19
US61/906,119 2013-11-19
PCT/US2014/065674 WO2015077143A1 (en) 2013-11-19 2014-11-14 Rehydration of micronized tecovirimat monohydrate

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2019208252A Division AU2019208252B2 (en) 2013-11-19 2019-07-26 Rehydration of micronized tecovirimat monohydrate

Publications (2)

Publication Number Publication Date
AU2014353235A1 AU2014353235A1 (en) 2016-04-21
AU2014353235B2 true AU2014353235B2 (en) 2019-05-09

Family

ID=53180052

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2014353235A Active AU2014353235B2 (en) 2013-11-19 2014-11-14 Rehydration of micronized tecovirimat monohydrate
AU2019208252A Active AU2019208252B2 (en) 2013-11-19 2019-07-26 Rehydration of micronized tecovirimat monohydrate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2019208252A Active AU2019208252B2 (en) 2013-11-19 2019-07-26 Rehydration of micronized tecovirimat monohydrate

Country Status (8)

Country Link
US (2) US10406103B2 (enExample)
EP (1) EP3043793B1 (enExample)
JP (1) JP6594303B2 (enExample)
CN (1) CN105636585B (enExample)
AU (2) AU2014353235B2 (enExample)
CA (1) CA2930461C (enExample)
IL (2) IL244731B (enExample)
WO (1) WO2015077143A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020252284A1 (en) * 2019-06-13 2020-12-17 Imbucanna, Inc Compressible cannabinoid pharmaceutical composition

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080004452A1 (en) * 2003-06-20 2008-01-03 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
WO2008079159A2 (en) * 2004-06-18 2008-07-03 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
WO2008130348A1 (en) * 2007-04-23 2008-10-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
CN101445478A (zh) * 2008-08-22 2009-06-03 中国人民解放军军事医学科学院生物工程研究所 含一个结晶水的化合物st-246及其晶体与制备方法
US20110236434A1 (en) * 2010-03-23 2011-09-29 Siga Technologies, Inc. Polymorphic Forms of ST-246 and Methods of Preparation
WO2012018810A1 (en) * 2010-08-05 2012-02-09 Siga Technologies, Inc. St-246 liquid formulations and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10232113A1 (de) * 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
UA97349C2 (uk) * 2005-09-08 2012-02-10 Х. Луннбэк А/С Стійкі тверді склади сертиндолу
JP2011041888A (ja) * 2009-08-20 2011-03-03 Nippon Soda Co Ltd ジェットミル粉砕条件の最適化方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080004452A1 (en) * 2003-06-20 2008-01-03 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
WO2008079159A2 (en) * 2004-06-18 2008-07-03 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
WO2008130348A1 (en) * 2007-04-23 2008-10-30 Siga Technologies, Inc. Chemicals, compositions, and methods for treatment and prevention of orthopoxvirus infections and associated diseases
CN101445478A (zh) * 2008-08-22 2009-06-03 中国人民解放军军事医学科学院生物工程研究所 含一个结晶水的化合物st-246及其晶体与制备方法
US20110236434A1 (en) * 2010-03-23 2011-09-29 Siga Technologies, Inc. Polymorphic Forms of ST-246 and Methods of Preparation
WO2012018810A1 (en) * 2010-08-05 2012-02-09 Siga Technologies, Inc. St-246 liquid formulations and methods

Also Published As

Publication number Publication date
IL282098A (en) 2021-05-31
CN105636585B (zh) 2020-02-07
EP3043793A1 (en) 2016-07-20
JP2016537318A (ja) 2016-12-01
EP3043793B1 (en) 2021-01-06
CN105636585A (zh) 2016-06-01
CA2930461C (en) 2022-08-16
AU2014353235A1 (en) 2016-04-21
JP6594303B2 (ja) 2019-10-23
CA2930461A1 (en) 2015-05-28
IL282098B1 (en) 2023-01-01
AU2019208252B2 (en) 2020-03-19
WO2015077143A1 (en) 2015-05-28
US10716759B2 (en) 2020-07-21
IL244731A0 (en) 2016-04-21
US10406103B2 (en) 2019-09-10
US20160235676A1 (en) 2016-08-18
IL244731B (en) 2021-05-31
IL282098B2 (en) 2023-05-01
EP3043793A4 (en) 2017-05-10
US20190380966A1 (en) 2019-12-19
AU2019208252A1 (en) 2019-08-15

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