IL241452B - Combined treatment of 7 - benzyl - 10 - (2-methylbenzyl) - 2, 6, 7, 8, 9, 10 - hexahydroimidazo [2-1-a] -pyrido [3, 4 -d] pyrimidine - 5 (h3) -potency - Google Patents
Combined treatment of 7 - benzyl - 10 - (2-methylbenzyl) - 2, 6, 7, 8, 9, 10 - hexahydroimidazo [2-1-a] -pyrido [3, 4 -d] pyrimidine - 5 (h3) -potencyInfo
- Publication number
- IL241452B IL241452B IL241452A IL24145215A IL241452B IL 241452 B IL241452 B IL 241452B IL 241452 A IL241452 A IL 241452A IL 24145215 A IL24145215 A IL 24145215A IL 241452 B IL241452 B IL 241452B
- Authority
- IL
- Israel
- Prior art keywords
- hexahydroimidazo
- pyrido
- methylbenzyl
- pyrimidin
- benzyl
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- RSAQARAFWMUYLL-UHFFFAOYSA-N tic-10 Chemical compound CC1=CC=CC=C1CN1C(CCN(CC=2C=CC=CC=2)C2)=C2C(=O)N2CCN=C21 RSAQARAFWMUYLL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779828P | 2013-03-13 | 2013-03-13 | |
| US201361904718P | 2013-11-15 | 2013-11-15 | |
| PCT/US2014/025885 WO2014160130A1 (en) | 2013-03-13 | 2014-03-13 | Combination therapy with 7-benzyl-10-(2-methylbenzyl)-2,6,7,8,9,10-hexahydroimidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3h)-one |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL241452A0 IL241452A0 (en) | 2015-11-30 |
| IL241452B true IL241452B (en) | 2020-07-30 |
Family
ID=51527915
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL241452A IL241452B (en) | 2013-03-13 | 2015-09-10 | Combined treatment of 7 - benzyl - 10 - (2-methylbenzyl) - 2, 6, 7, 8, 9, 10 - hexahydroimidazo [2-1-a] -pyrido [3, 4 -d] pyrimidine - 5 (h3) -potency |
| IL275623A IL275623A (en) | 2013-03-13 | 2020-06-23 | Combined treatment of 7-benzyl-10-(2-methylbenzyl)-2, 6, 7, 8, 9, 10-hexahydroimidazo-[A-1-2]pyrido[4,3-D]pyrimidine - 5 (3H) -potency |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL275623A IL275623A (en) | 2013-03-13 | 2020-06-23 | Combined treatment of 7-benzyl-10-(2-methylbenzyl)-2, 6, 7, 8, 9, 10-hexahydroimidazo-[A-1-2]pyrido[4,3-D]pyrimidine - 5 (3H) -potency |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US9265765B2 (enExample) |
| EP (2) | EP3572083A1 (enExample) |
| JP (3) | JP6446025B2 (enExample) |
| KR (2) | KR20220123335A (enExample) |
| CN (2) | CN105530937A (enExample) |
| AU (3) | AU2014244117B2 (enExample) |
| BR (1) | BR112015023256A2 (enExample) |
| CA (2) | CA3204801A1 (enExample) |
| CY (1) | CY1121735T1 (enExample) |
| DK (1) | DK2968294T3 (enExample) |
| EA (1) | EA037937B1 (enExample) |
| ES (1) | ES2734568T3 (enExample) |
| HR (1) | HRP20191181T1 (enExample) |
| HU (1) | HUE044238T2 (enExample) |
| IL (2) | IL241452B (enExample) |
| LT (1) | LT2968294T (enExample) |
| ME (1) | ME03470B (enExample) |
| MX (2) | MX2015012636A (enExample) |
| NZ (2) | NZ711948A (enExample) |
| PL (1) | PL2968294T3 (enExample) |
| PT (1) | PT2968294T (enExample) |
| RS (1) | RS59013B1 (enExample) |
| SG (2) | SG10201808496VA (enExample) |
| SI (1) | SI2968294T1 (enExample) |
| SM (1) | SMT201900384T1 (enExample) |
| WO (1) | WO2014160130A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SMT202000272T1 (it) | 2011-04-29 | 2020-07-08 | Penn State Res Found | Induzione del gene trail da parte di cellule normali e tumorali mediante una piccola molecola come terapia anticancro |
| KR20220123335A (ko) | 2013-03-13 | 2022-09-06 | 온코슈틱스 인코포레이티드 | 7-벤질-10-(2-메틸벤질)-2,6,7,8,9,10-헥사하이드로이미다조[1,2-a]피리도[4,3-d]피리미딘-5(3h)-온과의 조합 치료요법 |
| US9376437B2 (en) | 2013-03-13 | 2016-06-28 | Oncoceutics, Inc | 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, salts thereof and methods of using the same in combination therapy |
| PT2970473T (pt) | 2013-03-14 | 2017-10-26 | Bristol Myers Squibb Co | Combinação de agonista de dr5 e antagonista anti-pd-1 e métodos de utilização |
| ES2724331T3 (es) * | 2013-11-15 | 2019-09-10 | Oncoceutics Inc | 7-Bencil-4-(2-metilbencil)-2,4,6,7,8,9-hexahidroimidazo[1,2-a]pirido[3,4-e]pirimidin-5(1H)-ona, sales de la misma y procedimientos de uso |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| ES3040431T3 (en) | 2014-03-12 | 2025-10-31 | Yeda Res & Dev | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns |
| US9394365B1 (en) | 2014-03-12 | 2016-07-19 | Yeda Research And Development Co., Ltd | Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease |
| ES2999685T3 (en) * | 2014-03-31 | 2025-02-26 | Scripps Research Inst | Pharmacophore for trail induction |
| MD3805222T2 (ro) * | 2015-01-30 | 2025-04-30 | Oncoceutics Inc | Derivați de 7-benzil-4-(2-metilbenzil)-2,4,6,7,8,9-hexahidroimidazo[1,2-a]pirido[3,4-e]pirimidin-5(1H)-ona, sărurile acestora și utilizarea acestora în terapie |
| CN104860948B (zh) * | 2015-05-15 | 2017-09-26 | 南京盖特医药技术有限公司 | 咪唑并嘧啶酮类化合物及其制备方法和应用 |
| EA201890512A1 (ru) * | 2015-08-17 | 2018-09-28 | Кура Онколоджи, Инк. | Способы лечения пациентов со злокачественными опухолями с использованием ингибиторов фарнезилтрансферазы |
| KR20170037260A (ko) | 2015-09-25 | 2017-04-04 | 현대자동차주식회사 | 차량용 배터리 시스템 및 그 제어 방법 |
| DK3408298T3 (en) | 2016-01-29 | 2025-03-03 | Oncoceutics Inc | G protein-coupled receptor (gpcr) modulation by imipridones |
| MA45280B1 (fr) | 2016-03-02 | 2021-08-31 | Eisai R&D Man Co Ltd | Conjugués anticorps-médicament à base d'éribuline et leurs procédés d'utilisation |
| KR20170110520A (ko) * | 2016-03-23 | 2017-10-11 | 고려대학교 산학협력단 | mTOR 억제제 및 N-아세틸시스테인을 포함하는 간섬유화 억제용 조성물 |
| EP3439642A4 (en) * | 2016-04-06 | 2019-11-13 | Noxopharm Limited | IMPROVEMENTS IN RADIOTHERAPY |
| AU2017247008B2 (en) | 2016-04-06 | 2022-04-07 | Noxopharm Limited | Isoflavonoid composition with improved pharmacokinetics |
| CN109789144B (zh) * | 2016-08-12 | 2022-04-15 | 马德拉医疗公司 | 蛋白激酶调节剂 |
| RS61745B1 (sr) | 2016-11-03 | 2021-05-31 | Kura Oncology Inc | Inhibitori farneziltransferaze za upotrebu u tretiranju kancera |
| EP3565548A4 (en) | 2017-01-04 | 2020-10-14 | The Board of Trustees of the Leland Stanford Junior University | TARGET GENES IN MYC-INDUCED NEOPLASIA |
| CN110291089B (zh) | 2017-01-17 | 2022-05-27 | 海帕瑞吉尼克斯股份有限公司 | 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂 |
| US10172862B2 (en) | 2017-01-30 | 2019-01-08 | Oncoceutics, Inc. | Imipridones for gliomas |
| IT201800004082A1 (it) * | 2018-03-29 | 2019-09-29 | Berlin Chemie Ag | Composizioni farmaceutiche antitumorali per terapia combinata |
| US20200046703A1 (en) * | 2018-08-09 | 2020-02-13 | Asymmetric Therapeutics, Llc | Compositions and methods for treatment of the side-effects associated with administration of therapeutic agents |
| KR20210108414A (ko) | 2018-12-25 | 2021-09-02 | 솔-겔 테크놀로지스 리미티드 | Egfr 억제제를 포함하는 조성물에 의한 피부 장애 치료 |
| WO2020147842A1 (zh) * | 2019-01-18 | 2020-07-23 | 南京明德新药研发有限公司 | 吡啶并嘧啶类化合物在制备治疗鼻咽癌药物中的应用 |
| EP3725370A1 (en) | 2019-04-19 | 2020-10-21 | ImmunoBrain Checkpoint, Inc. | Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease |
| CA3159860C (en) * | 2019-11-28 | 2025-05-20 | Inxmed (Nanjing) Co., Ltd. | USE OF BI853520 IN CANCER TREATMENT |
| EP4087840A4 (en) | 2020-01-10 | 2024-01-10 | Immuneering Corporation | Mek inhibitors and therapeutic uses thereof |
| EP4125870A1 (en) | 2020-03-30 | 2023-02-08 | Noxopharm Limited | Methods for the treatment of inflammation associated with infection |
| CN117599041B (zh) * | 2024-01-22 | 2024-05-03 | 中国人民解放军军事科学院军事医学研究院 | 去氢雌马酚及其衍生物作为新型辐射防护剂和细胞保护剂的医药用途 |
| EP4684834A1 (de) | 2024-07-26 | 2026-01-28 | BRIU GmbH | Kristallformen onkologisch wirksamer imipridone und verfahren zu deren herstellung |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2150062A1 (de) * | 1971-10-07 | 1973-04-12 | Boehringer Sohn Ingelheim | Imidazo- eckige klammer auf 1,2-a eckige klammer zu -pyrido- eckige klammer auf 4,3-d eckige klammer zu -pyrimidine, deren saeureadditionssalze und verfahren zu deren herstellung |
| US4642345A (en) | 1980-08-14 | 1987-02-10 | Mead Johnson & Company | 6,7-dihydro-3H-imidazo[1,2-a]-purine-9(4H)-ones |
| US7635690B2 (en) | 1999-01-22 | 2009-12-22 | Emory University | HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine |
| CA2478338A1 (en) | 2002-03-08 | 2003-09-18 | Signal Pharmaceuticals, Inc. | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| WO2006089290A1 (en) | 2005-02-18 | 2006-08-24 | Abraxis Bioscience Inc.. | Combinations and modes of administration of therapeutic agents and combination therapy |
| US20080221135A1 (en) | 2005-05-13 | 2008-09-11 | Bristol-Myers Squibb Company | Combination therapy |
| WO2010033315A1 (en) | 2008-09-22 | 2010-03-25 | Amgen Inc. | Method of treatment |
| NZ593343A (en) | 2008-12-11 | 2013-04-26 | Abraxis Bioscience Llc | Combination cancer treatment conprising Abraxane and an inflamatory inhibitor |
| US9724337B2 (en) | 2009-04-21 | 2017-08-08 | University Of Kentucky Research Foundation | AG-205 for the treatment of breast cancer |
| DE102010014426A1 (de) * | 2010-04-01 | 2011-10-06 | Bayer Schering Pharma Aktiengesellschaft | Verwendung neuer pan-CDK-Inhibitoren zur Behandlung von Tumoren |
| SMT202000272T1 (it) * | 2011-04-29 | 2020-07-08 | Penn State Res Found | Induzione del gene trail da parte di cellule normali e tumorali mediante una piccola molecola come terapia anticancro |
| US8377946B1 (en) | 2011-12-30 | 2013-02-19 | Pharmacyclics, Inc. | Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors |
| KR20220123335A (ko) | 2013-03-13 | 2022-09-06 | 온코슈틱스 인코포레이티드 | 7-벤질-10-(2-메틸벤질)-2,6,7,8,9,10-헥사하이드로이미다조[1,2-a]피리도[4,3-d]피리미딘-5(3h)-온과의 조합 치료요법 |
| ES2999685T3 (en) | 2014-03-31 | 2025-02-26 | Scripps Research Inst | Pharmacophore for trail induction |
-
2014
- 2014-03-13 KR KR1020227029471A patent/KR20220123335A/ko not_active Ceased
- 2014-03-13 LT LTEP14775569.8T patent/LT2968294T/lt unknown
- 2014-03-13 SG SG10201808496VA patent/SG10201808496VA/en unknown
- 2014-03-13 MX MX2015012636A patent/MX2015012636A/es active IP Right Grant
- 2014-03-13 PT PT14775569T patent/PT2968294T/pt unknown
- 2014-03-13 RS RS20190874A patent/RS59013B1/sr unknown
- 2014-03-13 NZ NZ711948A patent/NZ711948A/en unknown
- 2014-03-13 ES ES14775569T patent/ES2734568T3/es active Active
- 2014-03-13 CA CA3204801A patent/CA3204801A1/en active Pending
- 2014-03-13 EP EP19171477.3A patent/EP3572083A1/en not_active Withdrawn
- 2014-03-13 PL PL14775569T patent/PL2968294T3/pl unknown
- 2014-03-13 BR BR112015023256A patent/BR112015023256A2/pt not_active Application Discontinuation
- 2014-03-13 SI SI201431257T patent/SI2968294T1/sl unknown
- 2014-03-13 KR KR1020157028393A patent/KR102438135B1/ko active Active
- 2014-03-13 HU HUE14775569 patent/HUE044238T2/hu unknown
- 2014-03-13 CA CA2905037A patent/CA2905037C/en active Active
- 2014-03-13 ME MEP-2019-197A patent/ME03470B/me unknown
- 2014-03-13 DK DK14775569.8T patent/DK2968294T3/da active
- 2014-03-13 EA EA201591715A patent/EA037937B1/ru unknown
- 2014-03-13 EP EP14775569.8A patent/EP2968294B1/en active Active
- 2014-03-13 CN CN201480022856.7A patent/CN105530937A/zh active Pending
- 2014-03-13 SG SG11201507247WA patent/SG11201507247WA/en unknown
- 2014-03-13 AU AU2014244117A patent/AU2014244117B2/en not_active Ceased
- 2014-03-13 US US14/208,657 patent/US9265765B2/en active Active
- 2014-03-13 CN CN202510107155.3A patent/CN119954807A/zh active Pending
- 2014-03-13 JP JP2016501988A patent/JP6446025B2/ja active Active
- 2014-03-13 HR HRP20191181TT patent/HRP20191181T1/hr unknown
- 2014-03-13 NZ NZ751509A patent/NZ751509A/en active IP Right Revival
- 2014-03-13 SM SM20190384T patent/SMT201900384T1/it unknown
- 2014-03-13 WO PCT/US2014/025885 patent/WO2014160130A1/en not_active Ceased
-
2015
- 2015-09-10 IL IL241452A patent/IL241452B/en active IP Right Grant
- 2015-09-11 MX MX2019013643A patent/MX2019013643A/es unknown
-
2018
- 2018-06-22 JP JP2018119005A patent/JP2018184411A/ja active Pending
-
2019
- 2019-03-19 AU AU2019201896A patent/AU2019201896A1/en not_active Abandoned
- 2019-07-01 CY CY20191100687T patent/CY1121735T1/el unknown
-
2020
- 2020-06-23 IL IL275623A patent/IL275623A/en unknown
- 2020-07-01 JP JP2020114024A patent/JP2020172510A/ja active Pending
- 2020-09-14 AU AU2020233606A patent/AU2020233606A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL275623A (en) | Combined treatment of 7-benzyl-10-(2-methylbenzyl)-2, 6, 7, 8, 9, 10-hexahydroimidazo-[A-1-2]pyrido[4,3-D]pyrimidine - 5 (3H) -potency | |
| IL288525A (en) | 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo-[1,2-a] pyrido [3,4-e] pyrimidine-5(1h)-one, analogs and salts thereof, and methods of use for therapy | |
| IL288674A (en) | 7-Benzyl-4-(2-methylbenzyl)-2, 4, 6, 7, 8, 9-hexahydroimidazo [1,2-a]pyrido[3,4-e]pyrimidine-5(1h)one, its salts and methods Use | |
| IL243092B (en) | New triazolo[d–4,5]pyrimidine histories | |
| ZA201507151B (en) | Antiviral indolo[2,3-b]quinoxaline |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |