IL236423A - A super-saturated solution of acetaminophen for injection into the spine - Google Patents

A super-saturated solution of acetaminophen for injection into the spine

Info

Publication number
IL236423A
IL236423A IL236423A IL23642314A IL236423A IL 236423 A IL236423 A IL 236423A IL 236423 A IL236423 A IL 236423A IL 23642314 A IL23642314 A IL 23642314A IL 236423 A IL236423 A IL 236423A
Authority
IL
Israel
Prior art keywords
spinal administration
acetaminophen solution
injectable
supersaturated acetaminophen
injectable supersaturated
Prior art date
Application number
IL236423A
Other languages
English (en)
Hebrew (he)
Other versions
IL236423A0 (en
Inventor
Mitidieri Augusto
Donati Elisabetta
Caronzolo Nicola
Original Assignee
Sintetica S A
Mitidieri Augusto
Donati Elisabetta
Caronzolo Nicola
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46690603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL236423(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sintetica S A, Mitidieri Augusto, Donati Elisabetta, Caronzolo Nicola filed Critical Sintetica S A
Publication of IL236423A0 publication Critical patent/IL236423A0/en
Publication of IL236423A publication Critical patent/IL236423A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL236423A 2012-06-29 2014-12-23 A super-saturated solution of acetaminophen for injection into the spine IL236423A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001154A ITMI20121154A1 (it) 2012-06-29 2012-06-29 Soluzione iniettabile di acetaminofene per la somministrazione spinale
PCT/IB2013/055277 WO2014002042A1 (en) 2012-06-29 2013-06-27 Injectable supersaturated acetaminophen solution for spinal administration

Publications (2)

Publication Number Publication Date
IL236423A0 IL236423A0 (en) 2015-02-26
IL236423A true IL236423A (en) 2017-07-31

Family

ID=46690603

Family Applications (1)

Application Number Title Priority Date Filing Date
IL236423A IL236423A (en) 2012-06-29 2014-12-23 A super-saturated solution of acetaminophen for injection into the spine

Country Status (44)

Country Link
US (2) US11344517B2 (enExample)
EP (1) EP2874602B1 (enExample)
JP (1) JP5876620B2 (enExample)
KR (1) KR102118227B1 (enExample)
CN (1) CN104487051B (enExample)
AP (1) AP2014008152A0 (enExample)
AR (1) AR091633A1 (enExample)
AU (1) AU2013282753B2 (enExample)
BR (1) BR112014032818B1 (enExample)
CA (1) CA2876801C (enExample)
CL (1) CL2014003536A1 (enExample)
CO (1) CO7240357A2 (enExample)
CR (1) CR20150036A (enExample)
CU (1) CU20140150A7 (enExample)
CY (1) CY1117691T1 (enExample)
DK (1) DK2874602T3 (enExample)
DO (1) DOP2014000302A (enExample)
EA (1) EA028909B1 (enExample)
EC (1) ECSP15000500A (enExample)
ES (1) ES2578012T3 (enExample)
GE (1) GEP201706689B (enExample)
HR (1) HRP20160706T1 (enExample)
HU (1) HUE029431T2 (enExample)
IL (1) IL236423A (enExample)
IT (1) ITMI20121154A1 (enExample)
MA (1) MA37811B1 (enExample)
MD (1) MD4537C1 (enExample)
ME (1) ME02431B (enExample)
MX (1) MX369264B (enExample)
MY (1) MY169251A (enExample)
NI (1) NI201400147A (enExample)
NZ (1) NZ703829A (enExample)
PE (1) PE20150331A1 (enExample)
PH (1) PH12015500178B1 (enExample)
PL (1) PL2874602T3 (enExample)
PT (1) PT2874602T (enExample)
RS (1) RS54844B1 (enExample)
SG (2) SG11201408479WA (enExample)
SI (1) SI2874602T1 (enExample)
SM (1) SMT201600248B (enExample)
TN (1) TN2014000526A1 (enExample)
UA (1) UA117101C2 (enExample)
WO (1) WO2014002042A1 (enExample)
ZA (1) ZA201409478B (enExample)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0162115B1 (ko) * 1993-04-14 1998-11-16 노자키 지로 용존산소 감소장치
US6171298B1 (en) * 1996-05-03 2001-01-09 Situs Corporation Intravesical infuser
FR2751875B1 (fr) 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
FR2809619B1 (fr) 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
DE10112325A1 (de) * 2001-03-13 2002-10-02 Fresenius Kabi De Gmbh Lagerstabile Fertiginfusionslösungen des Paracetamols
WO2003051398A1 (en) * 2001-12-18 2003-06-26 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Parenteral composition of paracetamol
FR2851164B1 (fr) 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
DE102005037653A1 (de) * 2005-08-05 2007-02-15 Theraselect Gmbh Stabile, flüssige Formulierung von Paracetamol
AU2006346318B2 (en) * 2006-07-18 2011-02-10 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
CN101015542A (zh) * 2007-02-13 2007-08-15 天津生机集团有限公司 家畜用复方对乙酰氨基酚注射液及其制备方法
MD3528G2 (ro) * 2007-09-28 2008-11-30 Сергей ШАНДРУ Metodă de anestezie spinală continuă la pacienţii în etate
CA2705733C (en) * 2007-11-13 2015-02-03 Cadence Pharmaceuticals Reduced dose intravenous acetaminophen
WO2009098716A2 (en) 2008-01-17 2009-08-13 Aptuit Laurus Private Limited Stable pharmaceutical aqueous compositions
WO2009143558A1 (en) * 2008-05-26 2009-12-03 Silphion Pty Limited Injectable formulations
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
JP2013006770A (ja) * 2009-10-09 2013-01-10 Ssp Co Ltd アセトアミノフェン含有経口液剤
PH12012502444A1 (en) * 2010-06-30 2013-02-11 Troikaa Pharmaceuticals Ltd Pharmaceutical compositions comprising paracetamol and process for preparing the same

Also Published As

Publication number Publication date
PE20150331A1 (es) 2015-03-07
PT2874602T (pt) 2016-07-13
MA37811B1 (fr) 2017-07-31
MX2014015402A (es) 2015-06-17
CU20140150A7 (es) 2015-10-27
ITMI20121154A1 (it) 2013-12-30
ES2578012T3 (es) 2016-07-20
AP2014008152A0 (en) 2014-12-31
MD4537C1 (ro) 2018-07-31
NI201400147A (es) 2015-04-13
US20150148379A1 (en) 2015-05-28
US11344517B2 (en) 2022-05-31
EP2874602B1 (en) 2016-03-30
JP5876620B2 (ja) 2016-03-02
CN104487051B (zh) 2017-12-12
DOP2014000302A (es) 2015-03-15
HUE029431T2 (en) 2017-03-28
DK2874602T3 (en) 2016-07-04
PL2874602T3 (pl) 2016-10-31
SI2874602T1 (sl) 2016-09-30
CN104487051A (zh) 2015-04-01
KR20150027160A (ko) 2015-03-11
MX369264B (es) 2019-11-04
ME02431B (me) 2016-09-20
SMT201600248B (it) 2016-08-31
CL2014003536A1 (es) 2015-05-08
AU2013282753A1 (en) 2015-02-05
SG11201408479WA (en) 2015-01-29
NZ703829A (en) 2016-06-24
MA37811A1 (fr) 2016-10-31
EP2874602A1 (en) 2015-05-27
AR091633A1 (es) 2015-02-18
CA2876801C (en) 2020-11-03
CY1117691T1 (el) 2017-05-17
ECSP15000500A (es) 2015-11-30
MD4537B1 (ro) 2017-12-31
TN2014000526A1 (en) 2016-03-30
BR112014032818A2 (pt) 2017-06-27
JP2015522004A (ja) 2015-08-03
GEP201706689B (en) 2017-06-26
CR20150036A (es) 2015-03-13
BR112014032818B1 (pt) 2022-06-14
CA2876801A1 (en) 2014-01-03
EA028909B1 (ru) 2018-01-31
ZA201409478B (en) 2016-01-27
IL236423A0 (en) 2015-02-26
RS54844B1 (sr) 2016-10-31
EA201500065A1 (ru) 2015-10-30
US20160128955A1 (en) 2016-05-12
UA117101C2 (uk) 2018-06-25
WO2014002042A1 (en) 2014-01-03
CO7240357A2 (es) 2015-04-17
MD20140138A2 (ro) 2015-06-30
SG10201704482YA (en) 2017-07-28
KR102118227B1 (ko) 2020-06-03
HRP20160706T1 (hr) 2016-08-12
AU2013282753B2 (en) 2017-03-02
PH12015500178A1 (en) 2015-04-06
MY169251A (en) 2019-03-19
PH12015500178B1 (en) 2021-08-04

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