IL233620A0 - Sustained-release biodegradable or chewable microspheres or microparticles suspended in an injectable drug formulation produce a solidified precipitate - Google Patents
Sustained-release biodegradable or chewable microspheres or microparticles suspended in an injectable drug formulation produce a solidified precipitateInfo
- Publication number
- IL233620A0 IL233620A0 IL233620A IL23362014A IL233620A0 IL 233620 A0 IL233620 A0 IL 233620A0 IL 233620 A IL233620 A IL 233620A IL 23362014 A IL23362014 A IL 23362014A IL 233620 A0 IL233620 A0 IL 233620A0
- Authority
- IL
- Israel
- Prior art keywords
- drug formulation
- injectable drug
- time released
- microparticles suspended
- bioerodible microspheres
- Prior art date
Links
- 239000013583 drug formulation Substances 0.000 title 1
- 239000011859 microparticle Substances 0.000 title 1
- 239000004005 microsphere Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dispersion Chemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261589681P | 2012-01-23 | 2012-01-23 | |
| PCT/US2013/022466 WO2013112434A1 (en) | 2012-01-23 | 2013-01-22 | Time released biodegradable or bioerodible microspheres or microparticles suspended in a solidifying depot-forming injectable drug formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL233620A0 true IL233620A0 (en) | 2014-08-31 |
Family
ID=47630595
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL233620A IL233620A0 (en) | 2012-01-23 | 2014-07-13 | Sustained-release biodegradable or chewable microspheres or microparticles suspended in an injectable drug formulation produce a solidified precipitate |
| IL265620A IL265620B (en) | 2012-01-23 | 2019-03-26 | Sustained-release biodegradable or chewable microspheres or microparticles suspended in an injectable drug formulation produce a solidified precipitate |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL265620A IL265620B (en) | 2012-01-23 | 2019-03-26 | Sustained-release biodegradable or chewable microspheres or microparticles suspended in an injectable drug formulation produce a solidified precipitate |
Country Status (17)
| Country | Link |
|---|---|
| US (5) | US20130189369A1 (enExample) |
| EP (1) | EP2806853B1 (enExample) |
| JP (1) | JP6282231B2 (enExample) |
| KR (5) | KR102183727B1 (enExample) |
| CN (1) | CN104136006B (enExample) |
| AU (3) | AU2013212583A1 (enExample) |
| BR (1) | BR112014017969A8 (enExample) |
| CA (1) | CA2861348C (enExample) |
| DK (1) | DK2806853T3 (enExample) |
| ES (1) | ES2821526T3 (enExample) |
| HU (1) | HUE050904T2 (enExample) |
| IL (2) | IL233620A0 (enExample) |
| MX (1) | MX364864B (enExample) |
| NZ (1) | NZ627368A (enExample) |
| RU (1) | RU2672596C2 (enExample) |
| WO (1) | WO2013112434A1 (enExample) |
| ZA (1) | ZA201405091B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6282231B2 (ja) * | 2012-01-23 | 2018-02-21 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 固化するデポー形成の注入可能な薬物製剤に懸濁される持続放出された生分解性または生体侵食性微小球または微小粒子 |
| US20170112936A1 (en) * | 2014-05-23 | 2017-04-27 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions comprising gels and methods for fabricating thereof |
| US20150335704A1 (en) * | 2014-05-23 | 2015-11-26 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions comprising gels and methods for fabricating thereof |
| CN104306330A (zh) * | 2014-09-24 | 2015-01-28 | 万特制药(海南)有限公司 | 一种盐酸美金刚缓释混悬液及其制备方法 |
| US20170079985A1 (en) | 2015-09-21 | 2017-03-23 | Teva Pharmaceuticals International Gmbh | Sustained release olanzapine formulations |
| CN108367079B (zh) | 2015-11-12 | 2022-11-22 | 灰色视觉公司 | 用于治疗的聚集性微粒 |
| EP3478285A4 (en) * | 2016-06-30 | 2020-07-22 | Durect Corporation | DEPOSIT FORMULATIONS |
| US10682340B2 (en) | 2016-06-30 | 2020-06-16 | Durect Corporation | Depot formulations |
| JP2020511483A (ja) | 2017-03-20 | 2020-04-16 | テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーＴｅｖａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ ＧｍｂＨ | 徐放性オランザピン製剤 |
| EP3621654A4 (en) | 2017-05-10 | 2021-02-17 | Graybug Vision, Inc. | PROLONGED-RELEASE MICROPARTICLES AND SUSPENSIONS OF THESE INTENDED FOR MEDICAL THERAPY |
| EP3651800B1 (en) * | 2017-07-11 | 2024-04-10 | Sustained Nano Systems LLC | Hypercompressed pharmaceutical formulations |
| CN107595765A (zh) * | 2017-09-22 | 2018-01-19 | 沈阳兴齐眼药股份有限公司 | 一种眼用缓释药物递送系统及其制备方法 |
| GB2586975B (en) * | 2019-09-09 | 2024-03-06 | Roemex Ltd | Device and method for use with subsea pipelines |
| EP4277661A1 (en) | 2021-01-18 | 2023-11-22 | Anton Frenkel | Pharmaceutical dosage form |
| WO2022198167A1 (en) * | 2021-03-15 | 2022-09-22 | Oakwood Laboratories, Llc | Microsphere formulations comprising naltrexone and methods for making and using the same |
| WO2023281406A1 (en) | 2021-07-06 | 2023-01-12 | Mark Hasleton | Treatment of serotonin reuptake inhibitor withdrawal syndrome |
| CN116869914A (zh) * | 2023-05-30 | 2023-10-13 | 庄秉谚 | 无针注射系统的投递物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
| WO1995027481A1 (en) * | 1994-04-08 | 1995-10-19 | Atrix Laboratories, Inc. | Liquid delivery compositions |
| AU739469B2 (en) * | 1996-12-20 | 2001-10-11 | Alza Corporation | Gel composition and methods |
| US6589549B2 (en) * | 2000-04-27 | 2003-07-08 | Macromed, Incorporated | Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles |
| GB0122318D0 (en) * | 2001-09-14 | 2001-11-07 | Novartis Ag | Organic compounds |
| US20070196415A1 (en) * | 2002-11-14 | 2007-08-23 | Guohua Chen | Depot compositions with multiple drug release rate controls and uses thereof |
| CN1314452C (zh) * | 2002-04-22 | 2007-05-09 | 沈阳药科大学 | 具有适宜相转变温度的眼用原位凝胶制剂 |
| EP1568359A4 (en) * | 2002-12-04 | 2011-05-18 | Santen Pharmaceutical Co Ltd | DRUG DELIVERY SYSTEM HAVING SUB-CONJUNCTIVAL DEPOSIT |
| US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
| US20060182781A1 (en) * | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Methods for treating ocular conditions with cyclic lipid contraining microparticles |
| US7893040B2 (en) * | 2005-07-22 | 2011-02-22 | Oculis Ehf | Cyclodextrin nanotechnology for ophthalmic drug delivery |
| US20070202186A1 (en) * | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| AU2008268222B2 (en) * | 2007-06-25 | 2013-12-12 | Otsuka Pharmaceutical Co., Ltd. | Microspheres having core/shell structure |
| EP2482804A1 (en) * | 2009-10-01 | 2012-08-08 | Evonik Degussa Corporation | Microparticle compositions and methods for treating age-related macular degeneration |
| CN101816627B (zh) * | 2010-04-16 | 2012-03-07 | 浙江大学 | 一种协同治疗型多物质缓释滴眼剂及制备方法 |
| CN102100663B (zh) * | 2011-01-14 | 2013-04-17 | 华南理工大学 | 一种pH敏感型原位凝胶纳米缓释眼药水的制备方法 |
| JP6282231B2 (ja) * | 2012-01-23 | 2018-02-21 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 固化するデポー形成の注入可能な薬物製剤に懸濁される持続放出された生分解性または生体侵食性微小球または微小粒子 |
-
2013
- 2013-01-22 JP JP2014553507A patent/JP6282231B2/ja not_active Expired - Fee Related
- 2013-01-22 EP EP13702182.0A patent/EP2806853B1/en active Active
- 2013-01-22 ES ES13702182T patent/ES2821526T3/es active Active
- 2013-01-22 KR KR1020207016713A patent/KR102183727B1/ko not_active Expired - Fee Related
- 2013-01-22 KR KR1020147023407A patent/KR20140114892A/ko not_active Ceased
- 2013-01-22 US US13/746,592 patent/US20130189369A1/en not_active Abandoned
- 2013-01-22 NZ NZ627368A patent/NZ627368A/en not_active IP Right Cessation
- 2013-01-22 CN CN201380010884.2A patent/CN104136006B/zh active Active
- 2013-01-22 CA CA2861348A patent/CA2861348C/en active Active
- 2013-01-22 MX MX2014008857A patent/MX364864B/es active IP Right Grant
- 2013-01-22 DK DK13702182.0T patent/DK2806853T3/da active
- 2013-01-22 KR KR1020207033455A patent/KR20200133286A/ko not_active Ceased
- 2013-01-22 KR KR1020237021933A patent/KR20230104761A/ko not_active Ceased
- 2013-01-22 RU RU2014134420A patent/RU2672596C2/ru active
- 2013-01-22 BR BR112014017969A patent/BR112014017969A8/pt not_active Application Discontinuation
- 2013-01-22 WO PCT/US2013/022466 patent/WO2013112434A1/en not_active Ceased
- 2013-01-22 KR KR1020227010024A patent/KR20220044379A/ko not_active Ceased
- 2013-01-22 HU HUE13702182A patent/HUE050904T2/hu unknown
- 2013-01-22 AU AU2013212583A patent/AU2013212583A1/en not_active Abandoned
-
2014
- 2014-07-11 ZA ZA2014/05091A patent/ZA201405091B/en unknown
- 2014-07-13 IL IL233620A patent/IL233620A0/en active IP Right Grant
-
2017
- 2017-11-09 AU AU2017258895A patent/AU2017258895B2/en not_active Ceased
-
2019
- 2019-03-26 IL IL265620A patent/IL265620B/en unknown
- 2019-07-10 AU AU2019204957A patent/AU2019204957A1/en not_active Abandoned
- 2019-12-19 US US16/720,892 patent/US20200297650A1/en not_active Abandoned
-
2022
- 2022-12-27 US US18/146,921 patent/US20230390212A1/en not_active Abandoned
-
2023
- 2023-08-21 US US18/453,123 patent/US20240226022A1/en not_active Abandoned
-
2024
- 2024-04-01 US US18/623,822 patent/US20240423922A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL265620B (en) | Sustained-release biodegradable or chewable microspheres or microparticles suspended in an injectable drug formulation produce a solidified precipitate | |
| IL305990B2 (en) | A long-acting injectable preparation containing polymeric microspheres of modified compressed gamma-carboline heterocyclic compounds or a sustained-release pharmaceutical preparation containing these compounds for use in the treatment of bipolar I and/or bipolar II disorders | |
| SG11201406799XA (en) | A delayed release drug formulation | |
| EP2831842A4 (en) | PARTICIPATORY SURVEILLANCE BASED ON LOCALIZATION TRIGGERED BY EVENTS | |
| PL2701687T3 (pl) | Kompozycja mikrosfery rysperydonu o przedłużonym uwalnianiu | |
| IL240148A0 (en) | Biodegradable and clinically compatible nanoparticles as drug delivery carriers | |
| ZA201600630B (en) | A delayed release drug formulation | |
| PL2987484T3 (pl) | Kompozycja farmaceutyczna mikrosfery o przedłużonym uwalnianiu gosereliny | |
| ZA201407675B (en) | A delayed release drug formulation | |
| EP2897597A4 (en) | BIODEGRADABLE MULTI-LAYER MICROPARTICLES FOR PROLONGED RELEASE OF THERAPEUTIC AGENTS | |
| TWI559972B (en) | Microparticle and addition agent | |
| GB201300437D0 (en) | Injectable Active Ingredient Release Compositions and Methods for Their Production and Use | |
| GB201205083D0 (en) | Gravity anchor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |