PL2987484T3 - Kompozycja farmaceutyczna mikrosfery o przedłużonym uwalnianiu gosereliny - Google Patents
Kompozycja farmaceutyczna mikrosfery o przedłużonym uwalnianiu goserelinyInfo
- Publication number
- PL2987484T3 PL2987484T3 PL14785916T PL14785916T PL2987484T3 PL 2987484 T3 PL2987484 T3 PL 2987484T3 PL 14785916 T PL14785916 T PL 14785916T PL 14785916 T PL14785916 T PL 14785916T PL 2987484 T3 PL2987484 T3 PL 2987484T3
- Authority
- PL
- Poland
- Prior art keywords
- pharmaceutical composition
- sustained release
- release microsphere
- goserelin
- microsphere pharmaceutical
- Prior art date
Links
- BLCLNMBMMGCOAS-URPVMXJPSA-N Goserelin Chemical compound C([C@@H](C(=O)N[C@H](COC(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1[C@@H](CCC1)C(=O)NNC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 BLCLNMBMMGCOAS-URPVMXJPSA-N 0.000 title 1
- 108010069236 Goserelin Proteins 0.000 title 1
- 229960002913 goserelin Drugs 0.000 title 1
- 239000004005 microsphere Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310136505 | 2013-04-18 | ||
| EP14785916.9A EP2987484B1 (en) | 2013-04-18 | 2014-04-16 | Goserelin sustained release microsphere pharmaceutical composition |
| PCT/CN2014/075441 WO2014169816A1 (zh) | 2013-04-18 | 2014-04-16 | 戈舍瑞林缓释微球药物组合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2987484T3 true PL2987484T3 (pl) | 2019-07-31 |
Family
ID=51704550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14785916T PL2987484T3 (pl) | 2013-04-18 | 2014-04-16 | Kompozycja farmaceutyczna mikrosfery o przedłużonym uwalnianiu gosereliny |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20160022584A1 (pl) |
| EP (1) | EP2987484B1 (pl) |
| JP (1) | JP6151848B2 (pl) |
| CN (1) | CN104107434B (pl) |
| ES (1) | ES2716384T3 (pl) |
| PL (1) | PL2987484T3 (pl) |
| RU (1) | RU2694901C2 (pl) |
| WO (1) | WO2014169816A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201805191D0 (en) * | 2018-03-29 | 2018-05-16 | Camurus Ab | Compositions |
| KR20200051916A (ko) * | 2018-11-05 | 2020-05-14 | 주식회사 메디포럼제약 | 고세렐린을 포함하는 실리카 하이드로겔 조성물 |
| JP2023151957A (ja) * | 2022-04-01 | 2023-10-16 | 理研ビタミン株式会社 | 薬物含有粒子の製造方法 |
| CN119139240B (zh) * | 2024-10-08 | 2026-03-03 | 北京博恩特药业有限公司 | 一种戈舍瑞林微球的制备方法及其产品 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| AR012448A1 (es) * | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
| IE980115A1 (en) | 1998-02-16 | 2000-02-09 | Biovail Internat Ltd | Solubilizing delivery systems and method of manufacture |
| AU3323902A (en) * | 2000-12-13 | 2002-06-24 | Merckle Gmbh | Microparticles with an improved release profile and method for the production thereof |
| WO2006123361A2 (en) * | 2005-03-01 | 2006-11-23 | Sun Pharmaceutical Industries Limited | Microspheres containing goserelin or a pharmaceutically acceptable salt thereof |
| JP5350620B2 (ja) * | 2006-11-24 | 2013-11-27 | キヤノン株式会社 | 粒子の製造方法、及び粒子 |
| US8293819B2 (en) | 2006-11-24 | 2012-10-23 | Canon Kabushiki Kaisha | Method for producing particles and particles |
| KR100816065B1 (ko) * | 2006-11-27 | 2008-03-24 | 동국제약 주식회사 | 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐 |
| JP5158835B2 (ja) * | 2006-12-06 | 2013-03-06 | 独立行政法人産業技術総合研究所 | 生分解性高分子リン酸カルシウム複合ナノ粒子及びその製造方法 |
| GB0625322D0 (en) * | 2006-12-19 | 2007-01-24 | Pharmakodex Ltd | Pharmaceutical compositions |
| CA2730760A1 (en) * | 2008-07-16 | 2010-01-21 | Surmodics Pharmaceuticals, Inc. | Process for preparing microparticles containing bioactive peptides |
| KR101113044B1 (ko) * | 2008-08-29 | 2012-02-27 | 동국제약 주식회사 | 용매교류증발법에 의한 서방출성 미립구의 제조방법 |
| CN101721370A (zh) * | 2008-10-10 | 2010-06-09 | 深圳清华大学研究院 | 戈舍瑞林缓释微球制剂及其制备方法、检测方法 |
| CA2742680C (en) * | 2008-11-07 | 2013-12-31 | Samyang Corporation | Pharmaceutical compositions for release control of methylphenidate |
| CN101461786A (zh) * | 2009-01-08 | 2009-06-24 | 上海交通大学 | 用水包油－油包固体制备的pla/plga壳－核微球及其制备方法 |
| GB201110601D0 (en) * | 2011-06-23 | 2011-08-03 | Controlled Therapeutics Scotland Ltd | Improved bioresorbable |
| UA112192C2 (uk) * | 2011-07-22 | 2016-08-10 | Іннокор Текнолоджис Б.В. | Здатні до біорозкладання напівкристалічні термопластичні мультиблокові співполімери з розділеними фазами для контрольованого вивільнення біологічно активних сполук |
-
2014
- 2014-04-16 JP JP2016507993A patent/JP6151848B2/ja active Active
- 2014-04-16 WO PCT/CN2014/075441 patent/WO2014169816A1/zh not_active Ceased
- 2014-04-16 EP EP14785916.9A patent/EP2987484B1/en active Active
- 2014-04-16 CN CN201410152866.4A patent/CN104107434B/zh active Active
- 2014-04-16 PL PL14785916T patent/PL2987484T3/pl unknown
- 2014-04-16 ES ES14785916T patent/ES2716384T3/es active Active
- 2014-04-16 RU RU2015149431A patent/RU2694901C2/ru active
-
2015
- 2015-10-08 US US14/877,976 patent/US20160022584A1/en not_active Abandoned
-
2017
- 2017-10-20 US US15/789,091 patent/US10258572B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2015149431A (ru) | 2017-05-24 |
| CN104107434B (zh) | 2017-02-01 |
| EP2987484B1 (en) | 2018-12-19 |
| EP2987484A4 (en) | 2017-03-08 |
| CN104107434A (zh) | 2014-10-22 |
| EP2987484A1 (en) | 2016-02-24 |
| US20180036246A1 (en) | 2018-02-08 |
| US20160022584A1 (en) | 2016-01-28 |
| ES2716384T3 (es) | 2019-06-12 |
| WO2014169816A1 (zh) | 2014-10-23 |
| JP2016516785A (ja) | 2016-06-09 |
| RU2694901C2 (ru) | 2019-07-18 |
| US10258572B2 (en) | 2019-04-16 |
| JP6151848B2 (ja) | 2017-06-21 |
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