IL228869B - Lysine in Streptococcus karyophage for the detection and treatment of gram-positive bacteria - Google Patents
Lysine in Streptococcus karyophage for the detection and treatment of gram-positive bacteriaInfo
- Publication number
- IL228869B IL228869B IL228869A IL22886913A IL228869B IL 228869 B IL228869 B IL 228869B IL 228869 A IL228869 A IL 228869A IL 22886913 A IL22886913 A IL 22886913A IL 228869 B IL228869 B IL 228869B
- Authority
- IL
- Israel
- Prior art keywords
- detection
- treatment
- positive bacteria
- gram positive
- bacteriophage lysins
- Prior art date
Links
- 241000192125 Firmicutes Species 0.000 title 1
- 241000194017 Streptococcus Species 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 241001515965 unidentified phage Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/50—Hydrolases (3) acting on carbon-nitrogen bonds, other than peptide bonds (3.5), e.g. asparaginase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161477836P | 2011-04-21 | 2011-04-21 | |
| PCT/US2012/034456 WO2012145630A2 (en) | 2011-04-21 | 2012-04-20 | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL228869A0 IL228869A0 (en) | 2013-12-31 |
| IL228869B true IL228869B (en) | 2019-05-30 |
Family
ID=47042182
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL228869A IL228869B (en) | 2011-04-21 | 2013-10-14 | Lysine in Streptococcus karyophage for the detection and treatment of gram-positive bacteria |
| IL266476A IL266476B (en) | 2011-04-21 | 2019-05-06 | Streptococcus bacteriophage lysins for the detection and treatment of gram-positive bacteria |
| IL271300A IL271300B (en) | 2011-04-21 | 2019-12-10 | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| IL287530A IL287530A (en) | 2011-04-21 | 2021-10-24 | Streptococcus bacteriophage lysins for the detection and treatment of gram-positive bacteria |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL266476A IL266476B (en) | 2011-04-21 | 2019-05-06 | Streptococcus bacteriophage lysins for the detection and treatment of gram-positive bacteria |
| IL271300A IL271300B (en) | 2011-04-21 | 2019-12-10 | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| IL287530A IL287530A (en) | 2011-04-21 | 2021-10-24 | Streptococcus bacteriophage lysins for the detection and treatment of gram-positive bacteria |
Country Status (12)
| Country | Link |
|---|---|
| US (7) | US9034322B2 (OSRAM) |
| EP (2) | EP2699253B1 (OSRAM) |
| JP (4) | JP6139509B2 (OSRAM) |
| CN (4) | CN103857410A (OSRAM) |
| AU (3) | AU2012245357B2 (OSRAM) |
| CA (1) | CA2833409A1 (OSRAM) |
| DK (1) | DK2699253T3 (OSRAM) |
| ES (1) | ES2682670T3 (OSRAM) |
| HK (2) | HK1244503A1 (OSRAM) |
| IL (4) | IL228869B (OSRAM) |
| MX (4) | MX383544B (OSRAM) |
| WO (1) | WO2012145630A2 (OSRAM) |
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| WO2012097313A2 (en) | 2011-01-14 | 2012-07-19 | The Regents Of The University Of California | Therapeutic antibodies against ror-1 protein and methods for use of same |
| US20140179594A1 (en) * | 2011-04-21 | 2014-06-26 | The Rockefeller University | Streptococcus bacteriophage lysins for treatment of gram positive bacteria in companion animals and livestock |
| NL2007038C2 (en) * | 2011-07-04 | 2013-01-07 | Vereniging Voor Christelijk Hoger Onderwijs | System and method for predicting the viability of a body tissue in a patient, and measuring device used therein. |
| KR102084388B1 (ko) | 2012-05-09 | 2020-03-06 | 콘트라펙트 코포레이션 | 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료 |
| KR20230113404A (ko) * | 2012-05-09 | 2023-07-28 | 콘트라펙트 코포레이션 | 그람 양성 박테리아에 대한 박테리오파지 리신과 항생제의병용물 |
| CN104073478A (zh) * | 2014-06-13 | 2014-10-01 | 上海交通大学 | 杀灭革兰氏阳性菌的酶抗生素及其制备、用途 |
| RU2725809C2 (ru) | 2014-06-26 | 2020-07-06 | Дзе Рокфеллер Юниверсити | Лизины ацинетобактеров |
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| KR102073094B1 (ko) * | 2018-06-04 | 2020-02-04 | (주)인트론바이오테크놀로지 | 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-3 및 이의 스트렙토코커스 수이스 균 증식 억제 용도 |
| KR102073088B1 (ko) * | 2018-06-04 | 2020-02-04 | (주)인트론바이오테크놀로지 | 신규한 스트렙토코커스 수이스 박테리오파지 Str-SUP-2 및 이의 스트렙토코커스 수이스 균 증식 억제 용도 |
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| US11674961B2 (en) | 2018-10-12 | 2023-06-13 | Quidel Corporation | Extraction reagent for use in an assay for detection of group A Streptococcus |
| AU2020244764A1 (en) * | 2019-03-22 | 2021-10-14 | Contrafect Corporation | Method of treating infective endocarditis |
| AU2020256258A1 (en) * | 2019-04-05 | 2021-11-04 | Contrafect Corporation | Lysins and derivatives thereof with bactericidal activity against Pseudomonas aeruginosa, in the presence of human serum |
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| CN112760312B (zh) * | 2021-01-20 | 2022-06-17 | 华中农业大学 | 一种裂解革兰氏阳性菌的裂解酶plyssX609及其应用 |
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| KR101016918B1 (ko) * | 2009-01-08 | 2011-02-25 | 주식회사 인트론바이오테크놀로지 | 박테리아 특이적 넓은 항균 활성을 갖는 신규한 리신 단백질 |
| CN103080307A (zh) * | 2010-01-25 | 2013-05-01 | 美艾利尔斯卡保罗有限公司 | A25噬菌体溶解酶 |
| US20140179594A1 (en) * | 2011-04-21 | 2014-06-26 | The Rockefeller University | Streptococcus bacteriophage lysins for treatment of gram positive bacteria in companion animals and livestock |
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