IL226647A - Liquid viral formulations - Google Patents

Info

Publication number

IL226647A

IL226647A IL226647A IL22664713A IL226647A IL 226647 A IL226647 A IL 226647A IL 226647 A IL226647 A IL 226647A IL 22664713 A IL22664713 A IL 22664713A IL 226647 A IL226647 A IL 226647A

Authority

IL

Israel

Prior art keywords

viral

formulation

virus

reovirus

composition

Prior art date

2010-12-02

Links

• Espacenet
• Global Dossier
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• 230000003612 virological effect Effects 0.000 title claims description 230
• 238000009472 formulation Methods 0.000 title claims description 206
• 239000007788 liquid Substances 0.000 title claims description 88
• 241000700605 Viruses Species 0.000 claims description 68
• 241000702263 Reovirus sp. Species 0.000 claims description 55
• 238000000034 method Methods 0.000 claims description 45
• 229930006000 Sucrose Natural products 0.000 claims description 18
• 239000005720 sucrose Substances 0.000 claims description 18
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• 238000001802 infusion Methods 0.000 claims description 17
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• FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 16
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• 239000000594 mannitol Substances 0.000 claims description 16
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• FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 15
• 241000282414 Homo sapiens Species 0.000 claims description 15
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• TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 12
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