IL219056A - Pirphenidone for therapies with 450p cytochrome prevention factors - Google Patents
Pirphenidone for therapies with 450p cytochrome prevention factorsInfo
- Publication number
- IL219056A IL219056A IL219056A IL21905612A IL219056A IL 219056 A IL219056 A IL 219056A IL 219056 A IL219056 A IL 219056A IL 21905612 A IL21905612 A IL 21905612A IL 219056 A IL219056 A IL 219056A
- Authority
- IL
- Israel
- Prior art keywords
- pirfenidone
- inducers
- cytochrome
- avoidance
- therapy
- Prior art date
Links
- 239000000411 inducer Substances 0.000 title abstract 2
- ISWRGOKTTBVCFA-UHFFFAOYSA-N pirfenidone Chemical compound C1=C(C)C=CC(=O)N1C1=CC=CC=C1 ISWRGOKTTBVCFA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003073 pirfenidone Drugs 0.000 title abstract 2
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 title 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 206010013710 Drug interaction Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000000391 smoking effect Effects 0.000 abstract 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Surgery (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26675309P | 2009-12-04 | 2009-12-04 | |
US12/684,543 US8084475B2 (en) | 2009-12-04 | 2010-01-08 | Pirfenidone therapy and inducers of cytochrome P450 |
EP10250378A EP2308491B1 (de) | 2009-12-04 | 2010-03-03 | Pirfenidontheraphy und Cytochrom-P450-Induktoren |
US31057510P | 2010-03-04 | 2010-03-04 | |
CA2710014A CA2710014C (en) | 2009-12-04 | 2010-08-17 | Pirfenidone therapy and inducers of cytochrome p450 |
PCT/US2010/058936 WO2011069089A1 (en) | 2009-12-04 | 2010-12-03 | Pirfenidone therapy and inducers of cytochrome p450 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL219056A0 IL219056A0 (en) | 2012-06-28 |
IL219056A true IL219056A (en) | 2017-03-30 |
Family
ID=42077364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL219056A IL219056A (en) | 2009-12-04 | 2012-04-04 | Pirphenidone for therapies with 450p cytochrome prevention factors |
Country Status (27)
Country | Link |
---|---|
US (3) | US8084475B2 (de) |
EP (3) | EP2308491B1 (de) |
JP (3) | JP5753094B2 (de) |
KR (2) | KR101762465B1 (de) |
AT (1) | ATE523197T1 (de) |
AU (1) | AU2010212488B2 (de) |
CA (1) | CA2710014C (de) |
CY (1) | CY1112075T1 (de) |
DK (1) | DK2308491T3 (de) |
EA (1) | EA026869B1 (de) |
ES (1) | ES2395159T3 (de) |
GE (1) | GEP20166426B (de) |
HK (1) | HK1151725A1 (de) |
HR (1) | HRP20110853T1 (de) |
IL (1) | IL219056A (de) |
MX (1) | MX2012004528A (de) |
NZ (1) | NZ599246A (de) |
PE (1) | PE20121348A1 (de) |
PL (1) | PL2308491T3 (de) |
PT (1) | PT2308491E (de) |
RS (1) | RS51976B (de) |
SG (1) | SG181128A1 (de) |
SI (1) | SI2308491T1 (de) |
SM (1) | SMT201200003B (de) |
TW (2) | TWI440459B (de) |
WO (1) | WO2011069089A1 (de) |
ZA (1) | ZA201202553B (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8084475B2 (en) * | 2009-12-04 | 2011-12-27 | Intermune, Inc. | Pirfenidone therapy and inducers of cytochrome P450 |
US7816383B1 (en) | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
ES2913095T3 (es) | 2011-01-31 | 2022-05-31 | Avalyn Pharma Inc | Compuestos de pirfenidona y análogos de piridona en aerosol y usos de los mismos |
CA2819967C (en) | 2012-08-31 | 2016-03-22 | Intermune, Inc. | Use of pirfenidone concomitantly with ciprofloxacin |
AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
CN104812338B (zh) | 2012-11-16 | 2017-09-29 | 茵秋创新有限责任公司 | 斜向膨胀式融合器设备和方法 |
US9682071B2 (en) | 2013-03-15 | 2017-06-20 | Intermune, Inc. | Methods of improving microvascular integrity |
EP3711715B1 (de) | 2013-03-15 | 2024-04-24 | Spine Forward, Llc | System mit expandierbarem fusionskäfig |
AU2015204558B2 (en) | 2014-01-10 | 2020-04-30 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
JP6525437B2 (ja) | 2014-04-02 | 2019-06-05 | インターミューン, インコーポレイテッド | 抗線維性ピリジノン |
CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
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KR20090024834A (ko) * | 2006-07-05 | 2009-03-09 | 인터뮨, 인크. | C형 간염 바이러스 복제의 신규 억제제 |
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