SI2308491T1 - Terapija s pirfenidonom in induktorji citokroma p450 - Google Patents
Terapija s pirfenidonom in induktorji citokroma p450Info
- Publication number
- SI2308491T1 SI2308491T1 SI201030011T SI201030011T SI2308491T1 SI 2308491 T1 SI2308491 T1 SI 2308491T1 SI 201030011 T SI201030011 T SI 201030011T SI 201030011 T SI201030011 T SI 201030011T SI 2308491 T1 SI2308491 T1 SI 2308491T1
- Authority
- SI
- Slovenia
- Prior art keywords
- inducers
- cytochrome
- pirfenidone therapy
- pirfenidone
- therapy
- Prior art date
Links
- 239000000411 inducer Substances 0.000 title abstract 2
- ISWRGOKTTBVCFA-UHFFFAOYSA-N pirfenidone Chemical compound C1=C(C)C=CC(=O)N1C1=CC=CC=C1 ISWRGOKTTBVCFA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003073 pirfenidone Drugs 0.000 title abstract 2
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 title 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 206010013710 Drug interaction Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000000391 smoking effect Effects 0.000 abstract 1
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- Health & Medical Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26675309P | 2009-12-04 | 2009-12-04 | |
| US12/684,543 US8084475B2 (en) | 2009-12-04 | 2010-01-08 | Pirfenidone therapy and inducers of cytochrome P450 |
| EP10250378A EP2308491B1 (en) | 2009-12-04 | 2010-03-03 | Pirfenidone therapy and inducers of cytochrome P450 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2308491T1 true SI2308491T1 (sl) | 2011-12-30 |
Family
ID=42077364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201030011T SI2308491T1 (sl) | 2009-12-04 | 2010-03-03 | Terapija s pirfenidonom in induktorji citokroma p450 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US8084475B2 (sl) |
| EP (3) | EP2377537A1 (sl) |
| JP (3) | JP5753094B2 (sl) |
| KR (2) | KR101762465B1 (sl) |
| AT (1) | ATE523197T1 (sl) |
| AU (1) | AU2010212488B2 (sl) |
| CA (1) | CA2710014C (sl) |
| CY (1) | CY1112075T1 (sl) |
| DK (1) | DK2308491T3 (sl) |
| EA (1) | EA026869B1 (sl) |
| ES (1) | ES2395159T3 (sl) |
| GE (1) | GEP20166426B (sl) |
| HK (1) | HK1151725A1 (sl) |
| HR (1) | HRP20110853T1 (sl) |
| IL (1) | IL219056A (sl) |
| MX (1) | MX2012004528A (sl) |
| NZ (1) | NZ599246A (sl) |
| PE (1) | PE20121348A1 (sl) |
| PL (1) | PL2308491T3 (sl) |
| PT (1) | PT2308491E (sl) |
| RS (1) | RS51976B (sl) |
| SG (1) | SG181128A1 (sl) |
| SI (1) | SI2308491T1 (sl) |
| SM (1) | SMT201200003B (sl) |
| TW (2) | TW201315718A (sl) |
| WO (1) | WO2011069089A1 (sl) |
| ZA (1) | ZA201202553B (sl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7816383B1 (en) | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
| US8084475B2 (en) | 2009-12-04 | 2011-12-27 | Intermune, Inc. | Pirfenidone therapy and inducers of cytochrome P450 |
| US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| DK2670242T3 (da) | 2011-01-31 | 2022-05-02 | Avalyn Pharma Inc | Aerosolpirfenidon- og pyridonanalogforbindelser og anvendelser deraf |
| CA2819967C (en) | 2012-08-31 | 2016-03-22 | Intermune, Inc. | Use of pirfenidone concomitantly with ciprofloxacin |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| US9907671B2 (en) | 2012-11-16 | 2018-03-06 | In Queue Innovations, Llc | Oblique expanding fusion cage device and method |
| WO2014151517A1 (en) * | 2013-03-15 | 2014-09-25 | Intermune, Inc. | Methods of improving microvascular integrity |
| WO2014144696A1 (en) | 2013-03-15 | 2014-09-18 | Lanx, Inc. | Expandable fusion cage system |
| CA2936330C (en) | 2014-01-10 | 2023-01-03 | Genoa Pharmaceuticals Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| CN106459042B (zh) | 2014-04-02 | 2019-06-28 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
| CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
| WO2021057599A1 (zh) * | 2019-09-26 | 2021-04-01 | 深圳先进技术研究院 | 吡非尼酮在制备防治类风湿性关节炎的药物中的应用 |
| CN111991393A (zh) * | 2019-09-26 | 2020-11-27 | 深圳先进技术研究院 | 吡非尼酮在制备防治类风湿性关节炎的药物中的应用 |
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| US20070072181A1 (en) * | 2003-02-28 | 2007-03-29 | Blatt Lawrence M | Combination therapy for treating alphavirus infection and liver fibrosis |
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