PL2308491T3 - Terapia pirfenidonem i induktory cytochromu P 450 - Google Patents
Terapia pirfenidonem i induktory cytochromu P 450Info
- Publication number
- PL2308491T3 PL2308491T3 PL10250378T PL10250378T PL2308491T3 PL 2308491 T3 PL2308491 T3 PL 2308491T3 PL 10250378 T PL10250378 T PL 10250378T PL 10250378 T PL10250378 T PL 10250378T PL 2308491 T3 PL2308491 T3 PL 2308491T3
- Authority
- PL
- Poland
- Prior art keywords
- inducers
- cytochrome
- pirfenidone therapy
- pirfenidone
- therapy
- Prior art date
Links
- 239000000411 inducer Substances 0.000 title abstract 2
- ISWRGOKTTBVCFA-UHFFFAOYSA-N pirfenidone Chemical compound C1=C(C)C=CC(=O)N1C1=CC=CC=C1 ISWRGOKTTBVCFA-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003073 pirfenidone Drugs 0.000 title abstract 2
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 title 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 206010013710 Drug interaction Diseases 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000000391 smoking effect Effects 0.000 abstract 1
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
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- Organic Chemistry (AREA)
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- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- AIDS & HIV (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26675309P | 2009-12-04 | 2009-12-04 | |
| US12/684,543 US8084475B2 (en) | 2009-12-04 | 2010-01-08 | Pirfenidone therapy and inducers of cytochrome P450 |
| EP10250378A EP2308491B1 (en) | 2009-12-04 | 2010-03-03 | Pirfenidone therapy and inducers of cytochrome P450 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2308491T3 true PL2308491T3 (pl) | 2012-02-29 |
Family
ID=42077364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10250378T PL2308491T3 (pl) | 2009-12-04 | 2010-03-03 | Terapia pirfenidonem i induktory cytochromu P 450 |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US8084475B2 (pl) |
| EP (3) | EP2377537A1 (pl) |
| JP (3) | JP5753094B2 (pl) |
| KR (2) | KR101762465B1 (pl) |
| AT (1) | ATE523197T1 (pl) |
| AU (1) | AU2010212488B2 (pl) |
| CA (1) | CA2710014C (pl) |
| CY (1) | CY1112075T1 (pl) |
| DK (1) | DK2308491T3 (pl) |
| EA (1) | EA026869B1 (pl) |
| ES (1) | ES2395159T3 (pl) |
| GE (1) | GEP20166426B (pl) |
| HK (1) | HK1151725A1 (pl) |
| HR (1) | HRP20110853T1 (pl) |
| IL (1) | IL219056A (pl) |
| MX (1) | MX2012004528A (pl) |
| NZ (1) | NZ599246A (pl) |
| PE (1) | PE20121348A1 (pl) |
| PL (1) | PL2308491T3 (pl) |
| PT (1) | PT2308491E (pl) |
| RS (1) | RS51976B (pl) |
| SG (1) | SG181128A1 (pl) |
| SI (1) | SI2308491T1 (pl) |
| SM (1) | SMT201200003B (pl) |
| TW (2) | TWI440459B (pl) |
| WO (1) | WO2011069089A1 (pl) |
| ZA (1) | ZA201202553B (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7816383B1 (en) | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
| US8084475B2 (en) | 2009-12-04 | 2011-12-27 | Intermune, Inc. | Pirfenidone therapy and inducers of cytochrome P450 |
| US10092552B2 (en) | 2011-01-31 | 2018-10-09 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| CA2819967C (en) | 2012-08-31 | 2016-03-22 | Intermune, Inc. | Use of pirfenidone concomitantly with ciprofloxacin |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| US9907671B2 (en) | 2012-11-16 | 2018-03-06 | In Queue Innovations, Llc | Oblique expanding fusion cage device and method |
| WO2014151517A1 (en) * | 2013-03-15 | 2014-09-25 | Intermune, Inc. | Methods of improving microvascular integrity |
| EP3711715B1 (en) | 2013-03-15 | 2024-04-24 | Spine Forward, Llc | Expandable fusion cage system |
| AU2015204558B2 (en) | 2014-01-10 | 2020-04-30 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| EP3126362B1 (en) | 2014-04-02 | 2022-01-12 | Intermune, Inc. | Anti-fibrotic pyridinones |
| CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
| CN111991393A (zh) * | 2019-09-26 | 2020-11-27 | 深圳先进技术研究院 | 吡非尼酮在制备防治类风湿性关节炎的药物中的应用 |
| WO2021057599A1 (zh) * | 2019-09-26 | 2021-04-01 | 深圳先进技术研究院 | 吡非尼酮在制备防治类风湿性关节炎的药物中的应用 |
| JP2023504415A (ja) | 2019-12-04 | 2023-02-03 | イドーシア ファーマシューティカルズ リミテッド | 線維性疾患の治療に使用するためのアゼチジンｌｐａ１受容体アンタゴニストのピルフェニドン及び／又はニンテダニブとの合剤 |
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| US5330562A (en) * | 1993-03-12 | 1994-07-19 | Medx, Inc. | Fluidized bed scrubber for use in gas cleaning system |
| WO2004019863A2 (en) | 2002-08-28 | 2004-03-11 | Intermune, Inc. | Combination therapy for treatment of fibrotic disorders |
| JP4542743B2 (ja) * | 2002-12-26 | 2010-09-15 | Ｋｄｌ株式会社 | ピリドン誘導体の溶液状医薬組成物 |
| WO2005013917A2 (en) | 2003-02-28 | 2005-02-17 | Intermune, Inc. | Combination therapy for treating alphavirus infection and liver fibrosis |
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| US20070053877A1 (en) | 2003-08-21 | 2007-03-08 | Intermune, Inc. | Methods of treating idiopathic pulmonary fibrosis |
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| CN1846699A (zh) | 2005-04-13 | 2006-10-18 | 中南大学湘雅医院 | 1－(取代苯基)－5－甲基－2－(1h) 吡啶酮(i)化合物用于制备抗除肾间质纤维化外其他器官纤维化或组织纤维化药物的应用 |
| KR101294467B1 (ko) | 2005-07-25 | 2013-09-09 | 인터뮨, 인크. | Ｃ형 간염 바이러스 복제의 신규 거대고리형 억제제 |
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| RU2008152171A (ru) | 2006-07-05 | 2010-08-10 | Интермьюн, Инк. (Us) | Новые ингибиторы вирусной репликации гепатита с |
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