IL217740B - Method to improve virus removal in protein purification - Google Patents
Method to improve virus removal in protein purificationInfo
- Publication number
- IL217740B IL217740B IL217740A IL21774012A IL217740B IL 217740 B IL217740 B IL 217740B IL 217740 A IL217740 A IL 217740A IL 21774012 A IL21774012 A IL 21774012A IL 217740 B IL217740 B IL 217740B
- Authority
- IL
- Israel
- Prior art keywords
- viruses
- proteins
- purification
- removal
- improve
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23181109P | 2009-08-06 | 2009-08-06 | |
| PCT/US2010/044760 WO2011031397A1 (en) | 2009-08-06 | 2010-08-06 | Method to improve virus removal in protein purification |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL217740A0 IL217740A0 (en) | 2012-03-29 |
| IL217740B true IL217740B (en) | 2020-04-30 |
Family
ID=42985499
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL217740A IL217740B (en) | 2009-08-06 | 2012-01-26 | Method to improve virus removal in protein purification |
| IL273486A IL273486B (en) | 2009-08-06 | 2020-03-22 | A method to improve the removal of viruses in the purification of proteins |
| IL287431A IL287431A (en) | 2009-08-06 | 2021-10-20 | A method to improve the removal of viruses in the purification of proteins |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL273486A IL273486B (en) | 2009-08-06 | 2020-03-22 | A method to improve the removal of viruses in the purification of proteins |
| IL287431A IL287431A (en) | 2009-08-06 | 2021-10-20 | A method to improve the removal of viruses in the purification of proteins |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US10662237B2 (de) |
| EP (3) | EP4559926A3 (de) |
| JP (6) | JP2013501075A (de) |
| KR (3) | KR20190018041A (de) |
| CN (2) | CN102712691A (de) |
| AU (1) | AU2010292897B2 (de) |
| BR (1) | BR112012002574A2 (de) |
| CA (1) | CA2770235C (de) |
| DK (1) | DK2462158T3 (de) |
| ES (1) | ES2662529T3 (de) |
| HR (1) | HRP20180309T1 (de) |
| HU (1) | HUE038451T2 (de) |
| IL (3) | IL217740B (de) |
| LT (1) | LT2462158T (de) |
| MX (1) | MX346115B (de) |
| MY (1) | MY188566A (de) |
| NO (1) | NO2462158T3 (de) |
| NZ (1) | NZ597809A (de) |
| PL (1) | PL2462158T3 (de) |
| PT (1) | PT2462158T (de) |
| RU (1) | RU2573894C2 (de) |
| SG (1) | SG178276A1 (de) |
| SI (1) | SI2462158T1 (de) |
| WO (1) | WO2011031397A1 (de) |
| ZA (1) | ZA201200626B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2842964A1 (en) | 2006-09-13 | 2008-03-20 | Abbvie Inc. | Cell culture improvements |
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| AU2009307737B2 (en) | 2008-10-20 | 2015-07-23 | Abbvie Inc. | Viral inactivation during purification of antibodies |
| NZ592095A (en) | 2008-10-20 | 2013-01-25 | Abbott Lab | Isolation and purification of il-12 and tnf-alpha antibodies using protein a affinity chromatography |
| SI2462158T1 (en) * | 2009-08-06 | 2018-04-30 | F. Hoffmann-La Roche Ag | Method to improve virus removal in protein purification |
| TW201302793A (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
| RU2013147609A (ru) * | 2011-03-25 | 2015-04-27 | Дженентек, Инк. | Новые способы очистки белка |
| DE102011105525B4 (de) * | 2011-06-24 | 2015-03-26 | Sartorius Stedim Biotech Gmbh | Verfahren zur Abtrennung von Biopolymer-Aggregaten und Viren aus einem Fluid |
| WO2013028330A2 (en) | 2011-08-19 | 2013-02-28 | Emd Millipore Corporation | Methods of reducing level of one of more impurities in a sample during protein purification |
| HRP20181846T1 (hr) | 2011-12-22 | 2018-12-28 | Genentech, Inc. | Kromatografija membranom za ionsku izmjenu |
| NZ756750A (en) | 2013-09-13 | 2022-05-27 | Genentech Inc | Methods and compositions comprising purified recombinant polypeptides |
| ES2915378T3 (es) | 2013-09-13 | 2022-06-22 | Hoffmann La Roche | Procedimientos para detectar y cuantificar una proteína de célula huésped en líneas celulares |
| MX383595B (es) * | 2014-10-21 | 2025-03-14 | Gennova Biopharmaceuticals Ltd | Proceso novedoso de purificacion para el aislamiento y produccion comercial de tnk-tpa recombinante (tenecteplasa) |
| JP7133925B2 (ja) * | 2015-03-23 | 2022-09-09 | アレクシオン ファーマシューティカルズ インコーポレイテッド | ウイルス濾過 |
| WO2018230397A1 (ja) * | 2017-06-12 | 2018-12-20 | 旭化成メディカル株式会社 | タンパク質含有液のろ過方法 |
| EP3728288B1 (de) * | 2017-12-21 | 2022-01-19 | Genzyme Corporation | Verfahren zur verbesserten entfernung von verunreinigungen während der protein-a-chromatographie |
| TWI871300B (zh) * | 2019-01-28 | 2025-02-01 | 美商安進公司 | 藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程 |
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2010
- 2010-08-06 SI SI201031646T patent/SI2462158T1/en unknown
- 2010-08-06 JP JP2012523983A patent/JP2013501075A/ja not_active Withdrawn
- 2010-08-06 HR HRP20180309TT patent/HRP20180309T1/hr unknown
- 2010-08-06 KR KR1020197004167A patent/KR20190018041A/ko not_active Ceased
- 2010-08-06 EP EP24217316.9A patent/EP4559926A3/de active Pending
- 2010-08-06 SG SG2012008157A patent/SG178276A1/en unknown
- 2010-08-06 WO PCT/US2010/044760 patent/WO2011031397A1/en not_active Ceased
- 2010-08-06 CA CA2770235A patent/CA2770235C/en active Active
- 2010-08-06 LT LTEP10740823.9T patent/LT2462158T/lt unknown
- 2010-08-06 RU RU2012108318/10A patent/RU2573894C2/ru active
- 2010-08-06 EP EP10740823.9A patent/EP2462158B1/de active Active
- 2010-08-06 NZ NZ597809A patent/NZ597809A/en unknown
- 2010-08-06 AU AU2010292897A patent/AU2010292897B2/en active Active
- 2010-08-06 NO NO10740823A patent/NO2462158T3/no unknown
- 2010-08-06 BR BR112012002574-0A patent/BR112012002574A2/pt not_active Application Discontinuation
- 2010-08-06 CN CN2010800447903A patent/CN102712691A/zh active Pending
- 2010-08-06 HU HUE10740823A patent/HUE038451T2/hu unknown
- 2010-08-06 EP EP17195123.9A patent/EP3309168A1/de active Pending
- 2010-08-06 MY MYPI2012000500A patent/MY188566A/en unknown
- 2010-08-06 ES ES10740823.9T patent/ES2662529T3/es active Active
- 2010-08-06 KR KR1020187008767A patent/KR20180035936A/ko not_active Ceased
- 2010-08-06 MX MX2012001659A patent/MX346115B/es active IP Right Grant
- 2010-08-06 DK DK10740823.9T patent/DK2462158T3/en active
- 2010-08-06 PL PL10740823T patent/PL2462158T3/pl unknown
- 2010-08-06 KR KR1020127005754A patent/KR101844859B1/ko active Active
- 2010-08-06 CN CN201710110829.0A patent/CN106905413A/zh active Pending
- 2010-08-06 PT PT107408239T patent/PT2462158T/pt unknown
- 2010-08-06 US US12/806,171 patent/US10662237B2/en active Active
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2012
- 2012-01-25 ZA ZA2012/00626A patent/ZA201200626B/en unknown
- 2012-01-26 IL IL217740A patent/IL217740B/en active IP Right Grant
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2015
- 2015-12-25 JP JP2015252787A patent/JP2016106096A/ja active Pending
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2017
- 2017-06-21 JP JP2017121588A patent/JP2017206529A/ja active Pending
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2019
- 2019-09-09 JP JP2019163497A patent/JP2020023491A/ja not_active Withdrawn
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2020
- 2020-03-22 IL IL273486A patent/IL273486B/en unknown
- 2020-04-14 US US16/848,564 patent/US11225513B2/en active Active
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2021
- 2021-10-20 IL IL287431A patent/IL287431A/en unknown
- 2021-12-07 US US17/544,796 patent/US20220306726A1/en not_active Abandoned
-
2022
- 2022-11-21 JP JP2022185354A patent/JP2023029853A/ja not_active Withdrawn
-
2023
- 2023-11-21 US US18/298,233 patent/US20240083980A1/en not_active Abandoned
-
2024
- 2024-09-13 JP JP2024159627A patent/JP2025003999A/ja active Pending
-
2025
- 2025-05-19 US US19/212,175 patent/US20250282850A1/en active Pending
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