IL210907A - Process for Isolating Enantiomer Components from Enantiomers (r) and (s) by Formulation Controlled by Particle Size - Google Patents
Process for Isolating Enantiomer Components from Enantiomers (r) and (s) by Formulation Controlled by Particle SizeInfo
- Publication number
- IL210907A IL210907A IL210907A IL21090711A IL210907A IL 210907 A IL210907 A IL 210907A IL 210907 A IL210907 A IL 210907A IL 21090711 A IL21090711 A IL 21090711A IL 210907 A IL210907 A IL 210907A
- Authority
- IL
- Israel
- Prior art keywords
- enantiomer
- crystals
- mixture
- enantiomers
- crystallization
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
- C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/08—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
- C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
- C07C29/78—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by condensation or crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/26—Polyhydroxylic alcohols containing only six-membered aromatic rings as cyclic part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/10—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08013586 | 2008-07-29 | ||
| PCT/EP2009/059769 WO2010012746A2 (fr) | 2008-07-29 | 2009-07-28 | Procédé permettant, dans des mélanges d'énantiomères, d'extraire des énantiomères par cristallisation à contrôle des calibres particulaires |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL210907A0 IL210907A0 (en) | 2011-04-28 |
| IL210907A true IL210907A (en) | 2014-11-30 |
Family
ID=41412444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL210907A IL210907A (en) | 2008-07-29 | 2011-01-27 | Process for Isolating Enantiomer Components from Enantiomers (r) and (s) by Formulation Controlled by Particle Size |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US20110184169A1 (fr) |
| EP (1) | EP2344435B1 (fr) |
| JP (1) | JP5901292B2 (fr) |
| KR (1) | KR101659053B1 (fr) |
| CN (1) | CN102112425B (fr) |
| AU (1) | AU2009275963B2 (fr) |
| BR (1) | BRPI0916197B1 (fr) |
| CA (1) | CA2732157C (fr) |
| CY (1) | CY1117465T1 (fr) |
| DK (1) | DK2344435T3 (fr) |
| EA (1) | EA018508B1 (fr) |
| ES (1) | ES2569105T3 (fr) |
| HR (1) | HRP20160318T1 (fr) |
| HU (1) | HUE028587T2 (fr) |
| IL (1) | IL210907A (fr) |
| MX (1) | MX2011001004A (fr) |
| PL (1) | PL2344435T3 (fr) |
| RS (1) | RS54669B1 (fr) |
| SI (1) | SI2344435T1 (fr) |
| SM (1) | SMT201600113B (fr) |
| WO (1) | WO2010012746A2 (fr) |
| ZA (1) | ZA201101502B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2344435T1 (sl) | 2008-07-29 | 2016-05-31 | Poxel | Proces izolacije enantiomernih spojin iz enantiomernih mešanic s kristalizacijo nadzorovano z velikostjo delcev |
| ES2436633T3 (es) * | 2009-03-26 | 2014-01-03 | Poxel | Procedimiento para la separación de enantiómeros de dihidro-1,3,5-triazinas racémicas por cristalización preferencial |
| KR20200102982A (ko) | 2017-10-02 | 2020-09-01 | 폭셀 | 보존된 박출률을 갖는 심부전의 치료 방법 |
| MX2020013210A (es) | 2018-06-06 | 2021-02-26 | Metavant Sciences Gmbh | Metodos de tratamiento de sujetos que padecen diabetes con enfermedad renal cronica. |
| JP7266616B2 (ja) | 2018-06-14 | 2023-04-28 | ポクセル | 糖尿病の治療において使用するためのトリアジン誘導体を含むフィルムコーティング錠剤 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB796343A (en) | 1955-05-31 | 1958-06-11 | Kellogg M W Co | Improvements in or relating to method of purifying sulphuric acid by fractional crystallization |
| GB865311A (en) | 1958-09-28 | 1961-04-12 | Ajinomoto Kk | Process for continuous resolution of racemic amino acids |
| SU359878A1 (fr) | 1970-07-23 | 1974-05-15 | ||
| GB1455710A (en) | 1973-12-31 | 1976-11-17 | Ward Blenkinsop & Co Ltd | Resolution of optically active compounds |
| IT1222013B (it) * | 1987-07-10 | 1990-08-31 | Chimica Profarmaco Spa Ind | Processo di risoluzione ottica di acido 2 (6 metossi 2 naftil) propionico |
| GB9126832D0 (en) | 1991-12-18 | 1992-02-19 | Sandoz Ltd | Separation process |
| EP0777651A1 (fr) | 1994-08-19 | 1997-06-11 | Chiroscience Limited | Procede de separation des enantiomeres d'un lactame bicyclique |
| WO1997032644A1 (fr) | 1996-03-10 | 1997-09-12 | Reuter Chemische Apparatebau | Procede de separation |
| NL1004346C2 (nl) * | 1996-10-23 | 1998-04-24 | Dsm Nv | Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel. |
| ATE327019T1 (de) | 1997-09-06 | 2006-06-15 | Reuter Chemische Appbau Kg | Trennverfahren |
| EP1034826A1 (fr) | 1999-03-05 | 2000-09-13 | Reuter Chemische Apparatebau | Procédé de co-cristallisation |
| PT1161290E (pt) | 1999-03-17 | 2007-12-14 | Reuter Chemische Appbau Kg | Cristalização de emulsões com reciclagem |
| FR2853650B1 (fr) * | 2003-04-10 | 2006-07-07 | Merck Sante Sas | Procede de dedoublement d'amines utiles pour le traitement de desordres associes au syndrome d'insulino-resistance |
| JP2005324082A (ja) * | 2004-05-12 | 2005-11-24 | Mitsubishi Chemicals Corp | 同時分割法による化合物の相互分離方法 |
| SI2344435T1 (sl) | 2008-07-29 | 2016-05-31 | Poxel | Proces izolacije enantiomernih spojin iz enantiomernih mešanic s kristalizacijo nadzorovano z velikostjo delcev |
-
2009
- 2009-07-28 SI SI200931413A patent/SI2344435T1/sl unknown
- 2009-07-28 EA EA201100273A patent/EA018508B1/ru not_active IP Right Cessation
- 2009-07-28 DK DK09781210.1T patent/DK2344435T3/en active
- 2009-07-28 BR BRPI0916197-0A patent/BRPI0916197B1/pt not_active IP Right Cessation
- 2009-07-28 PL PL09781210T patent/PL2344435T3/pl unknown
- 2009-07-28 HU HUE09781210A patent/HUE028587T2/en unknown
- 2009-07-28 MX MX2011001004A patent/MX2011001004A/es active IP Right Grant
- 2009-07-28 KR KR1020117004547A patent/KR101659053B1/ko active IP Right Grant
- 2009-07-28 EP EP09781210.1A patent/EP2344435B1/fr active Active
- 2009-07-28 CA CA2732157A patent/CA2732157C/fr not_active Expired - Fee Related
- 2009-07-28 WO PCT/EP2009/059769 patent/WO2010012746A2/fr active Application Filing
- 2009-07-28 RS RS20160213A patent/RS54669B1/en unknown
- 2009-07-28 US US12/737,613 patent/US20110184169A1/en not_active Abandoned
- 2009-07-28 AU AU2009275963A patent/AU2009275963B2/en not_active Ceased
- 2009-07-28 ES ES09781210.1T patent/ES2569105T3/es active Active
- 2009-07-28 JP JP2011520493A patent/JP5901292B2/ja active Active
- 2009-07-28 CN CN200980130014.2A patent/CN102112425B/zh active Active
-
2011
- 2011-01-27 IL IL210907A patent/IL210907A/en active IP Right Grant
- 2011-02-25 ZA ZA2011/01502A patent/ZA201101502B/en unknown
-
2013
- 2013-08-26 US US13/975,744 patent/US8846911B2/en not_active Expired - Fee Related
-
2016
- 2016-03-29 HR HRP20160318TT patent/HRP20160318T1/hr unknown
- 2016-04-19 SM SM201600113T patent/SMT201600113B/it unknown
- 2016-04-19 CY CY20161100328T patent/CY1117465T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI2344435T1 (sl) | 2016-05-31 |
| CA2732157A1 (fr) | 2010-02-04 |
| US20130345421A1 (en) | 2013-12-26 |
| BRPI0916197B1 (pt) | 2018-01-23 |
| JP5901292B2 (ja) | 2016-04-06 |
| CA2732157C (fr) | 2016-04-12 |
| AU2009275963A1 (en) | 2010-02-04 |
| CY1117465T1 (el) | 2017-04-26 |
| AU2009275963B2 (en) | 2014-07-10 |
| WO2010012746A2 (fr) | 2010-02-04 |
| CN102112425B (zh) | 2014-06-11 |
| EA018508B1 (ru) | 2013-08-30 |
| RS54669B1 (en) | 2016-08-31 |
| EA201100273A1 (ru) | 2011-08-30 |
| IL210907A0 (en) | 2011-04-28 |
| KR101659053B1 (ko) | 2016-09-23 |
| WO2010012746A3 (fr) | 2010-08-05 |
| US8846911B2 (en) | 2014-09-30 |
| DK2344435T3 (en) | 2016-04-18 |
| SMT201600113B (it) | 2016-07-01 |
| KR20110059709A (ko) | 2011-06-03 |
| ZA201101502B (en) | 2011-10-26 |
| EP2344435B1 (fr) | 2016-03-23 |
| EP2344435A2 (fr) | 2011-07-20 |
| ES2569105T3 (es) | 2016-05-06 |
| HRP20160318T1 (hr) | 2016-05-06 |
| HUE028587T2 (en) | 2016-12-28 |
| JP2011529469A (ja) | 2011-12-08 |
| BRPI0916197A2 (pt) | 2015-11-03 |
| CN102112425A (zh) | 2011-06-29 |
| PL2344435T3 (pl) | 2016-07-29 |
| US20110184169A1 (en) | 2011-07-28 |
| MX2011001004A (es) | 2011-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |