IL205487A - Antibodies familiar with an epitope containing carbohydrates on 43-cd and cea-expressed cancer cells and methods for their use - Google Patents
Antibodies familiar with an epitope containing carbohydrates on 43-cd and cea-expressed cancer cells and methods for their useInfo
- Publication number
- IL205487A IL205487A IL205487A IL20548710A IL205487A IL 205487 A IL205487 A IL 205487A IL 205487 A IL205487 A IL 205487A IL 20548710 A IL20548710 A IL 20548710A IL 205487 A IL205487 A IL 205487A
- Authority
- IL
- Israel
- Prior art keywords
- methods
- same
- cancer cells
- antibodies recognizing
- carbohydrate containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1471607P | 2007-12-18 | 2007-12-18 | |
| PCT/US2008/087515 WO2009079649A1 (en) | 2007-12-18 | 2008-12-18 | Antibodies recognizing a carbohydrate containing epitope on cd-43 and cea expressed on cancer cells and methods using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL205487A0 IL205487A0 (en) | 2010-12-30 |
| IL205487A true IL205487A (en) | 2017-02-28 |
Family
ID=40578003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL205487A IL205487A (en) | 2007-12-18 | 2010-05-02 | Antibodies familiar with an epitope containing carbohydrates on 43-cd and cea-expressed cancer cells and methods for their use |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US7982017B2 (OSRAM) |
| EP (1) | EP2245063B1 (OSRAM) |
| JP (2) | JP5568478B2 (OSRAM) |
| KR (1) | KR101672271B1 (OSRAM) |
| CN (2) | CN101918448A (OSRAM) |
| AU (1) | AU2008338313B2 (OSRAM) |
| BR (1) | BRPI0820452A2 (OSRAM) |
| CA (1) | CA2706502C (OSRAM) |
| DK (1) | DK2245063T3 (OSRAM) |
| ES (1) | ES2550757T3 (OSRAM) |
| HU (1) | HUE026846T2 (OSRAM) |
| IL (1) | IL205487A (OSRAM) |
| NZ (1) | NZ585959A (OSRAM) |
| RU (1) | RU2528738C2 (OSRAM) |
| SG (1) | SG186669A1 (OSRAM) |
| TW (1) | TWI439545B (OSRAM) |
| WO (1) | WO2009079649A1 (OSRAM) |
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| SG172684A1 (en) | 2006-06-07 | 2011-07-28 | Bioalliance Cv | Antibodies recognizing a carbohydrate containing epitope on cd-43 and cea expressed on cancer cells and methods using same |
| EP2769729B1 (en) | 2007-09-04 | 2019-01-09 | Compugen Ltd. | Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics |
| CA2700701C (en) | 2007-09-26 | 2020-12-29 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substitution in cdr |
| CL2008002886A1 (es) | 2007-09-26 | 2009-12-04 | Chugai Pharmaceutical Co Ltd | Region constante de un anticuerpo humano; anticuerpo anti-receptor de interleucina-6 (il-6) y composicion farmaceutica que la comprende. |
| ES2550757T3 (es) | 2007-12-18 | 2015-11-12 | Bioalliance C.V. | Anticuerpos que reconocen un epítopo que contiene carbohidratos en CD43 y ACE expresados en células cancerosas y métodos de uso de los mismos |
| WO2010107110A1 (ja) | 2009-03-19 | 2010-09-23 | 中外製薬株式会社 | 抗体定常領域改変体 |
| EP2826789A1 (en) | 2009-03-19 | 2015-01-21 | Chugai Seiyaku Kabushiki Kaisha | Antibody constant region variant |
| EP2481752B1 (en) * | 2009-09-24 | 2016-11-09 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant regions |
| WO2011108714A1 (ja) | 2010-03-04 | 2011-09-09 | 中外製薬株式会社 | 抗体定常領域改変体 |
| KR101244708B1 (ko) | 2010-10-07 | 2013-03-18 | 기아자동차주식회사 | 측면 조립형 트랜스미션 마운트 |
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| AU2013364065B2 (en) | 2012-12-21 | 2018-10-04 | Altrubio Inc. | Hydrophilic self-immolative linkers and conjugates thereof |
| MX362970B (es) | 2013-03-13 | 2019-02-28 | Medimmune Ltd | Pirrolobenzodiazepinas y conjugados de las mismas. |
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| EP2871190A1 (en) * | 2013-11-11 | 2015-05-13 | ATLAB Pharma | Antibody against GD2-O-acetylated ganglioside with pro-apoptotic activity |
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| MX2018007781A (es) | 2015-12-28 | 2018-09-05 | Chugai Pharmaceutical Co Ltd | Metodo para promover la eficiencia de purificacion del polipeptido que contiene la region de fragmento cristalizable (fc). |
| TWI753875B (zh) | 2016-01-08 | 2022-02-01 | 美商美國全心醫藥生技股份有限公司 | 四價抗psgl-1抗體及其用途 |
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| SG11202010469QA (en) | 2018-05-23 | 2020-11-27 | Adc Therapeutics Sa | Molecular adjuvant |
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| JP7578289B2 (ja) * | 2018-12-21 | 2024-11-06 | マルチチュード インコーポレーテッド | Muc18に特異的な抗体 |
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2008
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- 2008-12-18 TW TW097149465A patent/TWI439545B/zh not_active IP Right Cessation
- 2008-12-18 DK DK08863057.9T patent/DK2245063T3/en active
- 2008-12-18 EP EP08863057.9A patent/EP2245063B1/en not_active Not-in-force
- 2008-12-18 CN CN2008801215817A patent/CN101918448A/zh active Pending
- 2008-12-18 NZ NZ585959A patent/NZ585959A/xx not_active IP Right Cessation
- 2008-12-18 RU RU2010129423/10A patent/RU2528738C2/ru not_active IP Right Cessation
- 2008-12-18 CA CA2706502A patent/CA2706502C/en not_active Expired - Fee Related
- 2008-12-18 CN CN201610109151.XA patent/CN105732813A/zh active Pending
- 2008-12-18 HU HUE08863057A patent/HUE026846T2/en unknown
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| ES2550757T3 (es) | 2015-11-12 |
| EP2245063A1 (en) | 2010-11-03 |
| AU2008338313B2 (en) | 2014-01-16 |
| KR20100097661A (ko) | 2010-09-03 |
| US7982017B2 (en) | 2011-07-19 |
| HK1150167A1 (en) | 2011-11-04 |
| IL205487A0 (en) | 2010-12-30 |
| US8568718B2 (en) | 2013-10-29 |
| DK2245063T3 (en) | 2015-12-07 |
| US9334329B2 (en) | 2016-05-10 |
| JP5568478B2 (ja) | 2014-08-06 |
| RU2528738C2 (ru) | 2014-09-20 |
| CN105732813A (zh) | 2016-07-06 |
| JP2011505875A (ja) | 2011-03-03 |
| RU2010129423A (ru) | 2012-01-27 |
| US20140105899A1 (en) | 2014-04-17 |
| CN101918448A (zh) | 2010-12-15 |
| CA2706502C (en) | 2018-08-07 |
| NZ585959A (en) | 2012-09-28 |
| BRPI0820452A2 (pt) | 2015-06-16 |
| HUE026846T2 (en) | 2016-08-29 |
| WO2009079649A1 (en) | 2009-06-25 |
| US20090191221A1 (en) | 2009-07-30 |
| JP2013247963A (ja) | 2013-12-12 |
| CA2706502A1 (en) | 2009-06-25 |
| SG186669A1 (en) | 2013-01-30 |
| US20110280888A1 (en) | 2011-11-17 |
| KR101672271B1 (ko) | 2016-11-03 |
| TW200938629A (en) | 2009-09-16 |
| EP2245063B1 (en) | 2015-08-26 |
| AU2008338313A1 (en) | 2009-06-25 |
| TWI439545B (zh) | 2014-06-01 |
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