IL186880A0 - Evolved interferon alpha polypeptides - Google Patents

Evolved interferon alpha polypeptides

Info

Publication number
IL186880A0
IL186880A0 IL186880A IL18688007A IL186880A0 IL 186880 A0 IL186880 A0 IL 186880A0 IL 186880 A IL186880 A IL 186880A IL 18688007 A IL18688007 A IL 18688007A IL 186880 A0 IL186880 A0 IL 186880A0
Authority
IL
Israel
Prior art keywords
interferon alpha
alpha polypeptides
evolved interferon
evolved
polypeptides
Prior art date
Application number
IL186880A
Other languages
English (en)
Original Assignee
Maxygen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxygen Inc filed Critical Maxygen Inc
Publication of IL186880A0 publication Critical patent/IL186880A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL186880A 2005-05-18 2007-10-24 Evolved interferon alpha polypeptides IL186880A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68276905P 2005-05-18 2005-05-18
PCT/US2006/019088 WO2007044083A2 (en) 2005-05-18 2006-05-17 Evolved interferon-alpha polypeptides

Publications (1)

Publication Number Publication Date
IL186880A0 true IL186880A0 (en) 2008-02-09

Family

ID=37943260

Family Applications (1)

Application Number Title Priority Date Filing Date
IL186880A IL186880A0 (en) 2005-05-18 2007-10-24 Evolved interferon alpha polypeptides

Country Status (11)

Country Link
US (1) US7619067B2 (enExample)
EP (1) EP1888633A4 (enExample)
JP (1) JP2008545393A (enExample)
KR (1) KR20080019619A (enExample)
CN (1) CN101501068A (enExample)
AU (1) AU2006299901A1 (enExample)
BR (1) BRPI0609809A2 (enExample)
CA (1) CA2607651A1 (enExample)
IL (1) IL186880A0 (enExample)
MX (1) MX2007014524A (enExample)
WO (1) WO2007044083A2 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000040715A2 (en) 1999-01-05 2000-07-13 Trustees Of Boston University Improved nucleic acid cloning
US7435562B2 (en) 2000-07-21 2008-10-14 Modular Genetics, Inc. Modular vector systems
US7485423B2 (en) 2004-11-11 2009-02-03 Modular Genetics, Inc. Ladder assembly and system for generating diversity
US7625555B2 (en) * 2007-06-18 2009-12-01 Novagen Holding Corporation Recombinant human interferon-like proteins
KR101502645B1 (ko) * 2007-09-04 2015-03-13 바이오스티드 진 익스프레션 테크. 컴파니 리미티드 폴리에틸렌 글리콜에 의해 변형된 인터페론 알파 2ｂ, 이의 제조 방법 및 용도
AT506535B1 (de) * 2008-02-22 2010-04-15 Affiris Forschungs & Entwicklungs Gmbh Vaccine enthaltend alpha-synuclein-mimotope auf basis von peptiden
CN102057054B (zh) 2008-04-11 2015-06-10 梅里麦克制药股份有限公司 人血清白蛋白接头以及其结合物
BRPI0910686A2 (pt) 2008-04-21 2015-09-29 Tissue Regeneration Therapeutics Inc células perivasculares do cordão umbilical humano geneticamente modificadas para a profilaxia contra agentes biológicos e químicos ou para o tratamento dos mesmos.
BRPI1012951A2 (pt) 2009-06-09 2016-07-26 Defyrus Inc "administração de interferon para profilaxia ou tratamento de infecção por patôgeno"
CN101921330B (zh) * 2010-06-02 2013-07-17 北京三元基因工程有限公司 重组人干扰素α1b突变体及其制备方法
LT2822575T (lt) 2012-03-03 2020-06-25 Immungene, Inc. Sukonstruotos antikūno-mutantinio interferono sulietos molekulės
HUE065662T2 (hu) * 2015-09-15 2024-06-28 Ilc Therapeutics Ltd Készítmények és eljárások betegségek kezelésére
CN108733975B (zh) * 2018-03-29 2021-09-07 深圳裕策生物科技有限公司 基于二代测序的肿瘤克隆变异检测方法、装置和存储介质
CN111499718B (zh) * 2019-01-30 2022-06-14 复旦大学 人α干扰素受体结合相关位点突变体及其用途
CN114891088B (zh) * 2019-06-13 2023-07-25 江苏科技大学 鸭α干扰素及其突变体、制备方法和应用
AU2021238925A1 (en) * 2020-03-16 2022-10-27 ILC Therapeutics Limited Hybrid interferons for treating viral infections
EP3901168A1 (en) * 2020-04-21 2021-10-27 Universität Duisburg-Essen Interferon alpha 2 variants and uses thereof

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610830B1 (en) * 1980-07-01 2003-08-26 Hoffman-La Roche Inc. Microbial production of mature human leukocyte interferons
ES506955A0 (es) 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
US4414150A (en) * 1980-11-10 1983-11-08 Genentech, Inc. Hybrid human leukocyte interferons
EP0098876A1 (en) 1982-01-19 1984-01-25 Cetus Corporation Multiclass hybrid interferons
US6936694B1 (en) * 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US4885166A (en) 1985-06-11 1989-12-05 Ciba-Geigy Corporation Hybrid interferons
ATE174798T1 (de) 1990-10-17 1999-01-15 Amgen Inc Die herstellung von zusammensetzungen zur behandlung von krankheiten der zellproliferation
US5372808A (en) 1990-10-17 1994-12-13 Amgen Inc. Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
US5595732A (en) * 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) * 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
US5780021A (en) * 1993-03-05 1998-07-14 Georgetown University Method for treating type 1 diabetes using α-interferon and/or β-i
US5574138A (en) * 1993-03-08 1996-11-12 Immunex Corporation Epithelium-derived T-cell factor
US6335160B1 (en) * 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
PT741577E (pt) 1994-03-07 2003-03-31 Imperial College Utilizacao do subtipo de interferao alfa 8 na preparacao de medicamentos para tratar infeccoes virais do figado
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
TW517067B (en) * 1996-05-31 2003-01-11 Hoffmann La Roche Interferon conjugates
IL133974A0 (en) 1997-07-14 2001-04-30 Bolder Biotechnology Inc Derivatives of growth hormone and related proteins
NZ513077A (en) 1999-01-14 2004-03-26 Bolder Biotechnology Inc Methods for making proteins containing free cysteine residues
AU3725600A (en) 1999-03-02 2000-09-21 Maxygen, Inc. Surrogate orphan ligands for orphan receptors
DE60035871T2 (de) 1999-05-19 2008-06-05 Merck Patent Gmbh Expression und export von interferon-alpha proteinen als fc fusionsproteine
US20040002474A1 (en) * 1999-10-07 2004-01-01 Maxygen Inc. IFN-alpha homologues
WO2001025438A2 (en) * 1999-10-07 2001-04-12 Maxygen, Inc. Ifn-alpha homologues
JP4873818B2 (ja) 2000-05-16 2012-02-08 ボルダー バイオテクノロジー， インコーポレイテッド 遊離システイン残基を含有するタンパク質をリフォールディングする方法
WO2002044197A2 (en) 2000-12-01 2002-06-06 Fish Eleanor N Cytokine receptor binding peptides
KR100459105B1 (ko) 2001-02-15 2004-12-03 선바이오(주) 변형된 인터페론-알파 2ａ 및 2ｂ, 그리고 이들과 ＰＥＧ유도체와의 배합체
CA2503594C (en) * 2002-11-15 2011-05-10 Doris Brugger Positional isomers of peg ifn alpha 2a
NZ540043A (en) * 2002-11-18 2007-11-30 Maxygen Inc Isolated or recombinant Interferon-alpha polypeptides and conjugates
US7318918B2 (en) 2004-05-19 2008-01-15 Maxygen, Inc. Interferon-alpha polypeptides and conjugates

Also Published As

Publication number Publication date
CN101501068A (zh) 2009-08-05
WO2007044083A2 (en) 2007-04-19
WO2007044083A3 (en) 2009-04-16
US20080226597A1 (en) 2008-09-18
EP1888633A2 (en) 2008-02-20
US7619067B2 (en) 2009-11-17
BRPI0609809A2 (pt) 2011-10-11
CA2607651A1 (en) 2007-04-19
MX2007014524A (es) 2008-02-07
AU2006299901A1 (en) 2007-04-19
JP2008545393A (ja) 2008-12-18
KR20080019619A (ko) 2008-03-04
EP1888633A4 (en) 2010-01-27

Similar Documents

Publication Publication Date Title
IL186880A0 (en) Evolved interferon alpha polypeptides
IL184428A0 (en) Peptides with neuropeptide-2-receptor
GB0524788D0 (en) Polypeptides
ZA200700895B (en) Polypeptide
GB0508863D0 (en) Peptide
GB0621513D0 (en) Novel polypeptides and uses thereof
EP1868636A4 (en) USE OF RECOMBINANT SUPERCOMPOSE INTERFERONS
GB0505975D0 (en) Novel use of peptide
ZA200610812B (en) Keratin-binding polypeptides
GB0423974D0 (en) Proteins
AP2008004512A0 (en) Bacteriocion inducer peptides
GB0505949D0 (en) Polypeptides
GB0526019D0 (en) Peptides
IL170762A0 (en) Improved alumina-based ceramic objects
GB0415196D0 (en) Polypeptide
GB0516527D0 (en) Peptides
GB0402904D0 (en) Polypeptide
GB0516571D0 (en) Novel polypeptides and uses thereof
GB2401581B (en) Ceramic labelling
GB0504769D0 (en) Polypeptides
GB0423002D0 (en) Proteins
GB0511861D0 (en) Proteins
GB0400606D0 (en) Polypeptide
GB0400605D0 (en) Polypeptide
GB0522113D0 (en) vWFA-domain containing proteins