IL178847A - Human cell culture comprising pdx1 expressing positive foregut endoderm multipotent cells - Google Patents

Human cell culture comprising pdx1 expressing positive foregut endoderm multipotent cells

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Publication number
IL178847A
IL178847A IL178847A IL17884706A IL178847A IL 178847 A IL178847 A IL 178847A IL 178847 A IL178847 A IL 178847A IL 17884706 A IL17884706 A IL 17884706A IL 178847 A IL178847 A IL 178847A
Authority
IL
Israel
Prior art keywords
cells
pdxl
cell
expression
endoderm
Prior art date
Application number
IL178847A
Other languages
English (en)
Other versions
IL178847A0 (en
Original Assignee
Viacyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/021,618 external-priority patent/US7510876B2/en
Application filed by Viacyte Inc filed Critical Viacyte Inc
Publication of IL178847A0 publication Critical patent/IL178847A0/en
Publication of IL178847A publication Critical patent/IL178847A/en

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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
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    • C12N5/0676Pancreatic cells
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
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    • C12N5/0679Cells of the gastro-intestinal tract
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/385Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/02Coculture with; Conditioned medium produced by embryonic cells
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    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
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    • C12N2503/00Use of cells in diagnostics
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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    • C12N2510/00Genetically modified cells

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  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL178847A 2004-04-27 2006-10-24 Human cell culture comprising pdx1 expressing positive foregut endoderm multipotent cells IL178847A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56629304P 2004-04-27 2004-04-27
US58656604P 2004-07-09 2004-07-09
US58794204P 2004-07-14 2004-07-14
US11/021,618 US7510876B2 (en) 2003-12-23 2004-12-23 Definitive endoderm
PCT/US2005/014239 WO2005116073A2 (en) 2004-04-27 2005-04-26 Pdx1 expressing endoderm

Publications (2)

Publication Number Publication Date
IL178847A0 IL178847A0 (en) 2007-03-08
IL178847A true IL178847A (en) 2012-01-31

Family

ID=45319532

Family Applications (1)

Application Number Title Priority Date Filing Date
IL178847A IL178847A (en) 2004-04-27 2006-10-24 Human cell culture comprising pdx1 expressing positive foregut endoderm multipotent cells

Country Status (14)

Country Link
EP (1) EP1740612B1 (enExample)
JP (6) JP4926946B2 (enExample)
KR (2) KR101278421B1 (enExample)
CN (1) CN103103158B (enExample)
AU (1) AU2005247869B2 (enExample)
CA (1) CA2564114C (enExample)
DK (2) DK2377922T3 (enExample)
EA (1) EA011953B1 (enExample)
ES (2) ES2801001T3 (enExample)
IL (1) IL178847A (enExample)
MX (1) MXPA06012445A (enExample)
NZ (1) NZ550605A (enExample)
SG (1) SG152273A1 (enExample)
WO (1) WO2005116073A2 (enExample)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
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US7985585B2 (en) 2004-07-09 2011-07-26 Viacyte, Inc. Preprimitive streak and mesendoderm cells
US20050266554A1 (en) 2004-04-27 2005-12-01 D Amour Kevin A PDX1 expressing endoderm
US8647873B2 (en) 2004-04-27 2014-02-11 Viacyte, Inc. PDX1 expressing endoderm
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EP1786896B1 (en) * 2004-07-09 2018-01-10 Viacyte, Inc. Methods for identifying factors for differentiating definitive endoderm
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